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| NCT ID | NCT04538664 |
| Title | A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions (PAPILLON) |
| Acronym | PAPILLON |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Janssen Research & Development, LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope | Duarte | California | 91010 | United States | Details | |
| University of California Irvine | Orange | California | 92868 | United States | Details | |
| UCLA | Santa Monica | California | 90404 | United States | Details | |
| Georgetown University Hospital | Washington | District of Columbia | 20007 | United States | Details | |
| H. Lee Moffitt Cancer & Research Institute | Tampa | Florida | 33612 | United States | Details | |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | United States | Details | |
| Henry Ford Hospital | Detroit | Michigan | 48202 | United States | Details | |
| Washington University Medical Center | Saint Louis | Missouri | 63110 | United States | Details | |
| Regional Cancer Care Associates LLC | East Brunswick | New Jersey | 08816 | United States | Details | |
| Langone Health at NYC University, NYU School of Medicine | New York | New York | 10016 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| Providence Portland Medical Center | Portland | Oregon | 97213 | United States | Details | |
| Sanford Health | Sioux Falls | South Dakota | 57104 | United States | Details | |
| Texas Oncology Pa | Tyler | Texas | 75702 | United States | Details | |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | United States | Details | |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | United States | Details | |
| Blue Ridge Cancer Care | Salem | Virginia | 24153 | United States | Details | |
| Chris O'Brien Lifehouse | Camperdown | 2050 | Australia | Details | ||
| St George Hospital | Kogarah | 2217 | Australia | Details | ||
| Cabrini Medical Centre | Malvern | 3144 | Australia | Details | ||
| Sir Charles Gairdner Hospital | Nedlands | 6009 | Australia | Details | ||
| UZ Leuven | Leuven | 3000 | Belgium | Details | ||
| Algemeen Ziekenhuis Delta | Roeselare | 8800 | Belgium | Details | ||
| CHU UCL Namur - Site Godinne | Yvoir | 5530 | Belgium | Details | ||
| Fundacao Pio XII | Barretos | 14784-400 | Brazil | Details | ||
| Cetus Oncologia | Belo Horizonte | 30110-017 | Brazil | Details | ||
| Ynova Pesquisa Clinica | Florianopolis | 88020-210 | Brazil | Details | ||
| Oncosite - Centro de Pesquisa Clínica em Oncologia Ltda | Ijui | 98700-000 | Brazil | Details | ||
| Liga Norte Riograndense Contra O Cancer | Natal | 59062 000 | Brazil | Details | ||
| UPCO Unidade de Pesquisa Clinica em Oncologia | Pelotas | 96020 080 | Brazil | Details | ||
| Irmandade Santa Casa de Misericordia de Porto Alegre | Porto Alegre | 90020-090 | Brazil | Details | ||
| Uniao Brasileira de Educaçao e Assistencia-Hospital Sao Lucas da PUCRS | Porto Alegre | 90610-000 | Brazil | Details | ||
| Ministerio da Saude - Instituto Nacional do Cancer | Rio De Janeiro | 20231-050 | Brazil | Details | ||
| Oncoclinicas Rio de Janeiro S A | Rio de Janeiro | 22 250 905 | Brazil | Details | ||
| Instituto D Or de Pesquisa e Ensino (IDOR) | Rio de Janeiro | 22281-100 | Brazil | Details | ||
| Fundacao Faculdade de Medicina - Instituto do Cancer do Estado de Sao Paulo | Sao Paulo | 01246-000 | Brazil | Details | ||
| Fundacao Antonio Prudente A C Camargo Cancer Center | Sao Paulo | 01509 900 | Brazil | Details | ||
| Núcleo de Pesquisa São Camilo | Sao Paulo | 04014-002 | Brazil | Details | ||
| IOS - Instituto de Oncologia de Sorocaba Dr. Gilson Delgado | Sorocaba | 18030-075 | Brazil | Details | ||
| Hospital Evangélico de Cachoeiro de Itapemirim | Vitoria | 29308-014 | Brazil | Details | ||
| The Ottawa Hospital Cancer Centre | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Health Sciences Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| McGill University Health Centre | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| Chinese PLA General Hospital | Beijing | 100853 | China | Details | ||
| Beijing Chest hospital, Capital medical university | Beijing | 101199 | China | Details | ||
| Peking University International Hospital | Beijing | 102206 | China | Details | ||
| Jilin cancer hospital | Changchun | 130000 | China | Details | ||
| Hunan Cancer hospital | Changsha | 410013 | China | Details | ||
| The First People's Hospital Of Changzhou | Changzhou | 213003 | China | Details | ||
| West China Hospital Sichuan University | Chengdu | 610041 | China | Details | ||
| Chongqing University Cancer Hospital | Chongqing | 400030 | China | Details | ||
| Fujian Medical University Union Hospital | Fuzhou | 350001 | China | Details | ||
| The First Affiliated Hospital, Sun Yat-sen University | Guang Zhou | 510080 | China | Details | ||
| Zhejiang Cancer Hospital | Hang Zhou | 310022 | China | Details | ||
| The First Affiliated Hospital Zhejiang University College of Medicine | Hangzhou | 310003 | China | Details | ||
| The Second Affiliated Hospital of Zhejiang University College of Medicine | Hangzhou | 310009 | China | Details | ||
| Sir Run Run Shaw Hospital, Zhejiang University School of Medicine | Hangzhou | 310016 | China | Details | ||
| Harbin medical university cancer hospital | Harbin | 150000 | China | Details | ||
| Taizhou Hospital of Zhejiang Province | Linhai | 317000 | China | Details | ||
| Nanjing Drum Tower Hospital | Nanjing | 210031 | China | Details | ||
| Shanghai Chest Hospital | Shanghai | 200030 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai | 200032 | China | Details | ||
| Shanghai East Hospital | Shanghai | 200123 | China | Details | ||
| Shanghai Pulmonary Hospital | Shanghai | 200433 | China | Details | ||
| Shengjing Hospital of China Medical University | Shenyang | 110004 | China | Details | ||
| Cancer hospital Chinese Academy of Medical Sciences, Shenzhen Center | Shenzhen | 518116 | China | Details | ||
| Tianjin Medical University General Hospital | Tianjin | 300052 | China | Details | ||
| Weifang People's Hospital | Weifang | 261000 | China | Details | ||
| TongJi Hospital of TongJi Medical College of Huazhong University of Science & Technology | Wuhan | 430030 | China | Details | ||
| Hospital of Jiangnan University | Wuxi | 214122 | China | Details | ||
| The First Affiliated Hospital of Xian Jiaotong University | XI An | 710061 | China | Details | ||
| Yantai Yuhuangding Hospital | Yantai | 264000 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| Institut Bergonié | Bordeaux | 33000 | France | Details | ||
| Hospices Civils de Lyon HCL | Bron | 69500 | France | Details | ||
| Centre Georges François Leclerc | Dijon | 21000 | France | Details | ||
| Centre Hospitalier Le Mans | le mans Cedex 9 | 72037 | France | Details | ||
| CHR Hôpital Calmette | Lille CEDEX | 59037 | France | Details | ||
| CHU Nantes - Hopital Nord Laënnec | NANTES cedex 1 | 44093 | France | Details | ||
| Institut Curie | Paris | 75005 | France | Details | ||
| CHU Bordeaux | Pessac | 33604 | France | Details | ||
| HIA Begin | Saint Mande | 94163 | France | Details | ||
| Zentralklinik Bad Berka GmbH | Bad Berka | 99437 | Germany | Details | ||
| Evangelische Lungenklinik Berlin | Berlin | 13125 | Germany | Details | ||
| Asklepios Klinik Gauting GmbH - Asklepios Fachkliniken München-Gauting | Gauting | 82131 | Germany | Details | ||
| Thoraxklinik am Universitätsklinikum Heidelberg | Heidelberg | 69126 | Germany | Details | ||
| Onkologische Schwerpunktpraxis | Heilbronn | 74072 | Germany | Details | ||
| Universitaetsklinikum Koeln | Koeln | 50937 | Germany | Details | ||
| Kliniken der Stadt Koeln gGmbH | Koeln | 51109 | Germany | Details | ||
| Bethanien Krankenhaus | Moers | 47441 | Germany | Details | ||
| Pius-Hospital Oldenburg | Oldenburg | 26121 | Germany | Details | ||
| Oncologianova GmbH | Recklinghausen | 45659 | Germany | Details | ||
| Orszagos Koranyi Tbc es Pulmonologiai Intezet | Budapest | H-1529 | Hungary | Details | ||
| Mátrai Gyógyintézet-Bronchológia | Gyöngyös | 3233 | Hungary | Details | ||
| Fejer Varmegyei Szent Gyorgy Egyetemi Oktatokorhaz | Szekesfehervar | 8000 | Hungary | Details | ||
| Markusovszky Egyetemi Oktatokorhaz | Szombathely | 9700 | Hungary | Details | ||
| Tudogyogyintezet Torokbalint | Torokbalint | 2045 | Hungary | Details | ||
| Basavatarakam Indo-American Hospital | Hyderabad | 500034 | India | Details | ||
| Tata Medical Center | Kolkata | 700160 | India | Details | ||
| Tata Memorial Hospital | Mumbai | 400012 | India | Details | ||
| HCG Manavta Cancer Centre | Nasik | 422002 | India | Details | ||
| Rajiv Gandhi Cancer Institute & Research Centre | New Delhi | 110085 | India | Details | ||
| Noble Hospital Pvt Ltd | Pune | 411013 | India | Details | ||
| Shaare Zedek Medical Center | Jerusalem | 91031 | Israel | Details | ||
| Hadassah Medical Center | Jerusalem | 9112001 | Israel | Details | ||
| Meir Medical Center | Kfar Saba | 44281 | Israel | Details | ||
| Rabin Medical Center | Petah Tikva | 49100 | Israel | Details | ||
| Tel-Aviv Sourasky Medical Center | Tel-Aviv | 6423906 | Israel | Details | ||
| A O U Sant Orsola Malpighi | Bologna | 40138 | Italy | Details | ||
| Azienda Ospedaliero Univ. Policlinico Gaspare Rodolico | Catania | 95123 | Italy | Details | ||
| Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori | Meldola | 47014 | Italy | Details | ||
| Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico | Milano | 20122 | Italy | Details | ||
| IRCCS Ospedale San Raffaele | Milano | 20132 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | 20133 | Italy | Details | ||
| San Gerardo Hospital | Monza | 20052 | Italy | Details | ||
| Ospedale S. Maria Delle Croci | Ravenna | 48121 | Italy | Details | ||
| Irccs Gemelli | Roma | 00168 | Italy | Details | ||
| Istituto Clinico Humanitas | Rozzano | 20089 | Italy | Details | ||
| Juntendo University Hospital | Bunkyo-Ku | 113-8431 | Japan | Details | ||
| Saitama Medical University International Medical Center | Hidaka | 350-1298 | Japan | Details | ||
| National Hospital Organization Himeji Medical Center | Himeji | 670-8520 | Japan | Details | ||
| Kansai Medical University Hospital | Hirakata | 573-1191 | Japan | Details | ||
| Kanazawa University Hospital | Kanazawa | 920-8641 | Japan | Details | ||
| National Cancer Center Hospital East | Kashiwa | 277 8577 | Japan | Details | ||
| Kishiwada City Hospital | Kishiwada | 596-8501 | Japan | Details | ||
| Kobe City Medical Center General Hospital | Kobe | 650-0047 | Japan | Details | ||
| Kurashiki Central Hospital | Kurashiki | 710-8602 | Japan | Details | ||
| Kurume University Hospital | Kurume | 830-0011 | Japan | Details | ||
| Matsusaka Municipal Hospital | Matsusaka | 515-8544 | Japan | Details | ||
| National Hospital Organization Nagoya Medical Center | Nagoya-shi | 460-0001 | Japan | Details | ||
| Aichi Cancer Center Hospital | Nagoya-Shi | 464-8681 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Kindai University Hospital | Osaka-Sayama-shi | 589-8511 | Japan | Details | ||
| Kitasato University Hospital | Sagamihara | 252-0375 | Japan | Details | ||
| Hokkaido University Hospital | Sapporo-shi | 060-8648 | Japan | Details | ||
| Iwate Medical University Hospital | Shiwa-gun | 028-3695 | Japan | Details | ||
| Shizuoka Cancer Center | Shizuoka | 411-8777 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Tokyo | 135 8550 | Japan | Details | ||
| Ehime University Hospital | Toon-shi | 791-0295 | Japan | Details | ||
| Wakayama Medical University Hospital | Wakayama | 641-8510 | Japan | Details | ||
| National Hospital Organization Yamaguchi Ube Medical Center | Yamaguchi | 755-0241 | Japan | Details | ||
| Inje University Haeundae Paik Hospital | Busan | 48108 | Korea, Republic of | Details | ||
| National Cancer Center | Gyeonggi-do | 10408 | Korea, Republic of | Details | ||
| GyeongSang National University Hospital | Gyeongsangnam-do | 52727 | Korea, Republic of | Details | ||
| Chonnam National University Hwasun Hospital | Jeollanam-do | 58128 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 13620 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Kangbuk Samsung Hospital | Seoul | 03181 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea Seoul St. Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Hospital Pulau Pinang | George Town | 10990 | Malaysia | Details | ||
| Hospital Sultan Ismail | Johor Bahru | 81100 | Malaysia | Details | ||
| Hospital Kuala Lumpur | Kuala Lumpur | 50586 | Malaysia | Details | ||
| University Malaya Medical Centre | Kuala Lumpur | 59100 | Malaysia | Details | ||
| Centro Oncológico de Chihuahua | Chihuahua | 31217 | Mexico | Details | ||
| Mexico Centre for Clinical Research, S.A. de C.V. | Ciudad de Mexico | 03100 | Mexico | Details | ||
| Médica Sur | Ciudad de Mexico | 14050 | Mexico | Details | ||
| Instituto Nacional de Cancerologia | Ciudad de Mexico | 14080 | Mexico | Details | ||
| Hospital Civil de Guadalajara Fray Antonio Alcalde | Guadalajara | 44280 | Mexico | Details | ||
| Health Pharma Professional Research | Mexico | 03100 | Mexico | Details | ||
| i Can Oncology Center | Monterrey | 64710 | Mexico | Details | ||
| Oncologia Integral Satelite | Naucalpan | 53100 | Mexico | Details | ||
| Centrum Onkologii im. Prof. F. Lukaszczyka | Bydgoszcz | 85-796 | Poland | Details | ||
| Uniwersyteckie Centrum Kliniczne | Gdansk | 80-214 | Poland | Details | ||
| Szpitale Pomorskie Sp z o o | Gdynia | 81-519 | Poland | Details | ||
| Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie | Olsztyn | 10-357 | Poland | Details | ||
| Private Specialist Hospitals - MedPolonia | Poznan | 60-693 | Poland | Details | ||
| Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
| Hosp. Cuf Descobertas | Lisboa | 1998-018 | Portugal | Details | ||
| Chlc - Hosp. Sto Antonio Dos Capuchos | Lisboa | G1R 2J6 | Portugal | Details | ||
| Centro Hospitalar Universitario do Porto, EPE | Porto | 4099-001 | Portugal | Details | ||
| Instituto Portugues de Oncologia | Porto | 4200-072 | Portugal | Details | ||
| Centro Hospitalar de Vila Nova de Gaia Espinho E P E | Vila Nova de Gaia | 4434 502 | Portugal | Details | ||
| Pan American Center for Oncology Trials LLC | Rio Piedras | 00935 | Puerto Rico | Details | ||
| Irkutsk Regional Oncology Dispensary | Irkutsk | 664035 | Russian Federation | Details | ||
| Moscow City Oncology Hospital № 62 | Krasnogorsk | 143423 | Russian Federation | Details | ||
| Krasnoyarsk Regional Oncology Dispensary | Krasnoyarsk | 660133 | Russian Federation | Details | ||
| Leningrad Regional Oncology Dispensary | Kuzmolovsky | 188663 | Russian Federation | Details | ||
| MCK | Moscow | 115533 | Russian Federation | Details | ||
| City Clinical Hospital #1 | Nalchik | 360000 | Russian Federation | Details | ||
| Nizhny Novgorod Regional Oncological Dispensary | Nizhniy Novgorod | 603000 | Russian Federation | Details | ||
