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| NCT ID | NCT04700124 |
| Title | Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304) (KEYNOTE-B15) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | DEU | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic in Arizona - Phoenix ( Site 0043) | Recruiting | Phoenix | Arizona | 85054 | United States | Details |
| St Joseph Heritage Healthcare-Oncology ( Site 0035) | Completed | Fullerton | California | 92835 | United States | Details |
| UCLA Hematology/Oncology - Westwood (Building 200 Suite 140)-Department of Urology/Institute of Uro | Recruiting | Los Angeles | California | 90095 | United States | Details |
| University of California San Francisco ( Site 0010) | Recruiting | San Francisco | California | 94158 | United States | Details |
| Stanford University ( Site 0023) | Recruiting | Stanford | California | 94305 | United States | Details |
| University of Colorado, Anschutz Cancer Pavilion ( Site 0009) | Recruiting | Aurora | Colorado | 80045 | United States | Details |
| UF Health ( Site 0031) | Recruiting | Gainesville | Florida | 32608 | United States | Details |
| Indiana University Melvin and Bren Simon Cancer Center ( Site 0050) | Recruiting | Indianapolis | Indiana | 46202 | United States | Details |
| University of Iowa Hospital and Clinics ( Site 0029) | Recruiting | Iowa City | Iowa | 52242 | United States | Details |
| University of Louisville, James Graham Brown Cancer Center ( Site 0022) | Recruiting | Louisville | Kentucky | 40202 | United States | Details |
| Icahn School of Medicine at Mount Sinai ( Site 0011) | Recruiting | New York | New York | 10029 | United States | Details |
| White Plains Hospital ( Site 0039) | Recruiting | White Plains | New York | 10601 | United States | Details |
| