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NCT ID NCT04700124
Title Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304) (KEYNOTE-B15)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | ITA | FRA | ESP | DEU | CAN

Facility Status City State Zip Country Details
Mayo Clinic in Arizona - Phoenix ( Site 0043) Recruiting Phoenix Arizona 85054 United States Details
St Joseph Heritage Healthcare-Oncology ( Site 0035) Completed Fullerton California 92835 United States Details
UCLA Hematology/Oncology - Westwood (Building 200 Suite 140)-Department of Urology/Institute of Uro Recruiting Los Angeles California 90095 United States Details
University of California San Francisco ( Site 0010) Recruiting San Francisco California 94158 United States Details
Stanford University ( Site 0023) Recruiting Stanford California 94305 United States Details
University of Colorado, Anschutz Cancer Pavilion ( Site 0009) Recruiting Aurora Colorado 80045 United States Details
UF Health ( Site 0031) Recruiting Gainesville Florida 32608 United States Details
Indiana University Melvin and Bren Simon Cancer Center ( Site 0050) Recruiting Indianapolis Indiana 46202 United States Details
University of Iowa Hospital and Clinics ( Site 0029) Recruiting Iowa City Iowa 52242 United States Details
University of Louisville, James Graham Brown Cancer Center ( Site 0022) Recruiting Louisville Kentucky 40202 United States Details
Icahn School of Medicine at Mount Sinai ( Site 0011) Recruiting New York New York 10029 United States Details
White Plains Hospital ( Site 0039) Recruiting White Plains New York 10601 United States Details
Duke University Medical Center ( Site 0017) Recruiting Durham North Carolina 27710 United States Details
Wake Forest Baptist Health ( Site 0014) Recruiting Winston-Salem North Carolina 27157 United States Details
Oregon Health and Science University ( Site 0028) Recruiting Portland Oregon 97239 United States Details
MidLantic Urology ( Site 0002) Recruiting Bala-Cynwyd Pennsylvania 19004 United States Details
Saint Francis Cancer Center ( Site 0008) Recruiting Greenville South Carolina 29607 United States Details
The University of Tennessee Medical Center ( Site 0034) Completed Knoxville Tennessee 37920 United States Details
UT Southwestern Medical Center ( Site 0003) Recruiting Dallas Texas 75390 United States Details
Houston Methodist Urology Associates ( Site 0033) Recruiting Houston Texas 77030 United States Details
Urology of San Antonio ( Site 0020) Recruiting San Antonio Texas 78229 United States Details
University of Wisconsin Hospital and Clinics ( Site 0037) Recruiting Madison Wisconsin 53792 United States Details
Mater Hospital Brisbane ( Site 1257) Active, not recruiting South Brisbane Queensland 4101 Australia Details
Lyell McEwin Hospital ( Site 1252) Recruiting Elizabeth Vale South Australia 5112 Australia Details
Frankston Hospital-Oncology and Haematology ( Site 1258) Recruiting Frankston Victoria 3199 Australia Details
MHAT "Uni Hospital" OOD ( Site 1154) Recruiting Panagyurishte Pazardzhik 4500 Bulgaria Details
Complex Oncology Center Plovdiv ( Site 1151) Recruiting Plovdiv 4000 Bulgaria Details
MHAT Central Onco Hospital OOD ( Site 1158) Recruiting Plovdiv 4000 Bulgaria Details
MHAT Serdika ( Site 1152) Recruiting Sofia 1632 Bulgaria Details
BC Cancer - Vancouver Center ( Site 0110) Recruiting Vancouver British Columbia V5Z 4E6 Canada Details
Moncton Hospital ( Site 0107) Recruiting Moncton New Brunswick E1C 6Z8 Canada Details
Ottawa Hospital Research Institute ( Site 0109) Recruiting Ottawa Ontario K1H 8L6 Canada Details
Jewish General Hospital ( Site 0106) Recruiting Montreal Quebec H3T 1E2 Canada Details
SUN YAT-SEN UNIVERSITY CANCER CENTRE ( Site 1406) Recruiting Guangzhou Guangdong 510060 China Details
Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1413) Recruiting Guangzhou Guangdong 510120 China Details
Hunan Cancer Hospital ( Site 1403) Recruiting Changsha Hunan 410013 China Details
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S Recruiting Nanjing Jiangsu 210000 China Details
Nantong Tumor Hospital-Urology ( Site 1405) Recruiting Nantong Jiangsu 226361 China Details
Fudan University Shanghai Cancer Center-Urology department ( Site 1401) Recruiting Shanghai Shanghai 200032 China Details
Renji Hospital Shanghai Jiao Tong University School of Medicine ( Site 1402) Recruiting Shanghai Shanghai 200127 China Details
Fakultni nemocnice u sv. Anny v Brne ( Site 0253) Recruiting Brno Jihomoravsky Kraj 656 91 Czechia Details
Fakultni nemocnice Hradec Kralove-Klinika onkologie a radioterapie ( Site 0254) Recruiting Hradec Kralove 500 05 Czechia Details
Fakultni Nemocnice Olomouc ( Site 0251) Recruiting Olomouc 779 00 Czechia Details
Fakultni Thomayerova nemocnice ( Site 0252) Recruiting Praha 4 140 59 Czechia Details
CHU La Timone ( Site 0456) Recruiting Marseille Bouches-du-Rhone 13005 France Details
CHU Jean Minjoz ( Site 0453) Recruiting Besancon Doubs 25000 France Details
CHU de Brest -Site Hopital Morvan ( Site 0461) Recruiting Brest Finistere 29200 France Details
Institut Universitaire du Cancer Toulouse - Oncopole ( Site 0455) Recruiting Toulouse Haute-Garonne 31059 France Details
CHU Limoges Hopital Dupuytren ( Site 0459) Recruiting Limoges Haute-Vienne 87042 France Details
Gustave Roussy ( Site 0467) Recruiting Villejuif Ile-de-France 94800 France Details
Centre Hospitalier Regional du Orleans ( Site 0463) Recruiting Orleans Loiret 45067 France Details
Polyclinique du Bois ( Site 0458) Recruiting Lille Nord 59000 France Details
Hopital Diaconesses Croix Saint Simon ( Site 0465) Recruiting Paris 75020 France Details
Universitaetsklinikum Freiburg ( Site 0512) Recruiting Freiburg Baden-Wurttemberg 79106 Germany Details
Universitaetsklinik fuer Urologie ( Site 0501) Recruiting Tuebingen Baden-Wurttemberg 72076 Germany Details
Caritas Krankenhaus St. Josef ( Site 0502) Recruiting Regensburg Bayern 93053 Germany Details
Kath. Krankenhaus Marienhospital. Universitaetsklinik ( Site 0511) Recruiting Herne Nordrhein-Westfalen 44625 Germany Details
Universitaetsklinikum Muenster ( Site 0516) Recruiting Muenster Nordrhein-Westfalen 48149 Germany Details
Krankenhaus Martha Maria Halle-Doelau ( Site 0507) Recruiting Halle Sachsen-Anhalt 06120 Germany Details
Universitaetsklinikum Carl Gustav Carus ( Site 0509) Recruiting Dresden Sachsen 01307 Germany Details
Vivantes Klinikum Am Urban ( Site 0519) Recruiting Berlin 10967 Germany Details
UNIVERSITY HOSPITAL OF PATRAS-DIVISION OF ONCOLOGY ( Site 0305) Recruiting Patras Achaia 26504 Greece Details
General Hospital of Athens "Alexandra" ( Site 0303) Recruiting Athens Attiki 115 28 Greece Details
Athens Medical Center ( Site 0304) Recruiting Athens Attiki 151 25 Greece Details
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 0301) Recruiting Chaidari Attiki 124 62 Greece Details
University General Hospital of Larissa ( Site 0302) Recruiting Larissa Thessalia 411 10 Greece Details
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ ( Site 1010) Recruiting Szeged Csongrad 6720 Hungary Details
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház ( Site 1002) Recruiting Szolnok Jasz-Nagykun-Szolnok 5004 Hungary Details
Debreceni Egyetem Klinikai Kozpont ( Site 1006) Recruiting Debrecen 4032 Hungary Details
Rambam Health Care Campus-Oncology ( Site 0751) Recruiting Haifa 3109601 Israel Details
Hadassah Medical Center-Oncology ( Site 0757) Recruiting Jerusalem 9112001 Israel Details
Meir Medical Center-oncology ( Site 0754) Recruiting Kfar Saba 4428164 Israel Details
Rabin Medical Center-Oncology ( Site 0752) Recruiting Petah-Tikva 4941492 Israel Details
Sheba Medical Center-ONCOLOGY ( Site 0753) Recruiting Ramat Gan 5262100 Israel Details
Sourasky Medical Center-Oncology ( Site 0755) Recruiting Tel Aviv 64239 Israel Details
Yitzhak Shamir Medical Center-Oncology ( Site 0756) Recruiting Zerifin 70300 Israel Details
Presidio Ospedaliero Santa Maria delle Grazie ( Site 0599) Recruiting Pozzuoli Napoli 80078 Italy Details
AOU San Luigi Gonzaga di Orbassano ( Site 0595) Recruiting Orbassano Torino 10043 Italy Details
Istituto Oncologico Veneto IRCCS-Oncologia Medica 1 ( Site 0600) Recruiting Padova Veneto 35128 Italy Details
Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento ( Site 0598) Recruiting Verona Veneto 37126 Italy Details
Ospedali Riuniti Umberto I GM Lancis G Salesi ( Site 0593) Recruiting Ancona 60126 Italy Details
Ospedale Cannizzaro ( Site 0590) Recruiting Catania 95126 Italy Details
IRCCS Ospedale San Raffaele ( Site 0596) Recruiting Milano 20132 Italy Details
Nagoya University Hospital ( Site 1512) Recruiting Nagoya Aichi 466-8560 Japan Details
Hirosaki University Hospital ( Site 1501) Recruiting Hirosaki Aomori 036-8563 Japan Details
University of Tsukuba Hospital ( Site 1502) Recruiting Tsukuba Ibaraki 305-8576 Japan Details
Kanazawa University Hospital ( Site 1509) Recruiting Kanazawa Ishikawa 920-8641 Japan Details
Yokohama City University Medical Center ( Site 1508) Completed Yokohama Kanagawa 232-0024 Japan Details
Kanagawa Cancer Center ( Site 1507) Recruiting Yokohama Kanagawa 241-8515 Japan Details
Tohoku University Hospital ( Site 1503) Recruiting Sendai Miyagi 980-8574 Japan Details
Hamamatsu University Hospital ( Site 1511) Recruiting Hamamatsu Shizuoka 431-3192 Japan Details
Gifu University Hospital ( Site 1513) Recruiting Gifu 501-1194 Japan Details
Nagasaki University Hospital ( Site 1517) Recruiting Nagasaki 852-8510 Japan Details
Okayama University Hospital ( Site 1516) Recruiting Okayama 7008558 Japan Details
Osaka International Cancer Institute ( Site 1514) Recruiting Osaka 5418567 Japan Details
Osaka Metropolitan University Hospital ( Site 1515) Recruiting Osaka 545-8586 Japan Details
Tokyo Medical and Dental University Hospital ( Site 1505) Recruiting Tokyo 113-8519 Japan Details
Keio University Hospital ( Site 1504) Recruiting Tokyo 160-8582 Japan Details
Toyama University Hospital ( Site 1510) Recruiting Toyama 930-0194 Japan Details
Chonnam National University Hwasun Hospital ( Site 1353) Recruiting Jeollanam-do Jeonranamdo 58128 Korea, Republic of Details
Seoul National University Bundang Hospital ( Site 1355) Recruiting Gyeonggi-do Kyonggi-do 13620 Korea, Republic of Details