| N.N. Petrov Research Institute Of Oncology | Saint Petersburg | 197758 | Russian Federation | Details | ||
| Leningrad Regional Clinical Hospital | Saint-Petersburg | 194291 | Russian Federation | Details | ||
| Oncology Medical Clinics AV Medical group | St-Petersburg | 196006 | Russian Federation | Details | ||
| Tomsk Cancer Research Institute | Tomsk | 634050 | Russian Federation | Details | ||
| Bashkir State Medical University | Ufa | 450083 | Russian Federation | Details | ||
| Yaroslavl Regional Clinical Oncology Hospital | Yaroslavl | 150054 | Russian Federation | Details | ||
| Hosp. Univ. A Coruna | A Coruña | 15006 | Spain | Details | ||
| Inst. Cat. D'Oncologia-Badalona | Badalona | 08916 | Spain | Details | ||
| Hosp. de La Santa Creu I Sant Pau | Barcelona | 08025 | Spain | Details | ||
| Hosp. Univ. Quiron Dexeus | Barcelona | 08028 | Spain | Details | ||
| Hosp. Univ. Vall D Hebron | Barcelona | 08035 | Spain | Details | ||
| Hosp. Univ. de Burgos | Burgos | 09003 | Spain | Details | ||
| Hosp. Gral. Univ. Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| Hosp. Univ. Ramon Y Cajal | Madrid | 28034 | Spain | Details | ||
| Hosp. Univ. 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Hosp. Univ. La Paz | Madrid | 28046 | Spain | Details | ||
| Hosp. Univ. Pta. de Hierro Majadahonda | Majadahonda | 28222 | Spain | Details | ||
| Hosp. Virgen de La Victoria | Málaga | 29010 | Spain | Details | ||
| Clinica Univ. de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hosp. Virgen Del Rocio | Seville | 41013 | Spain | Details | ||
| Hosp. Clinico Univ. Lozano Blesa | Zaragoza | 50009 | Spain | Details | ||
| Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung | 807 | Taiwan | Details | ||
| Chang Gung Medical Foundation | Kaohsiung | 833 | Taiwan | Details | ||
| Taipei Medical University Shuang Ho Hospital | New Taipei | 23561 | Taiwan | Details | ||
| Chung Shan Medical University Hospital | Taichung | 402 | Taiwan | Details | ||
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei City | 10002 | Taiwan | Details | ||
| Phramongkutklao Hospital and Medical College | Bangkok | 10400 | Thailand | Details | ||
| Siriraj Hospital | Bangkok | 10700 | Thailand | Details | ||
| Songklanagarind Hospital, Prince of Songkla University | Songkla | 90110 | Thailand | Details | ||
| Adana City Hospital | Adana | 01060 | Turkey | Details | ||
| Başkent University Medical Faculty Adana Application and Research Center | Adana | 01250 | Turkey | Details | ||
| Gazi University Hospital | Ankara | 6560 | Turkey | Details | ||
| Ankara Bilkent City Hospital | Ankara | 6800 | Turkey | Details | ||
| Trakya University Medical Faculty | Edirne | 22030 | Turkey | Details | ||
| Istanbul Universitesi Cerrahpasa Tip Fakultesi Ic Hastaliklari Anabilim Dali Medikal Onkoloji Bd | Istanbul | 34098 | Turkey | Details | ||
| Medipol Mega University Hospital | Istanbul | 34214 | Turkey | Details | ||
| Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi | Istanbul | 34722 | Turkey | Details | ||
| Izmir Medical Park Hospital | Izmir | 35580 | Turkey | Details | ||
| Dnipropetrovsk State Medical Academy, Dnipropetrovsk City Multifield Clinical Hospital # 4 | Dnipro | 49102 | Ukraine | Details | ||
| Medical Center 'Ok Clinic' of LLC 'International Institute of Clinical Studies' | Kyiv | 02091 | Ukraine | Details | ||
| National Cancer Institute | Kyiv | 03022 | Ukraine | Details | ||
| Edinburgh Cancer Centre Western General | Edinburgh | EH4 2XU | United Kingdom | Details | ||
| The Royal Marsden NHS Trust | London | SW3 6JJ | United Kingdom | Details | ||
| The Royal Marsden NHS Trust | Sutton | SM2 5PT | United Kingdom | Details |