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| NCT ID | NCT04603807 |
| Title | A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | ITA | FRA | ESP |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Hospital de Cancer de Barretos | Active, not recruiting | Barretos | SP | 14784-400 | Brazil | Details |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | Recruiting | Sao Paulo | SP | 01246-000 | Brazil | Details |
| Beijing Union Hospital | Recruiting | Beijing | 100730 | China | Details | |
| Jilin Cancer Hospital | Active, not recruiting | Changchun | 132013 | China | Details | |
| Hunan Cancer Hospital | Active, not recruiting | Changsha CITY | 410013 | China | Details | |
| The Second Xiangya Hospital of Central South University | Active, not recruiting | Changsha | 410011 | China | Details | |
| Sichuan Provincial Cancer Hospital | Withdrawn | Chengdu | 610041 | China | Details | |
| West China Hospital, Sichuan University | Recruiting | Chengdu | 610041 | China | Details | |
| The First Affiliated Hospital of Guangzhou Medical University | Active, not recruiting | Guangzhou | 510120 | China | Details | |
| Harbin Medical University Cancer Hospital | Active, not recruiting | Harbin | 150081 | China | Details | |
| Affiliated Hospital of Jining Medical University | Recruiting | Jining | 272029 | China | Details | |
| Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School | Active, not recruiting | Nanjing City | 210008 | China | Details | |
| Guangxi Cancer Hospital of Guangxi Medical University | Active, not recruiting | Nanning | 530021 | China | Details | |
| Shanghai Pulmonary Hospital | Active, not recruiting | Shanghai | 200433 | China | Details | |
| Taihe Hospital of Hubei University of Medicine | Active, not recruiting | Shiyan | 442000 | China | Details | |
| Union Hospital Tongji Medical College Huazhong University of Science and Technology | Active, not recruiting | Wuhan City | 430022 | China | Details | |
| Clinical Hospital Centre Zagreb | Recruiting | Zagreb | 10000 | Croatia | Details | |
| Institut Bergonie; Pneumology | Recruiting | Bordeaux | 33076 | France | Details | |
| CHRU Lille | Recruiting | Lille | 59037 | France | Details | |
| Centre Leon Berard | Recruiting | Lyon | 69008 | France | Details | |
| Hopital Nord AP-HM | Recruiting | Marseille | 13015 | France | Details | |
| CHU Rennes - Hopital Pontchaillou | Recruiting | Rennes cedex 09 | 35033 | France | Details | |
| Hopital Larrey; Pneumologie | Recruiting | Toulouse | 31059 | France | Details | |
| Hopital Robert Schuman; Pneumologie | Recruiting | Vantoux | 57070 | France | Details | |
| Uoa Sotiria Hospital; Oncology | Recruiting | Athens | 115 27 | Greece | Details | |
| Metropolitan Hospital | Recruiting | Athens | 185 47 | Greece | Details | |
| University Hospital of Larissa;Department of Medical Oncology | Recruiting | Larissa | 411 10 | Greece | Details | |
| Euromedical General Clinic of Thessaloniki; Oncology Department | Recruiting | Thessaloniki | 546 45 | Greece | Details | |
| American Oncology Institute | Recruiting | Hyderabad | Andhra Pradesh | 500019 | India | Details |
| All India Institute Of Medical Sciences (AIIMS) | Recruiting | New Delhi | Delhi | 110029 | India | Details |
| MVR Cancer Centre and Research Institute | Recruiting | Kozhikode | Kerala | 673601 | India | Details |
| Mumbai Oncocare Centre | Active, not recruiting | Mumbai | Maharashtra | 400036 | India | Details |
| Mumbai Oncocare Center; Medical Oncology | Withdrawn | Mumbai | Maharashtra | 400056 | India | Details |
| Tata Medical Center; Department of Medical Oncology | Recruiting | Kolkata | WEST Bengal | 700160 | India | Details |
| Postgraduate Institute of Medical Education and Research | Recruiting | Chandigarh | 160012 | India | Details | |
| Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale | Recruiting | Napoli | Campania | 80131 | Italy | Details |
| IRCCS Istituto Regina Elena (IFO); Oncologia Medica B | Active, not recruiting | Roma | Lazio | 00144 | Italy | Details |
| Azienda Ospedaliera San Camillo Forlanini; U.O.C. Pneumologia Ad Indirizzo Oncologico 1 | Completed | Roma | Lazio | 00152 | Italy | Details |
| IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST); Oncologia Medica A | Recruiting | Genova | Liguria | 16132 | Italy | Details |
| Irccs Istituto Europeo di Oncologia (IEO); Divisione di Oncologia | Withdrawn | Milano | Lombardia | 20141 | Italy | Details |
| Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia | Recruiting | Milano | Lombardia | 20162 | Italy | Details |
| ASST DI MONZA; Oncologia Medica | Recruiting | Monza | Lombardia | 20900 | Italy | Details |
| Azienda Sanitaria Ospedaliera S Luigi Gonzaga; SSD Oncologia Polomonare (II PAD. IV PIANO) | Recruiting | Orbassano | Piemonte | 10043 | Italy | Details |
| Azienda Ospedaliera Universitaria Pisana - Ospedale Cisanello; Dipartimento Cardio Toraco Vascolare | Recruiting | Pisa | Toscana | 56124 | Italy | Details |
| IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Seconda | Active, not recruiting | Padova | Veneto | 35128 | Italy | Details |
| King Hussein Cancer Center | Active, not recruiting | Amman | 11941 | Jordan | Details | |
| Hospital Civil de Guadalajara Fray Antonio Alcalde | Recruiting | Guadalajara | Jalisco | 44280 | Mexico | Details |
| Health Pharma Professional Research | Recruiting | Cdmx | Mexico CITY (federal District) | 03100 | Mexico | Details |
| Superare; Centro de Infusion | Recruiting | Ciudad de México | Mexico CITY (federal District) | 06760 | Mexico | Details |
| Hospital Universitario; Dr. Jose E. Gonzalez | Recruiting | Monterrey | Nuevo LEON | 64460 | Mexico | Details |
| NKI/AvL | Active, not recruiting | Amsterdam | 1066 CX | Netherlands | Details | |
| UMC St Radboud | Active, not recruiting | Nijmegen | 6525 GA | Netherlands | Details | |
| Erasmus MC | Recruiting | Rotterdam | 3015 GD | Netherlands | Details | |
| Amethyst Cluj; Medical Oncology | Recruiting | Cluj County | 407280 | Romania | Details | |
| Emergency County Clinical Hospital Ploiesti; Medical oncology | Recruiting | Ploiesti | Romania | Details | ||
| Centrul de Oncologie Oncohelp | Recruiting | Timisoara | 300239 | Romania | Details | |
| AV Medical Ltd. | Recruiting | Sait-Petersburg Sankt Petersburg | Sankt Petersburg | 196006 | Russian Federation | Details |
| Univerzitna nemocnica Bratislava; Oddelenie Klinickej Onkologie, Klinika Pneumologie A Ftizeologie | Active, not recruiting | Bratislava | 826 06 | Slovakia | Details | |
| Vychodoslovensky onkologicky ustav | Recruiting | Košice | 040 01 | Slovakia | Details | |
| Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia | Recruiting | A Coruña | LA Coruña | 15006 | Spain | Details |
| Hospital del Mar; Servicio de Oncologia | Active, not recruiting | Barcelona | 08003 | Spain | Details | |
| Institut Catala d Oncologia Hospital Duran i Reynals | Recruiting | Barcelona | 08908 | Spain | Details | |
| Hospital Ramon y Cajal; Servicio de Oncologia | Recruiting | Madrid | 28034 | Spain | Details | |
| Hospital Regional Universitario Carlos Haya; Servicio de Oncologia | Recruiting | Malaga | 29011 | Spain | Details | |
| Karolinska Universitetssjukhuset, Solna; Kliniska prövningsenheten Z:4:01 | Recruiting | Stockholm | 171 76 | Sweden | Details | |
| Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology | Recruiting | Adana | 01230 | Turkey | Details | |
| Gazi University Medical Faculty, Oncology Hospital | Active, not recruiting | Ankara | 06500 | Turkey | Details | |
| Liv Hospital Ankara; Medical Oncology | Active, not recruiting | Ankara | 06680 | Turkey | Details | |
| Ege Uni Medical Faculty Hospital; Oncology Dept | Recruiting | Izmir | 35100 | Turkey | Details | |
| Inonu University Medical Faculty Turgut Ozal Medical Center Medical Oncology Department | Recruiting | Malatya | 44280 | Turkey | Details | |
| Ac?badem Maslak Hastanesi Büyükdere | Recruiting | Sar?yer/?stanbul | 34457 | Turkey | Details |