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| NCT ID | NCT04543617 |
| Title | A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma (SKYSCRAPER-07) |
| Acronym | SKYSCRAPER-07 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NZL | ITA | GBR | FRA | ESP | DEU | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Compassionate Care Research Group Inc. Corona | Corona | California | 92879 | United States | Details | |
| Compassionate Cancer Care Medical Group, Inc | Corona | California | 92882 | United States | Details | |
| Compassionate Care Research Group Inc. Riverside | Riverside | California | 92501 | United States | Details | |
| Florida Cancer Specialists - Fort Myers (Broadway) | Fort Myers | Florida | 33901 | United States | Details | |
| Florida Cancer Specialist, North Region | Saint Petersburg | Florida | 33705 | United States | Details | |
| Mount Sinai Medical Center | New York | New York | 10029 | United States | Details | |
| Weill Cornell Medical College | New York | New York | 10065 | United States | Details | |
| Great Lakes Cancer Center | Williamsville | New York | 14221 | United States | Details | |
| MD Anderson Cancer Center; Oncology | Houston | Texas | 77030 | United States | Details | |
| Fundacion Favaloro | Buenos Aires | C1093AAS | Argentina | Details | ||
| Instituto de Investigaciones Metabolicas (Idim) | Ciudad Autonoma de Buenos Aires | C1012AAR | Argentina | Details | ||
| Centro Oncologico Riojano Integral (CORI) | La Rioja | F5300COE | Argentina | Details | ||
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Austin Health; Cancer Clinical Trial Centre | Heidelberg | Victoria | 3084 | Australia | Details | |
| St John of God Hospital; Bendat Cancer Centre | Subiaco | Western Australia | 6008 | Australia | Details | |
| Tiroler Landeskrankenanstalten Ges.M.B.H.; Innere Medizin Abt. Für Hämatologie & Onkologie | Innsbruck | 6020 | Austria | Details | ||
| Klinikum Klagenfurt am Wörthersee; Abteilung für Innere Medizin und Onkologie | Klagenfurt am Wörthersee | 9020 | Austria | Details | ||
| Ordensklinikum Linz Barmherzige Schwestern; Viszeralonkologisches Zentrum | Linz | 4010 | Austria | Details | ||
| AKH - Medizinische Universität Wien; Department for Internal Medicine I | Wien | 1090 | Austria | Details | ||
| UZ Antwerpen | Edegem | 2650 | Belgium | Details | ||
| UZ Leuven Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| CHU Sart-Tilman | Liège | 4000 | Belgium | Details | ||
| Anyang Tumor Hosptial | Anyang City | 455000 | China | Details | ||
| Cancer Hospital Chinese Academy of Medical Sciences. | Beijing | 100021 | China | Details | ||
| Affiliated Hospital of Bengbu Medical College | Bengbu | 233004 | China | Details | ||
| Hunan Cancer Hospital | Changsha CITY | 410013 | China | Details | ||
| Heping Hospital Affiliated to Changzhi Medical College | Changzhi City | 046000 | China | Details | ||
| Changzhou Cancer hospital | Changzhou | 213000 | China | Details | ||
| Sichuan Provincial Cancer Hospital | Chengdu | 610041 | China | Details | ||
| West China Hospital, Sichuan University | Chengdu | 610041 | China | Details | ||
| Chongqing Sanxia Central Hospital | Chongqing City | 404000 | China | Details | ||
| Chongqing Cancer Hospital | Chongqing | 400030 | China | Details | ||
| Fujian Cancer Hospital | Fuzhou | 350014 | China | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou City | 510663 | China | Details | ||
