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| NCT ID | NCT04494425 |
| Title | Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer (DB-06) |
| Acronym | DB-06 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | Scottsdale | Arizona | 85259 | United States | Details | |
| Research Site | Springdale | Arkansas | 72762 | United States | Details | |
| Research Site | Duarte | California | 91010 | United States | Details | |
| Research Site | Los Angeles | California | 90017 | United States | Details | |
| Research Site | Aurora | Colorado | 80045 | United States | Details | |
| Research Site | Lakewood | Colorado | 80228 | United States | Details | |
| Research Site | Washington | District of Columbia | 20016 | United States | Details | |
| Research Site | Jacksonville | Florida | 32224 | United States | Details | |
| Research Site | Kansas City | Kansas | 66160 | United States | Details | |
| Research Site | Louisville | Kentucky | 40202 | United States | Details | |
| Research Site | Bethesda | Maryland | 20817 | United States | Details | |
| Research Site | Boston | Massachusetts | 02114 | United States | Details | |
| Research Site | Detroit | Michigan | 48202 | United States | Details | |
| Research Site | Rochester | Minnesota | 55905 | United States | Details | |
| Research Site | Saint Louis | Missouri | 63110 | United States | Details | |
| Research Site | Summit | New Jersey | 07901 | United States | Details | |
| Research Site | Westbury | New York | 11590 | United States | Details | |
| Research Site | Columbus | Ohio | 43210 | United States | Details | |
| Research Site | Pittsburgh | Pennsylvania | 15212 | United States | Details | |
| Research Site | Nashville | Tennessee | 37232 | United States | Details | |
| Research Site | Austin | Texas | 78731 | United States | Details | |
| Research Site | Dallas | Texas | 75246 | United States | Details | |
| Research Site | Houston | Texas | 77030 | United States | Details | |
| Research Site | Houston | Texas | 77090 | United States | Details | |
| Research Site | Norfolk | Virginia | 23502 | United States | Details | |
| Research Site | Seattle | Washington | 98104 | United States | Details | |
| Research Site | Madison | Wisconsin | 53792-5666 | United States | Details | |
| Research Site | Buenos Aires | C1125ABD | Argentina | Details | ||
| Research Site | Caba | 1414 | Argentina | Details | ||
| Research Site | Caba | C1012AAR | Argentina | Details | ||
| Research Site | Caba | C1019ABS | Argentina | Details | ||
| Research Site | Ciudad de Buenos Aires | 1280 | Argentina | Details | ||
| Research Site | Cordoba | 5000 | Argentina | Details | ||
| Research Site | La Plata | 1900 | Argentina | Details | ||
| Research Site | Mar del Plata | 7600 | Argentina | Details | ||
| Research Site | Rosario | S2000DEJ | Argentina | Details | ||
| Research Site | Rosario | S2002KDS | Argentina | Details | ||
| Research Site | Adelaide | 5000 | Australia | Details | ||
| Research Site | Birtinya | 4575 | Australia | Details | ||
| Research Site | Darlinghurst | 2010 | Australia | Details | ||
| Research Site | Murdoch | 6150 | Australia | Details | ||
| Research Site | South Brisbane | 4101 | Australia | Details | ||
| Research Site | St Leonards | 2065 | Australia | Details | ||
| Research Site | Waratah | 2298 | Australia | Details | ||
| Research Site | Graz | 8036 | Austria | Details | ||
| Research Site | Innsbruck | 6020 | Austria | Details | ||
| Research Site | Anderlecht | 1070 | Belgium | Details | ||
| Research Site | Bruxelles | 1200 | Belgium | Details | ||
| Research Site | Charleroi | 6000 | Belgium | Details | ||
| Research Site | Edegem | 2650 | Belgium | Details | ||
| Research Site | Gent | 9000 | Belgium | Details | ||
| Research Site | Leuven | 3000 | Belgium | Details | ||
| Research Site | Liège | 4000 | Belgium | Details | ||
| Research Site | Namur | 5000 | Belgium | Details | ||
| Research Site | Roeselare | 8800 | Belgium | Details | ||
| Research Site | Sint-Niklaas | 9100 | Belgium | Details | ||
| Research Site | Barretos | 14784-400 | Brazil | Details | ||
| Research Site | Belo Horizonte | 30110-022 | Brazil | Details | ||
| Research Site | Natal | 59075-740 | Brazil | Details | ||
| Research Site | Porto Alegre | 90610-000 | Brazil | Details | ||
| Research Site | Porto Alegre | 91350-200 | Brazil | Details | ||
| Research Site | Rio de Janeiro | 20560-120 | Brazil | Details | ||
| Research Site | Sao Paulo | 1323001 | Brazil | Details | ||
| Research Site | Sorocaba | 18030-510 | Brazil | Details | ||
| Research Site | São Paulo | 04038-034 | Brazil | Details | ||
| Research Site | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Research Site | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Research Site | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Research Site | Toronto | CA | M5G 2M9 | Canada | Details | |
| Research Site | London | Ontario | N6A 5W9 | Canada | Details | |
| Research Site | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Research Site | Toronto | Ontario | M5G 1X5 | Canada | Details | |
| Research Site | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Research Site | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Research Site | Sherbrooke | Quebec | J1H 5N4 | Canada | Details | |
| Research Site | Baoding | 071000 | China | Details | ||
| Research Site | Beijing | 100006 | China | Details | ||
| Research Site | Beijing | 100044 | China | Details | ||
| Research Site | Changchun | 130021 | China | Details | ||
| Research Site | Changsha | 410008 | China | Details | ||
| Research Site | Changsha | 410013 | China | Details | ||
| Research Site | Dalian | 116001 | China | Details | ||
| Research Site | Foshan | 528000 | China | Details | ||
| Research Site | Fuzhou | 350011 | China | Details | ||
| Research Site | Guangzhou | 510060 | China | Details | ||
| Research Site | Guangzhou | 510080 | China | Details | ||
| Research Site | Guangzhou | 510120 | China | Details | ||
| Research Site | Hangzhou | 310003 | China | Details | ||
| Research Site | Hangzhou | 310020 | China | Details | ||
| Research Site | Hangzhou | 310022 | China | Details | ||
| Research Site | Harbin | 150001 | China | Details | ||
| Research Site | Hefei | 230001 | China | Details | ||
| Research Site | Jinan | 250001 | China | Details | ||
| Research Site | Linyi | 276000 | China | Details | ||
| Research Site | Nanchang | 330006 | China | Details | ||
| Research Site | Nanchang | 330009 | China | Details | ||
| Research Site | Nanjing | 210009 | China | Details | ||
| Research Site | Nanjing | 210029 | China | Details | ||
| Research Site | Nanning | 530021 | China | Details | ||
| Research Site | Shanghai | 200032 | China | Details | ||
| Research Site | Shenyang | China | Details | |||
| Research Site | Tianjin | 300060 | China | Details | ||
| Research Site | Urumqi | 830000 | China | Details | ||
| Research Site | Wuhan | 430079 | China | Details | ||
| Research Site | Xi'an | 710004 | China | Details | ||
| Research Site | Xi'an | 710061 | China | Details | ||
| Research Site | Zhengzhou | 450008 | China | Details | ||
| Research Site | Aalborg | 9000 | Denmark | Details | ||
| Research Site | Copenhagen Ø | 2100 | Denmark | Details | ||
| Research Site | Odense C | 5000 | Denmark | Details | ||
| Research Site | Vejle | 7100 | Denmark | Details | ||
| Research Site | Avignon Cedex 09 | 84918 | France | Details | ||
| Research Site | Besançon | 25000 | France | Details | ||
| Research Site | Bordeaux | 33000 | France | Details | ||
| Research Site | Brest | 29609 | France | Details | ||
| Research Site | Caen Cedex 05 | 14076 | France | Details | ||
| Research Site | Dijon | 21079 | France | Details | ||
| Research Site | Le Mans | 72000 | France | Details | ||
| Research Site | Marseille | 13273 | France | Details | ||
| Research Site | Montpellier | 34298 | France | Details | ||
| Research Site | Nice | 06100 | France | Details | ||
| Research Site | Paris | 75005 | France | Details | ||
| Research Site | Pierre Benite | 69495 | France | Details | ||
| Research Site | Plerin SUR MER | 22190 | France | Details | ||
| Research Site | Rennes | 35000 | France | Details | ||
| Research Site | Saint Herblain Cedex | 44805 | France | Details | ||
| Research Site | Saint-cloud | 92210 | France | Details | ||
| Research Site | Tours | 37000 | France | Details | ||
| Research Site | Villejuif Cedex | 94805 | France | Details | ||
| Research Site | Berlin | 10117 | Germany | Details | ||
| Research Site | Dresden | 01307 | Germany | Details | ||
| Research Site | Freiburg | 79110 | Germany | Details | ||
| Research Site | Hannover | 30625 | Germany | Details | ||
| Research Site | München | 80337 | Germany | Details | ||
| Research Site | München | 81675 | Germany | Details | ||
| Research Site | Münster | 48149 | Germany | Details | ||
| Research Site | Velbert | 42551 | Germany | Details | ||
| Research Site | Budapest | 1062 | Hungary | Details | ||
| Research Site | Budapest | 1122 | Hungary | Details | ||
| Research Site | Budapest | 1145 | Hungary | Details | ||
| Research Site | Győr | 9024 | Hungary | Details | ||
| Research Site | Kecskemét | 6000 | Hungary | Details | ||
| Research Site | Nyíregyháza | 4400 | Hungary | Details | ||
| Research Site | Szolnok | 5000 | Hungary | Details | ||
| Research Site | Tatabánya | 2800 | Hungary | Details | ||
| Research Site | Bengaluru | 560099 | India | Details | ||
| Research Site | Calicut | 673601 | India | Details | ||
| Research Site | Kolkata | 700160 | India | Details | ||
| Research Site | Marg Jaipur | 302004 | India | Details | ||
| Research Site | New Delhi | 110 085 | India | Details | ||
| Research Site | New Delhi | 110005 | India | Details | ||
| Research Site | New Delhi | 110017 | India | Details | ||
| Research Site | New Delhi | 110075 | India | Details | ||
| Research Site | Surat | 395002 | India | Details | ||
| Research Site | Thiruvananthapuram | 695011 | India | Details | ||
| Research Site | Haifa | 3109601 | Israel | Details | ||
| Research Site | Jerusalem | 9103102 | Israel | Details | ||
| Research Site | Jerusalem | 91120 | Israel | Details | ||
| Research Site | Kfar-Saba | 44281 | Israel | Details | ||
| Research Site | Petah Tikva | 49100 | Israel | Details | ||
| Research Site | Ramat Gan | 52621 | Israel | Details | ||
| Research Site | Tel-Aviv | 64239 | Israel | Details | ||
| Research Site | Aviano | 33081 | Italy | Details | ||
| Research Site | Bergamo | 24127 | Italy | Details | ||
| Research Site | Candiolo | 10060 | Italy | Details | ||
| Research Site | Cona | 44124 | Italy | Details | ||
| Research Site | Genova | 16132 | Italy | Details | ||
| Research Site | Livorno | 57124 | Italy | Details | ||
| Research Site | Messina | 98158 | Italy | Details | ||
| Research Site | Milano | 20132 | Italy | Details | ||
| Research Site | Milan | 20141 | Italy | Details | ||
| Research Site | Napoli | 80131 | Italy | Details | ||
| Research Site | Padova | 35128 | Italy | Details | ||
| Research Site | Parma | Italy | Details | |||
| Research Site | Prato | 59100 | Italy | Details | ||
| Research Site | Tricase, Lecce | 73039 | Italy | Details | ||
| Research Site | Udine | 33100 | Italy | Details | ||
| Research Site | Akashi-shi | 673-8558 | Japan | Details | ||
| Research Site | Bunkyo-ku | 113-8431 | Japan | Details | ||
| Research Site | Chiba-shi | 260-8717 | Japan | Details | ||
| Research Site | Chuo-ku | 104-0045 | Japan | Details | ||
| Research Site | Fukuoka-shi | 811-1395 | Japan | Details | ||
| Research Site | Gifu-shi | 501-1194 | Japan | Details | ||
| Research Site | Hidaka-shi | 350-1298 | Japan | Details | ||
| Research Site | Hiroshima-shi | 730-8518 | Japan | Details | ||
| Research Site | Isehara | 259-1193 | Japan | Details | ||
| Research Site | Kagoshima-shi | 892-0833 | Japan | Details | ||
| Research Site | Kashiwa | 277-8577 | Japan | Details | ||
| Research Site | Kawasaki-shi | 216-8511 | Japan | Details | ||
| Research Site | Kitaadachi-gun | 362-0806 | Japan | Details | ||
| Research Site | Koto-ku | 135-8550 | Japan | Details | ||
| Research Site | Matsuyama-shi | 791-0280 | Japan | Details | ||
| Research Site | Nagoya | 460-0001 | Japan | Details | ||
| Research Site | Naha-shi | 901-0154 | Japan | Details | ||
| Research Site | Niigata-shi | 951-8566 | Japan | Details | ||
| Research Site | Nishinomiya-shi | 663-8501 | Japan | Details | ||
| Research Site | Okayama-shi | 700-8558 | Japan | Details | ||
| Research Site | Osaka-shi | 541-8567 | Japan | Details | ||
| Research Site | Osakasayama-shi | 589-8511 | Japan | Details | ||
| Research Site | Sagamihara-shi | 252-0375 | Japan | Details | ||
| Research Site | Sapporo-shi | 060-8648 | Japan | Details | ||
| Research Site | Shinagawa-ku | 142-8666 | Japan | Details | ||
| Research Site | Shinjuku-ku | 160-0023 | Japan | Details | ||
| Research Site | Shizuoka | 420-8527 | Japan | Details | ||
| Research Site | Tsu-shi | 514-8507 | Japan | Details | ||
| Research Site | Yokohama-shi | 241-8515 | Japan | Details | ||
| Research Site | Daegu | 41404 | Korea, Republic of | Details | ||
| Research Site | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Research Site | Incheon | 22332 | Korea, Republic of | Details | ||
| Research Site | Seongnam-si | 13620 | Korea, Republic of | Details | ||
| Research Site | Seoul | 02841 | Korea, Republic of | Details | ||
| Research Site | Seoul | 03080 | Korea, Republic of | Details | ||
| Research Site | Seoul | 03722 | Korea, Republic of | Details | ||
| Research Site | Seoul | 05505 | Korea, Republic of | Details | ||
| Research Site | Seoul | 06351 | Korea, Republic of | Details | ||
| Research Site | Alc. Cuauhtémoc | 06700 | Mexico | Details | ||
| Research Site | Guadalajara Jalisco | 44280 | Mexico | Details | ||
| Research Site | Guadalajra | 44260 | Mexico | Details | ||
| Research Site | Mexico City | '14080 | Mexico | Details | ||
| Research Site | Mexico City | 0 3100 | Mexico | Details | ||
| Research Site | Mexico, D.F. | 6760 | Mexico | Details | ||
| Research Site | Monterrey | 64460 | Mexico | Details | ||
| Research Site | México | 04700 | Mexico | Details | ||
| Research Site | Nuevo Leon | 66278 | Mexico | Details | ||
| Research Site | Amsterdam | 1066 CX | Netherlands | Details | ||
| Research Site | Breda | 4818 CK | Netherlands | Details | ||
| Research Site | Hengelo | 7555 DL | Netherlands | Details | ||
| Research Site | Leeuwarden | 8934 AD | Netherlands | Details | ||
| Research Site | Rotterdam | 3015 GD | Netherlands | Details | ||
| Research Site | Sittard-Geleen | 6162 BG | Netherlands | Details | ||
| Research Site | Bydgoszcz | 85-796 | Poland | Details | ||
| Research Site | Koszalin | 75-581 | Poland | Details | ||
| Research Site | Kraków | 31-501 | Poland | Details | ||
| Research Site | Rzeszów | 35-021 | Poland | Details | ||
| Research Site | Warszawa | 02-781 | Poland | Details | ||
