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| NCT ID | NCT04700072 |
| Title | Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The Angeles Clinic and Research Institute ( Site 4009) | Los Angeles | California | 90025 | United States | Details | |
| UCLA Hematology & Oncology ( Site 4004) | Los Angeles | California | 90095 | United States | Details | |
| Providence Saint John's Health Center ( Site 4010) | Santa Monica | California | 90404 | United States | Details | |
| University of Colorado, Anschutz Cancer Pavilion ( Site 4012) | Aurora | Colorado | 80045 | United States | Details | |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ( Site 4022) | Baltimore | Maryland | 21287 | United States | Details | |
| NYU Clinical Cancer Center ( Site 4002) | New York | New York | 10016 | United States | Details | |
| Duke Cancer Institute ( Site 4005) | Durham | North Carolina | 27710 | United States | Details | |
| Martha Morehouse Tower ( Site 4020) | Columbus | Ohio | 43221 | United States | Details | |
| Inova Schar Cancer Institute ( Site 4011) | Fairfax | Virginia | 22031 | United States | Details | |
| Calvary Mater Newcastle ( Site 4404) | Waratah | New South Wales | 2298 | Australia | Details | |
| Melanoma Institute Australia ( Site 4402) | Wollstonecraft | New South Wales | 2065 | Australia | Details | |
| Hopital La Timone ( Site 4103) | Marseille | Bouches-du-Rhone | 13005 | France | Details | |
| CHU de Bordeaux- Hopital Saint Andre ( Site 4108) | Bordeaux | Gironde | 33075 | France | Details | |
| Institut Claudius Regaud ( Site 4105) | Toulouse cedex 9 | Haute-Garonne | 31059 | France | Details | |
| Gustave Roussy ( Site 4101) | Villejuif | Ile-de-France | 94800 | France | Details | |
| Centre Hospitalier Lyon Sud ( Site 4102) | Pierre Benite | Rhone | 69495 | France | Details | |
| A.P.H. Paris, Hopital Saint Louis ( Site 4107) | Paris | 75010 | France | Details | ||
| HaEmek Medical Center ( Site 4703) | Afula | 1834111 | Israel | Details | ||
| Rambam Health Care Campus-Oncology ( Site 4704) | Haifa | 3109601 | Israel | Details | ||
| Hadassah Ein Karem Jerusalem ( Site 4702) | Jerusalem | 9112001 | Israel | Details | ||
| Rabin Medical Center-Oncology ( Site 4705) | Petah-Tikva | 4941492 | Israel | Details | ||
| Chaim Sheba Medical Center ( Site 4701) | Ramat Gan | 5265601 | Israel | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 4399) | Milano | 20133 | Italy | Details | ||
| Istituto Europeo di Oncologia ( Site 4301) | Milano | 20141 | Italy | Details | ||
| Istituto Nazionale Tumori Fondazione Pascale ( Site 4302) | Napoli | 80131 | Italy | Details | ||
| Istituto Oncologico Veneto IRCCS ( Site 4355) | Padova | 35128 | Italy | Details | ||
| Policlinico Le Scotte - A.O. Senese ( Site 4377) | Siena | 53100 | Italy | Details | ||
| CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 4865) | Port Elizabeth | Eastern Cape | 6055 | South Africa | Details | |
| LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 4861) | Pretoria | Gauteng | 0181 | South Africa | Details | |
| Sandton Oncology Medical Group (Pty) Ltd-Research ( Site 4863) | Sandton | Gauteng | 2196 | South Africa | Details | |
| Cape Town Oncology Trials ( Site 4864) | Cape Town | Western Cape | 7570 | South Africa | Details | |
| HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Sit | Barcelona | Cataluna | 08036 | Spain | Details | |
| Hospital Universitario Ramón y Cajal ( Site 4802) | Madrid | Madrid, Comunidad De | 28034 | Spain | Details | |
| Hôpitaux Universitaires de Genève (HUG)-Oncology ( Site 4603) | Genève | Geneve | 1211 | Switzerland | Details | |
| CHUV Centre Hospitalier Universitaire Vaudois ( Site 4602) | Lausanne | Vaud | 1011 | Switzerland | Details | |
| Universitaetsspital Zuerich ( Site 4601) | Zurich | 8058 | Switzerland | Details |