| Nanfang Hospital, Southern Medical University | Guangzhou | 510515 | China | Details | ||
| The First Affiliated Hospital of College of Medicine, Zhejiang University | Hangzhou | 310003 | China | Details | ||
| Affiliated Drum Tower Hospital of Nanjing University Medical School; Nanjing Shi | Jiangsu Sheng | 210008 | China | Details | ||
| Jieyang People's Hospital | Jieyang City | 522000 | China | Details | ||
| Shandong Cancer Hospital | Jinan | 250117 | China | Details | ||
| Affiliated Hospital of Jining Medical University | Jining | 272029 | China | Details | ||
| The First People's Hospital of Lian Yun Gang | Lianyungang | 222023 | China | Details | ||
| Lishui Central Hospital | Lishui City | 323000 | China | Details | ||
| The First Affiliated Hospital to Henan University of Science and Technology | Luoyang City | 471031 | China | Details | ||
| Jiangsu Cancer Hospital | Nanjing City | 211100 | China | Details | ||
| Fudan University Shanghai Cancer Center; Medical Oncology | Shanghai City | 201315 | China | Details | ||
| Shanghai Chest Hospital | Shanghai | 200000 | China | Details | ||
| Cancer Hospital of Shantou University Medical College | Shantou | 515041 | China | Details | ||
| Liaoning cancer Hospital & Institute | Shenyang | 110042 | China | Details | ||
| Cancer Hospital Chinese Academy of Medical Sciences Shenzhen Center | Shenzhen City | 518127 | China | Details | ||
| Hebei Medical University Fourth Hospital;(Tumor Hospital of Hebei Province) | Shijiazhuang | 050035 | China | Details | ||
| Tianjin Cancer Hospital | Tianjin | 300060 | China | Details | ||
| Wuhan Union Hospital Tongji Medical College, Huazhong University of Science and Technology | Wuhan City | 430022 | China | Details | ||
| Hubei Cancer Hospital | Wuhan | 430079 | China | Details | ||
| The First Affiliated Hospital of Xiamen University | Xiamen | 361003 | China | Details | ||
| Zhongshan Hospital Xiamen University | Xiamen | 361004 | China | Details | ||
| The First Affiliated Hospital of Xinxiang Medical University | Xinxiang City | 453000 | China | Details | ||
| The Affiliated Hospital of Xuzhou Medical College | Xuzhou | 221000 | China | Details | ||
| Subei People's Hospital of Jiangsu province; Respiratory | Yangzhou City | 225001 | China | Details | ||
| Zhejiang Cancer Hospital | Zhejiang | 310022 | China | Details | ||
| CHRU De Brest - Hopital Morvan - Institut De Cancerologie Et D'Hematologie | Brest | 29609 | France | Details | ||
| CHU Dijon Bourgogne Hôpital François Mitterand | Dijon | 21000 | France | Details | ||
| Hopital Claude Huriez; Medecine Interne Oncologie | Lille | 59037 | France | Details | ||
| CENTRE LEON BERARD; Département d?Hématologie et d?Oncologie | Lyon | 69373 | France | Details | ||
| Hopital Timone Adultes; Oncologie Digestive | Marseille | 13385 | France | Details | ||
| Centre Antoine Lacassagne | Nice | 06189 | France | Details | ||
| European Hospital Georges Pompidou (HEGP) | Paris | 75908 | France | Details | ||
| Hopital Du Haut-Leveque; Gastro-Enterologie | Pessac | 33604 | France | Details | ||
| Chu La Miletrie; Gastro Enterologie Endoscopies | Poitiers | 86021 | France | Details | ||
| Hopital Rangueil; Gastro Enterologie Et Nutrition | Toulouse | 31059 | France | Details | ||
| Universitätsklinikum Essen Klinik f.Strahlentherapie | Essen | 45122 | Germany | Details | ||