| Research Site | Wroclaw | 53-413 | Poland | Details | ||
| Research Site | Łódź | 90-302 | Poland | Details | ||
| Research Site | Lisboa | 1500-650 | Portugal | Details | ||
| Research Site | Lisboa | 1649-035 | Portugal | Details | ||
| Research Site | Lisboa | 1998-018 | Portugal | Details | ||
| Research Site | Krasnodar | 350040 | Russian Federation | Details | ||
| Research Site | Moscow | 111123 | Russian Federation | Details | ||
| Research Site | Moscow | 115478 | Russian Federation | Details | ||
| Research Site | Moscow | 117997 | Russian Federation | Details | ||
| Research Site | Moscow | 121205 | Russian Federation | Details | ||
| Research Site | Saint Petersburg | 195271 | Russian Federation | Details | ||
| Research Site | Saint Petersburg | 197758 | Russian Federation | Details | ||
| Research Site | Saint-Petersburg | 190103 | Russian Federation | Details | ||
| Research Site | Sankt-Peterburg | 197758 | Russian Federation | Details | ||
| Research Site | Yaroslavl | 150054 | Russian Federation | Details | ||
| Research Site | Ar Riyāḑ | 11426 | Saudi Arabia | Details | ||
| Research Site | Dammam | 31444 | Saudi Arabia | Details | ||
| Research Site | Jeddah | 21423 | Saudi Arabia | Details | ||
| Research Site | Jeddah | 23214 | Saudi Arabia | Details | ||
| Research Site | Riyadh | 11525 | Saudi Arabia | Details | ||
| Research Site | Riyadh | 12713 | Saudi Arabia | Details | ||
| Research Site | Bukit Merah | 169610 | Singapore | Details | ||
| Research Site | Singapore | 119074 | Singapore | Details | ||
| Research Site | Singapore | 258499 | Singapore | Details | ||
| Research Site | Singapore | 308433 | Singapore | Details | ||
| Research Site | Singapore | 329563 | Singapore | Details | ||
| Research Site | Barcelona | 08035 | Spain | Details | ||
| Research Site | Barcelona | 08036 | Spain | Details | ||
| Research Site | Barcelona | 08907 | Spain | Details | ||
| Research Site | Cordoba | 14004 | Spain | Details | ||
| Research Site | El Palmar | 30120 | Spain | Details | ||
| Research Site | La Coruña | 15006 | Spain | Details | ||
| Research Site | Madrid | 28005 | Spain | Details | ||
| Research Site | Madrid | 28007 | Spain | Details | ||
| Research Site | Madrid | 28046 | Spain | Details | ||
| Research Site | San Sebastián | 20014 | Spain | Details | ||
| Research Site | Sevilla | 41013 | Spain | Details | ||
| Research Site | Valencia | 46026 | Spain | Details | ||
| Research Site | Göteborg | 413 45 | Sweden | Details | ||
| Research Site | Stockholm | 118 83 | Sweden | Details | ||
| Research Site | Uppsala | 751 85 | Sweden | Details | ||
| Research Site | Växjö | 35185 | Sweden | Details | ||
| Research Site | Örebro | 701 85 | Sweden | Details | ||
| Research Site | Taichung | 40447 | Taiwan | Details | ||
| Research Site | Tainan | 70403 | Taiwan | Details | ||
| Research Site | Tainan | 710 | Taiwan | Details | ||
| Research Site | Taipei | 10048 | Taiwan | Details | ||
| Research Site | Taipei | 10449 | Taiwan | Details | ||
| Research Site | Taipei | 11217 | Taiwan | Details | ||
| Research Site | Taipei | 235 | Taiwan | Details | ||
| Research Site | Tao-Yuan | 333 | Taiwan | Details | ||
| Research Site | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Research Site | Cardiff | CF14 2TL | United Kingdom | Details | ||
| Research Site | Edinburgh | EH4 2XR | United Kingdom | Details | ||
| Research Site | Guildford | United Kingdom | Details | |||
| Research Site | Leeds | LS9 7TF | United Kingdom | Details | ||
| Research Site | London | SE1 9RT | United Kingdom | Details | ||
| Research Site | Manchester | M20 4BX | United Kingdom | Details | ||
| Research Site | Northwood | HA6 2RN | United Kingdom | Details |