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| NCT ID | NCT04551053 |
| Title | To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Incyte Corporation |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DEU | BEL | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Sutter Health Alta Bates Summit Medical Center Absmc Alta Bates Summit Comprehensive Cancer Center | Berkeley | California | 94704 | United States | Details | |
| CCARE | Fresno | California | 93720 | United States | Details | |
| California Research Institute (Cri) | Los Angeles | California | 90027-6005 | United States | Details | |
| Emad Ibrahim Md Inc | Redlands | California | 92373 | United States | Details | |
| Scripps Clinic | San Diego | California | 92103 | United States | Details | |
| Coastal Integrated Cancer Care - Cicc | San Luis Obispo | California | 93401 | United States | Details | |
| Stamford Hospital - Medical Oncology Hematology | Stamford | Connecticut | 06904 | United States | Details | |
| Georgetown University | Washington | District of Columbia | 20057 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| Augusta University - Medical College of Georgia | Augusta | Georgia | 30912 | United States | Details | |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | United States | Details | |
| University of Kansas Hospital Authority | Westwood | Kansas | 66205 | United States | Details | |
| Tulane University | New Orleans | Louisiana | 70112 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States | Details | |
| Midamerica Cancer Care | Kansas City | Missouri | 64114 | United States | Details | |
| New Jersey Hematology Oncology Associates Llc | Brick | New Jersey | 08724 | United States | Details | |
| Morristown Medical Center - Atlantic Health System | Morristown | New Jersey | 07960 | United States | Details | |
| Montefiore Medical Center | Bronx | New York | 10467 | United States | Details | |
| Westchester Medical Center Advanced Oncology | Hawthorne | New York | 10532 | United States | Details | |
| Mount Sinai School of Medicine | New York | New York | 10029 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Advent Health Hendersonville Park Ridge Hospital Hendersonville | Clyde | North Carolina | 28721 | United States | Details | |
| Duke Cancer Center | Durham | North Carolina | 27710 | United States | Details | |
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| Oregon Health & Science University | Columbus | Ohio | 43210 | United States | Details | |
| Oregon Health & Science University | Portland | Oregon | 97239 | United States | Details | |
| Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Baptist Cancer Center | Memphis | Tennessee | 38120 | United States | Details | |
| Texas Oncology - Medical City Dallas | Dallas | Texas | 75230 | United States | Details | |
| Texas Oncology - Baylor Sammons Cancer Center | Dallas | Texas | 75246-2092 | United States | Details | |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390-8565 | United States | Details | |
| Renovatio Clinical | Houston | Texas | 77005 | United States | Details | |
| Kelsey Seybold Clinic | Houston | Texas | 77025 | United States | Details | |
| Providence Regional Medical Center Everett | Everett | Washington | 98201 | United States | Details | |
| Hanusch-Krankenhaus Wiener Gebietskrankenkasse | Wien | 01140 | Austria | Details | ||
| A.Z. St.-Jan A.V. | Brugge | 08000 | Belgium | Details | ||
| Jessa Ziekenhuis | Hasselt | 3500 | Belgium | Details | ||
| AZ Delta | Roeselare | 8800 | Belgium | Details | ||
| Chu Ucl Namur University Hospital Mont-Godinne | Yvoir | 05530 | Belgium | Details | ||
| Peking University People'S Hospital (Pkuph) - Institute of Hematology | Beijing SHI | 100044 | China | Details | ||
| Xuanwu Hospital Capital Medical University | Beijing | 100053 | China | Details | ||
| Peking University Third Hospital | Beijing | 100091 | China | Details | ||
| Peking University Third Hospital | Beijing | 100191 | China | Details | ||
| The First Hospital of Jilin University | Changchun | 130021 | China | Details | ||
| The First Peoples Hospital of Changzhou | Changzhou | 213003 | China | Details | ||
| Fujian Medical University Union Hospital | Fuzhou | 350001 | China | Details | ||
| Nanfang Hospital | Guangzhou | 510515 | China | Details | ||
| The First Affiliated Hospital of Zhejiang University | Hangzhou | 310003 | China | Details | ||
| Harbin Institute of Hematology and Oncology | Harbin | 150010 | China | Details | ||
| University of Science and Technology of China-First Affiliated Hospital (Anhui Provincial Hospital) | Hefei | 230022 | China | Details | ||
| The Affiliated Hospital of Inner Mongolia Medical University | Hohhot | 10050 | China | Details | ||
| Jinan Central Hospital | Jinan | 250013 | China | Details | ||
| The Second Affiliated Hospital of Kunming Medical University | Kunming | 650101 | China | Details | ||
| The First Hospital of Lanzhou University | Lanzhou | 730000 | China | Details | ||
| Lanzhou University Second Hospital | Lanzhou | 730030 | China | Details | ||
| Jiangxi Provincial of People Hospital | Nanchang | 330000 | China | Details | ||
| The First Affiliated Hospital of Nanchang University | Nanchang | 330006 | China | Details | ||
| Jiangsu Province Hospital | Nanjing | 210029 | China | Details | ||
| The Affiliated Hospital of Qingdao University | Qingdao | 266003 | China | Details | ||
| The First Hospital of China Medical University | Shenyang | 110001 | China | Details | ||
| Shenzhen University Hospital | Shenzhen | 518055 | China | Details | ||
| Tianjin Medical University General Hospital | Tianjin | 300052 | China | Details | ||
| Institute of Hematology and Hospital of Blood Diseases, Chinese Academy of Medical Sciences and Pek | Tianjin | 510080 | China | Details | ||
| Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology | Wuhan | 430022 | China | Details | ||
| Tongji Hospital Huazhong University of Science and Technology | Wuhan | 430030 | China | Details | ||
| The Second Affiliated Hospital of Xi an Jiaotong University | Xi'an | 710004 | China | Details | ||
| Yantai Yuhuangding Hospital | Yantai | 264000 | China | Details | ||
| Henan Provincial Peoples Hospital | Zhengzhou | 450003 | China | Details | ||
| Henan Cancer Hostipal | Zhengzhou | 450008 | China | Details | ||
| Helsinki University Central Hospital | Helsinki | FI-00029 | Finland | Details | ||
| Centre Hospitalier Universitaire Grenoble Alpes (Chu Grenoble Alpes) - Hopital Albert Michallon | La Tronche | 38700 | France | Details | ||
| Chu de Limoges | Limoges Cedex | 87042 | France | Details | ||
| CHU Limoges - Hopital Duputren | Limoges Cedex | 87042 | France | Details | ||
| Centre Hospitalier Universitaire de Nantes (Chu de Nantes) - Hotel-Dieu | Nantes | 44093 | France | Details | ||
| Chu Nimes | Nimes | 30900 | France | Details | ||
| Ap-Hp Groupe Hospitalier Saint-Louis Lariboisiere Fernand-Widal Site Saint Louis (Paris) | Paris | 75010 | France | Details | ||
| Hospital Saint Antoine | Paris | 75012 | France | Details | ||
| Hospices Civils de Lyon Centre Hospitalier Lyon Sud | Pierre-Benite | 69495 | France | Details | ||
| Institut Universitaire Du Cancer de Toulouse Oncopole | Toulouse | 31059 | France | Details | ||
| Chu Vandoeuvre-Les-Nancy Hopital Brabois | Vandoeuvre-les-nancy | 54500 | France | Details | ||
| Universitatsklinikum Bonn Aoer | Bonn | 53127 | Germany | Details | ||
| Universitaetsmedizin Greifswald | Greifswald | 17475 | Germany | Details | ||
| Universitatsklinikum Halle (Saale) | Halle (saale) | 06120 | Germany | Details | ||
| Universitaetsmedizin Rostock | Rostock | 18057 | Germany | Details | ||