| Kliniken Essen-Mitte, Evang. Huyssens-Stiftung, Klinik für Internistische Onkologie / Haematologie | Essen | 45136 | Germany | Details | ||
| Klinik für Gastroenterologie und Gastrointestinale Onkologie der UMG | Göttingen | 37075 | Germany | Details | ||
| Universitaetsklinikum Leipzig | Leipzig | 04103 | Germany | Details | ||
| Med. Fak. d. Otto-von-Guericke-Universität; Unik. für Gastroenter., Hepat. und Infekt. | Magdeburg | 39120 | Germany | Details | ||
| Klinikum der Philipps-Universität Marburg | Marburg | 35032 | Germany | Details | ||
| Universitätsklinikum Klinik u.Poliklinik f.Strahlentherapie | Regensburg | 93053 | Germany | Details | ||
| Evgenidio Hospital "Agia Trias" | Athens | 115 28 | Greece | Details | ||
| Univ General Hosp Heraklion; Medical Oncology | Heraklion | 711 10 | Greece | Details | ||
| Euromedical General Clinic of Thessaloniki; Oncology Department | Thessaloniki | 546 45 | Greece | Details | ||
| Pécsi Tudományegyetem; Klinikai Központ Onkoterápiás Intézet | Pécs | 7623 | Hungary | Details | ||
| Szegedi Tudományegyetem; Onkoterápiás Klinika | Szeged | 6720 | Hungary | Details | ||
| Hadassah Ein Karem Hospital; Oncology Dept | Jerusalem | 9112000 | Israel | Details | ||
| Rambam Health Corporation; Oncology Institute | Rambam | 3525408 | Israel | Details | ||
| Tel Aviv Sourasky Medical Ctr; Oncology | Tel Aviv | 6423906 | Israel | Details | ||
| Università degli Studi della Campania Luigi Vanvitelli; Divsione Di Oncologia Medica | Napoli | Campania | 80131 | Italy | Details | |
| Ospedale Degli Infermi - Faenza; Oncologia Medica | Faenza | Emilia-Romagna | 48018 | Italy | Details | |
| AUSL-IRCCS di Reggio Emilia; Oncologia Medica | Reggio Emilia | Emilia-Romagna | 42124 | Italy | Details | |
| ASU FC S. M. DELLA MISERICORDIA; Oncologia | Udine | Friuli-Venezia Giulia | 33100 | Italy | Details | |
| Istituto Oncologico Veneto IRCCS | Padova | Veneto | 35128 | Italy | Details | |
| Aichi Cancer Center Hospital | Aichi | 464-8681 | Japan | Details | ||
| National Cancer Center Hospital East | Chiba | 277-8577 | Japan | Details | ||
| Hiroshima University Hospital | Hiroshima | 734-8551 | Japan | Details | ||
| Kobe University Hospital | Hyogo | 650-0017 | Japan | Details | ||
| Yokohama City University Medical Center | Kanagawa | 232-0024 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
| Tohoku University Hospital | Miyagi | 980-8574 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Osaka International Cancer Institute | Osaka | 541-8567 | Japan | Details | ||
| Osaka University Hospital | Osaka | 565-0871 | Japan | Details | ||
| Saitama Medical University International Medical Center | Saitama | 350-1298 | Japan | Details | ||
| Saitama Cancer Center | Saitama | 362-0806 | Japan | Details | ||
| Shizuoka Cancer Center | Shizuoka | 411-8777 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Tokyo | 135-8550 | Japan | Details | ||
| Keio University Hospital | Tokyo | 160-8582 | Japan | Details | ||
| International Cancer Institute (ICI) | Eldoret | 30100 | Kenya | Details | ||
| Aga Khan University Hospital | Nairobi | 00100 | Kenya | Details | ||
| Kyungpook National University Chilgok Hospital | Daegu | 41404 | Korea, Republic of | Details | ||
| Ajou University Medical Center | Gyeonggi-do | 16499 | Korea, Republic of | Details | ||
| Chonnam National University Hwasun Hospital | Jeollanam-do | 58128 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Korea University Guro Hospital | Seoul | 08308 | Korea, Republic of | Details | ||
| Centre Hospitalier Universitaire Hassan II | FES | 30000 | Morocco | Details | ||
| Centre Hospitalier Universitaire Mohamed VI; Oncologie-Hématologie | Marrakech | 40000 | Morocco | Details | ||
| Clinique specialise Menara; Oncology Medical | Marrakech | 40000 | Morocco | Details | ||
| Institut National D'oncologie Sidi Med Benabdellah; Oncolgy Medical | Rabat | 10100 | Morocco | Details | ||
| Tauranga Hospital, Clinical Trials Unit; BOP Clinical School | Tauranga | 3112 | New Zealand | Details | ||
| Centrum Onkologii;Im. Franciszka Lukaszczyka;Onkologii | Bydgoszcz | 85-796 | Poland | Details | ||
| CENTRUM ONKOLOGII ZIEMI LUBELSKIEJ IM. ?W. JANA Z DUKLI; II Oddzia? Onkologii Klinicznej | Lublin | 20-090 | Poland | Details | ||
| Szpital Kliniczny MSWiA z Warmi?sko-Mazurskim Centrum Onkologii; ZAK?.I O.KLINICZNY RADIOTERAPII | Olsztyn | 10-228 | Poland | Details | ||
| Wielkopolskie Centrum Onkologii im. Marii Sk?odowskiej-Curie; Odd. Onk. Klin. i Immunoonk. | Pozna? | 61-866 | Poland | Details | ||
| NIO im Marii Sklodowskiej-Curie; Klinika Onkologii i Radioterapii | Warszawa | 02-034 | Poland | Details | ||
| Dolno?l?skie Centrum Onkologii; Oddzia? Onkologii Klinicznej i Chemioterapii | Wroc?aw | 53-413 | Poland | Details | ||
| HUC; Servico de Oncologia Medica | Coimbra | 3000-075 | Portugal | Details | ||
| Centro Hospitalar do Porto ? Hospital de Santo António; Oncologia | Porto | 4099-001 | Portugal | Details | ||
| IPO do Porto; Servico de Oncologia Medica | Porto | 4200-072 | Portugal | Details | ||
| Krasnoyarsk Regional Oncology Dispensary n.a. Krizhanovsky; Chemotherapy | Krasnoyarsk | Krasnodar | 660133 | Russian Federation | Details | |
| Russian Oncology Research Center n.a. N.N. Blokhin Dpt of Clinical Pharmacology and Chemotherapy | Moscow | Moskovskaja Oblast | 115478 | Russian Federation | Details | |
| Scientific Research Institute n.a. N.N. Petrov | Saint Petersburg | Sankt Petersburg | 187758 | Russian Federation | Details | |
| SBEI HPE "The First St.Petersburg State Medical University n.a. acad. I.P.Pavlova"of MoH of RF | Sankt-peterburg | Sankt Petersburg | 197022 | Russian Federation | Details | |
| Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic | Kazan | Tatarstan | 420029 | Russian Federation | Details | |
| City Oncological Hospital | Izhevsk | Udmurtija | 426067 | Russian Federation | Details | |
| Limited Liability Company "RC Medical" | Novosibirsk | 630005 | Russian Federation | Details | ||
| Regional Oncology Dispensary | Tomsk | 634063 | Russian Federation | Details | ||
| Wits Donald Gordon Clinical Trial Site | Johannesburg | 2041 | South Africa | Details | ||
| Limpopo Cancer Research Institute | Polokwane | 0700 | South Africa | Details | ||
| Cancercare | Port Elizabeth | 6045 | South Africa | Details | ||
| Eugene Marais Hospital; Oncology | Pretoria | South Africa | Details | |||
| Hospital Univ. Central de Asturias | Oviedo | Asturias | 33006 | Spain | Details | |
| Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia | A Coruña | LA Coruña | 15006 | Spain | Details | |
| Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic I Provincial | Barcelona | 08036 | Spain | Details | ||
| Hospital Universitario Reina Sofia | Cordoba | 14008 | Spain | Details | ||
| Fundacion Jimenez Diaz; Servicio de Oncologia | Madrid | 28040 | Spain | Details | ||
