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NCT ID NCT04700072
Title Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)
Recruitment Recruiting
Gender both
Phase Phase Ib/II
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.



Lenvatinib + MK-1308A

Lenvatinib + Pembrolizumab

Age Groups: adult | senior
Covered Countries USA

Facility Status City State Zip Country Details
The Angeles Clinic and Research Institute ( Site 4009) Recruiting Los Angeles California 90025 United States Details
UCLA Hematology & Oncology ( Site 4004) Recruiting Los Angeles California 90095 United States Details
Providence Saint John's Health Center ( Site 4010) Recruiting Santa Monica California 90404 United States Details
University of Colorado, Anschutz Cancer Pavilion ( Site 4012) Recruiting Aurora Colorado 80045 United States Details
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ( Site 4022) Recruiting Baltimore Maryland 21231 United States Details
NYU Clinical Cancer Center ( Site 4002) Recruiting New York New York 10016 United States Details
Duke Cancer Institute ( Site 4005) Recruiting Durham North Carolina 27710 United States Details
Inova Schar Cancer Institute ( Site 4011) Recruiting Fairfax Virginia 22031 United States Details
Calvary Mater Newcastle ( Site 4404) Recruiting Waratah New South Wales 2298 Australia Details
Melanoma Institute Australia ( Site 4402) Recruiting Wollstonecraft New South Wales 2065 Australia Details
Hopital La Timone ( Site 4103) Recruiting Marseille Bouches-du-Rhone 13005 France Details
Institut Claudius Regaud ( Site 4105) Recruiting Toulouse cedex 9 Haute-Garonne 31059 France Details
Centre Hospitalier Lyon Sud ( Site 4102) Recruiting Pierre Benite Rhone 69495 France Details
HaEmek Medical Center ( Site 4703) Recruiting Afula 1834111 Israel Details
Rambam Health Care Campus-Oncology ( Site 4704) Recruiting Haifa 3109601 Israel Details
Hadassah Ein Karem Jerusalem ( Site 4702) Recruiting Jerusalem 9112001 Israel Details
Chaim Sheba Medical Center ( Site 4701) Recruiting Ramat Gan 5265601 Israel Details
Istituto Oncologico Veneto IRCCS ( Site 4355) Recruiting Padova Veneto 35128 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 4399) Recruiting Milano 20133 Italy Details
Istituto Europeo di Oncologia ( Site 4301) Recruiting Milano 20141 Italy Details
Istituto Nazionale Tumori Fondazione Pascale ( Site 4302) Recruiting Napoli 80131 Italy Details
Policlinico Le Scotte - A.O. Senese ( Site 4377) Recruiting Siena 53100 Italy Details
CHUV Centre Hospitalier Universitaire Vaudois ( Site 4602) Recruiting Lausanne Vaud 1011 Switzerland Details
Universitaetsspital Zuerich ( Site 4601) Recruiting Zurich 8058 Switzerland Details
*Shaded cells indicate that there was no data available from for the field