Asan Medical Center ( Site 1352) Recruiting Songpagu Seoul 05505 Korea, Republic of Details
Kyungpook National University Chilgok Hospital ( Site 1354) Recruiting Daegu Taegu-Kwangyokshi 41404 Korea, Republic of Details
Gachon University Gil Medical Center ( Site 1356) Recruiting Incheon 21565 Korea, Republic of Details
Korea University Anam Hospital ( Site 1357) Recruiting Seoul 02841 Korea, Republic of Details
Seoul National University Hospital ( Site 1351) Recruiting Seoul 03080 Korea, Republic of Details
University Malaya Medical Centre ( Site 0352) Recruiting Lembah Pantai Kuala Lumpur 59100 Malaysia Details
Hospital Pulau Pinang ( Site 0355) Recruiting George Town Pulau Pinang 10990 Malaysia Details
Sarawak General Hospital ( Site 0351) Recruiting Kuching Sarawak 93586 Malaysia Details
Sunway Medical Centre ( Site 0353) Recruiting Petaling Jaya Selangor 47500 Malaysia Details
THE MEDICAL CITY ILOILO-The Medical City Iloilo - Clinical and Translational Research Institute-Ilo Recruiting Iloilo City Iloilo 5000 Philippines Details
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu ( Site 1058) Recruiting Wrocław Dolnoslaskie 50-556 Poland Details
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1057) Recruiting Siedlce Mazowieckie 08-110 Poland Details
Narodowy Instytut Onkologii ( Site 1051) Recruiting Warszawa Mazowieckie 02-781 Poland Details
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1053) Recruiting Przemysl Podkarpackie 37-700 Poland Details
Clinical Research Center Medic-R ( Site 1061) Recruiting Poznan Wielkopolskie 61-731 Poland Details
Szpital Wojewodzki im. Mikolaja Kopernika ( Site 1055) Recruiting Koszalin Zachodniopomorskie 75-581 Poland Details
Centro Hospitalar e Universitario de Coimbra ( Site 0406) Recruiting Coimbra 3000-075 Portugal Details
Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE ( Site 0409) Recruiting Lisboa 1099-023 Portugal Details
CHLO, EPE - Hospital de Sao Francisco Xavier ( Site 0401) Recruiting Lisboa 1449-005 Portugal Details
Hospital Geral de Santo Antonio ( Site 0408) Recruiting Porto 4099-001 Portugal Details
Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1102) Recruiting Cluj Napoca Cluj 400015 Romania Details
Cardiomed SRL Cluj-Napoca ( Site 1101) Recruiting Cluj-Napoca Cluj 400015 Romania Details
Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1103) Recruiting Cluj-Napoca Cluj 400015 Romania Details
SC Radiotherapy Center Cluj SRL ( Site 1108) Recruiting Comuna Floresti Cluj 407280 Romania Details
S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 1107) Recruiting Craiova Dolj 200542 Romania Details
Policlinica Oncomed SRL ( Site 1106) Recruiting Timisoara Timis 300239 Romania Details
SC Focus Lab Plus SRL ( Site 1104) Recruiting Bucuresti 022548 Romania Details
Altay Regional Oncology Dispensary ( Site 0851) Suspended Barnaul Altayskiy Kray 656045 Russian Federation Details
National Medical Research Radiology Centre ( Site 0869) Suspended Obninsk Kaluzskaja Oblast 249036 Russian Federation Details
National Medical Research Centre of Oncology named after N.N. Blokhin ( Site 0865) Suspended Moscow Moskva 115230 Russian Federation Details
First Moscow State Medical University n.a. I.M.Sechenov ( Site 0871) Suspended Moscow Moskva 119991 Russian Federation Details
Volga District Medical Center ( Site 0876) Suspended Nizhny Novgorod Nizhegorodskaya Oblast 603074 Russian Federation Details
St.Petersburg Clinical Hospital RAS ( Site 0864) Suspended Saint Petersburg Sankt-Peterburg 194017 Russian Federation Details
St.Petersburg State Medical Univ. n.a. acad. I.P.Pavlov ( Site 0856) Suspended Saint Petersburg Sankt-Peterburg 197101 Russian Federation Details
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 0852) Suspended Saint Petersburg Sankt-Peterburg 197758 Russian Federation Details
Sverdlovsk Regional Oncology Hospital ( Site 0867) Suspended Ekaterinburg Sverdlovskaya Oblast 620036 Russian Federation Details
Sverdlovsky Regional Clinical hospital #1 ( Site 0868) Suspended Ekaterinburg Sverdlovskaya Oblast 620102 Russian Federation Details
Volgograd Regional Uronephrological Center ( Site 0870) Suspended Volzhsky Volgogradskaya Oblast 404120 Russian Federation Details
Tan Tock Seng Hospital ( Site 0704) Recruiting Singapore Central Singapore 398442 Singapore Details
Wits Clinical Research ( Site 0603) Recruiting Johannesburg Gauteng 2193 South Africa Details
Steve Biko Academic Hospital ( Site 0601) Recruiting Pretoria Gauteng 0002 South Africa Details
Groote Schuur Hospital ( Site 0602) Recruiting Cape Town Western Cape 7925 South Africa Details
Hospital Universitario Central de Asturias ( Site 0654) Recruiting Oviedo Asturias 33011 Spain Details
Hospital Germans Trias i Pujol. ICO de Badalona ( Site 0658) Recruiting Badalona Barcelona 08916 Spain Details
Xarxa Assistencial Universitaria Manresa ( Site 0655) Recruiting Manresa Barcelona 08243 Spain Details
Hospital Universitari de Girona Doctor Josep Trueta ( Site 0653) Recruiting Girona Gerona 17007 Spain Details
CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 0660) Recruiting Santiago de Compostela La Coruna 15706 Spain Details
Hospital Universitario Insular de Gran Canaria ( Site 0657) Recruiting Las Palmas de Gran Canaria Las Palmas 35001 Spain Details
Fundación Instituto Valenciano de Oncología-Oncologico ( Site 0662) Recruiting Valencia Valenciana, Comunitat 46009 Spain Details
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0661) Recruiting Barcelona 08035 Spain Details
Hospital Clinico Universitario San Carlos de Madrid ( Site 0651) Recruiting Madrid 28040 Spain Details
Hospital Virgen del Rocio ( Site 0659) Recruiting Sevilla 41013 Spain Details
China Medical University Hospital ( Site 1202) Recruiting Taichung 404332 Taiwan Details
Taipei Veterans General Hospital ( Site 1201) Recruiting Taipei 11217 Taiwan Details
I.I. Mechnykov Dnipropetrovsk Regional Clinical Hospital ( Site 0959) Suspended Dnipro Dnipropetrovska Oblast 49005 Ukraine Details
MI Clinical oncology dispensary of Dnipropetrovsk regional council ( Site 0954) Suspended Dnipro Dnipropetrovska Oblast 49055 Ukraine Details
Regional Clinical Center of Urology and Nephrology n.a. V.I. Shapoval ( Site 0952) Suspended Kharkiv Kharkivska Oblast 61037 Ukraine Details
MNPE Regional Center of Oncology ( Site 0955) Suspended Kharkiv Kharkivska Oblast 61070 Ukraine Details
Municipal Non-profit Enterprise of Kharkiv Regional Council RCSDRPP ( Site 0965) Suspended Kharkiv Kharkivska Oblast 61166 Ukraine Details
Lviv Oncology Regional Treatment and Diagnostic Center ( Site 0960) Suspended Lviv Lvivska Oblast 79031 Ukraine Details
Zhytomyr Regional Oncology Center ( Site 0961) Suspended Zhytomyr Zhytomyrska Oblast 10002 Ukraine Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field