| Semmelweis Egyetem | Budapest | 01088 | Hungary | Details | ||
| Markhot Ferenc Korhaz | Eger | 03300 | Hungary | Details | ||
| Petz Aladar County Teaching Hospital | Gyor | 09024 | Hungary | Details | ||
| Samson Assuta Ashdod University Hospital | Ashdod | 7747629 | Israel | Details | ||
| Rambam Health Care Campus | Haifa | 31999 | Israel | Details | ||
| Hadassah Hebrew University Medical Center Ein Karem Hadassah | Jerusalem | 91120 | Israel | Details | ||
| Kaplan Medical Center | Rehovot | 76100 | Israel | Details | ||
| Tel Aviv Sourasky Medical Center | Tel Aviv | 64239 | Israel | Details | ||
| Assuta Ramat Hahayal | Tel Aviv | 69710 | Israel | Details | ||
| Azienda Ospedaliera San Giuseppe Moscati | Avellino | 83100 | Italy | Details | ||
| Aou Policlinico Consorziale Di Bari | Bari | 70124 | Italy | Details | ||
| Lstituto Di Ematologia Lorenzo Ea.Seragnoli Universita Degli Studi Di Bologna - Policlinico S. Or | Bologna | 40138 | Italy | Details | ||
| Azienda Ospedaliera Di Rilievo Nazionale E Di Alta Specializzazione Garibaldi | Catania | 11111 | Italy | Details | ||
| University of Florence | Florence | 50134 | Italy | Details | ||
| Irccs Azienda Ospedaliera Universitaria San Martino | Genova | 16132 | Italy | Details | ||
| Fondazione Irccs Ca Granda Ospedale Maggiore | Milano | 20122 | Italy | Details | ||
| Universita Di Napoli Federico Ii | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Maggiore Della Carita Di Novara | Novara | 28100 | Italy | Details | ||
| Azienda Ospedaliera Ospedali Riuniti Villa Sofia - Cervello | Palermo | 90146 | Italy | Details | ||
| Ospedale S.Maria Della Misericordia | Perugia | 06156 | Italy | Details | ||
| Ospedale S.Maria Della Misericordia | Perugia | 6156 | Italy | Details | ||
| Presidio Ospedaliero Pescara | Pescara | 65124 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Pisana | Pisa | 56126 | Italy | Details | ||
| Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli | Reggio Calabria | 89133 | Italy | Details | ||
| Univ. Di Roma Facolta Di Armacia E Medicina | Roma | 00161 | Italy | Details | ||
| Policlinico Universitario Agostino Gemelli Universita Cattolica Del Sacro Cuore | Roma | 00168 | Italy | Details | ||
| Ospedale Sant. Eugenio | Roma | 144 | Italy | Details | ||
| Policlinico Universitario Agostino Gemelli Universita Cattolica Del Sacro Cuore | Rome | 00168 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Senese Policlinico Santa Maria Alle Scotte | Siena | 53100 | Italy | Details | ||
| Azienda Ospedaliera San Giuseppe Moscati | Taranto | 74123 | Italy | Details | ||
| Azienda Sanitaria Universitaria Friuli Centrale Asu Fc | Udine | 33100 | Italy | Details | ||
| A.O. Universitaria Ospedale Di Circolo E Fondazione Macchi | Varese | 21100 | Italy | Details | ||
| Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
| Japanese Red Cross Society Himeji Hospital | Himeji-shi | 670-8540 | Japan | Details | ||
| Kansai Medical University Hospital | Hirakata | 573-1191 | Japan | Details | ||
| Tokai University Hospital | Isehara | 2591193 | Japan | Details | ||
| Juntendo University Hospital | Izunokuni | 410-2211 | Japan | Details | ||
| Kagoshima University Hospital | Kagoshima | 890-8520 | Japan | Details | ||
| Hospital of the University of Occupation and Environmental Health | Kitakyushu-shi | 807-8556 | Japan | Details | ||
| Kobe City Medical Center General Hospital | Kobe-shi | 650-0047 | Japan | Details | ||
| Kumamoto Shinto General Hospital | Kumamoto-shi | 862-8655 | Japan | Details | ||
| University of Miyazaki Hospital | Miyazaki | 889-1692 | Japan | Details | ||
| Japanese Red Cross Nagoya Daini Hospital | Nagoya-shi | 453-8511 | Japan | Details | ||
| Ogaki Municipal Hospital | Ogaki | 5038502 | Japan | Details | ||
| Osaka Metropolitan University Hospital | Osaka | 545-8585 | Japan | Details | ||