| Hospital Regional Universitario Carlos Haya | Malaga | 29010 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Hospital La Fe | Valencia | Spain | Details | |||
| Inselspital Bern, Insel-Gruppe AG | Bern | 3010 | Switzerland | Details | ||
| UniversitätsSpital Zürich; Zentrum für Hämatologie und Onkologie, Klinik für Onkologie | Zürich | 8091 | Switzerland | Details | ||
| Chang Gung Medical Foundation - Kaohsiung; Oncology; Division of Hematology-Oncology | Kaoisung | 833 | Taiwan | Details | ||
| China Medical University Hospital; Oncology and Hematology | Taichung | 404 | Taiwan | Details | ||
| National Cheng Kung University Hospital; Oncology | Tainan | 00704 | Taiwan | Details | ||
| Chi-Mei Medical Centre; Hematology & Oncology | Tainan | 710 | Taiwan | Details | ||
| Taipei Veterans General Hospital; Department of Oncology | Taipei City | 112201 | Taiwan | Details | ||
| National Taiwan University Hospital; Oncology | Zhongzheng Dist. | 10048 | Taiwan | Details | ||
| Vajira Hospital | Bangkok | 10300 | Thailand | Details | ||
| Chulalongkorn Hospital; Medical Oncology | Bangkok | 10330 | Thailand | Details | ||
| Ramathibodi Hospital; Dept of Med.-Div. of Med. Onc | Bangkok | 10400 | Thailand | Details | ||
| Siriraj Hospital; Medical Oncology Unit | Bangkok | 10700 | Thailand | Details | ||
| Songklanagarind Hospital; Department of Oncology | Songkhla | 90110 | Thailand | Details | ||
| Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology | Adana | 01230 | Turkey | Details | ||
| Ankara University Faculty of Medicine Cebeci Hospital | Ankara | 06700 | Turkey | Details | ||
| Ankara City Hospital; Oncology | Ankara | 06800 | Turkey | Details | ||
| Ataturk University Medical Faculty Yakutiye Research Hospital Medical Oncology Department | Erzurum | 25240 | Turkey | Details | ||
| Gaziantep Univ. Med. Fac. | Gaziantep | 27310 | Turkey | Details | ||
| Istanbul University Cerrahpa?a-Cerrahpa?a Medical Faculty; Medikal Onkoloji Departmani | Istanbul | 34098 | Turkey | Details | ||
| Goztepe Prof.Dr. Suleyman Yalcin City Hospital; Clinical Oncology | Kadiköy | 34722 | Turkey | Details | ||
| Inonu University Faculty of Medicine Turgut Ozal Medical Center; Onkoloji, Elazig Yolu, | Malatya | 44280 | Turkey | Details | ||
| Van Yuzuncu Yil University Hospital; Medical Oncology | Van | 65000 | Turkey | Details | ||
| Municipal Noncommercial Institution Regional Center of Oncology | Kharkiv | Kharkiv Governorate | 61070 | Ukraine | Details | |
| Zhytomyr Regional Oncology Center | Zhytomyr | KIEV Governorate | 10007 | Ukraine | Details | |
| Vinnytsya Regional Clinical Oncology Dispensary | Vinnytsya | Podolia Governorate | 21029 | Ukraine | Details | |
| RCI Sumy Regional Clinical Oncological Dispensary | Sumy | 40005 | Ukraine | Details | ||
| Royal Bournemouth Hospital; Oncology | Bournemouth | BH7 7DW | United Kingdom | Details | ||
| Addenbrookes Hospital; Cambridge Cancer Trials Centre, S4 Box 279 | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Ninewells Hospital; Oncology | London | DD1 9SY | United Kingdom | Details | ||
| Royal Marsden Hospital - Fulham; Oncology Department | London | SW3 6JJ | United Kingdom | Details | ||
| Royal Marsden Hospital (Sutton) | Sutton | SM2 5PT | United Kingdom | Details | ||
| Clatterbridge Cancer Centre | Wirral | CH63 4JY | United Kingdom | Details | ||
| New Cross Hospital | Wolverhampton | WV10 0QP | United Kingdom | Details |