| Dokkyo Medical University Saitama Medical Center | Saitama | 343-8555 | Japan | Details | ||
| Hokuyukai Sapporo Hokuyu Hospital | Sapporo | 003-0006 | Japan | Details | ||
| Juntendo University Hospital | Tokyo | 113-8431 | Japan | Details | ||
| Nippon Medical School Hospital | Tokyo | 113-8603 | Japan | Details | ||
| University of Yamanashi Hospital | Yamanashi | 409-3898 | Japan | Details | ||
| Pusan National University Yangsan Hospital | Busan | 49241 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea Seoul St. Mary?S Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Haukeland University Hospital | Bergen | 05021 | Norway | Details | ||
| Akershus University Hospital | Lorenskog | 01478 | Norway | Details | ||
| Pratia Hematologia Katowice | Katowice | 40-040 | Poland | Details | ||
| Pratia Hematologia Katowice | Katowice | 41-081 | Poland | Details | ||
| Samodzielny Publiczny Zoz Szpital Uniwersytecki W Krakowie | Krakow | 31-501 | Poland | Details | ||
| Samodzielny Publiczny Szpital Kliniczny Nr 1 | Lublin | 20-081 | Poland | Details | ||
| Institute of Hematology and Transfusion Medicine | Warszawa | 02-776 | Poland | Details | ||
| Spitalul Clinic Coltea - Clinica Hematologie | Bucharest, | 30171 | Romania | Details | ||
| Spitalul Clinic Judetean de Urgenta Targu Mures | Targu | 540139 | Romania | Details | ||
| Hospital General Unviersitario de Alicante | Alicante | 03010 | Spain | Details | ||
| Ico Hospital Germans Trias I Pujol | Badalona | 08916 | Spain | Details | ||
| Hospital Del Mar | Barcelona | 08003 | Spain | Details | ||
| Hospital General Universitario Vall D Hebron | Barcelona | 08035 | Spain | Details | ||
| Institut Catala Doncologia Ico - Hospital Duran I Reynals Location | Barcelona | 08908 | Spain | Details | ||
| Hospital Universitario Insular de Gran Canaria | Las Palmas de Gran Canaria | 35010 | Spain | Details | ||
| Hospital Universitario 12 de Octubre | Madrid | 24041 | Spain | Details | ||
| Fundacion Jimenez Diaz University Hospital | Madrid | 28040 | Spain | Details | ||
| Hospital General Universitario Morales Meseguer | Murcia | 30008 | Spain | Details | ||
| Hospital Universitario Virgen de La Arrixaca | Murcia | 30120 | Spain | Details | ||
| Hospital Clinico Universitario de Salamanca | Salamanca | 37007 | Spain | Details | ||
| Hospital Universitario Virgen Del Rocio | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitari I Politecnic La Fe | Valencia | 46000 | Spain | Details | ||
| Hospital Universitario Doctor Peset | Valencia | 46017 | Spain | Details | ||
| Hospital Universitario Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| Kaohsiung Chang Gung Memorial Hospital | Kaohsiung City | 83301 | Taiwan | Details | ||
| China Medical University Hospital | Taichung | 00404 | Taiwan | Details | ||
| National Cheng Kung University (Ncku) Hospital | Tainan | 00704 | Taiwan | Details | ||
| Baskent University Adana Hospital | Adana | 01250 | Turkey | Details | ||
| Gazi University Hospital Gazi University Faculty of Medicine | Ankara | 06500 | Turkey | Details | ||
| Istanbul Medipol Universitesi Ibagcilar Medipol Mega Universitesi Hastanesi | Istanbul | 34214 | Turkey | Details | ||
| Baskent University Istanbul Hospital | Istanbul | 34662 | Turkey | Details | ||
| Ege University Hospital | Izmir | 35040 | Turkey | Details | ||
| Ondokuz Mayis University Medicine Faculty | Samsun | 55200 | Turkey | Details | ||
| Grampian Health Board | Aberdeen | AB15 6RE | United Kingdom | Details | ||
| United Lincolnshire Hospitals | Boston | PE21 9QS | United Kingdom | Details | ||
| Gloucestershire Royal Hospital | Gloucester | GL1 3NN | United Kingdom | Details | ||
| University College London Hospitals Nhs Foundation Trust | London | NW1 2BU | United Kingdom | Details | ||
| James Cook University Hospital | Middlesbrough | TS4 3BW | United Kingdom | Details |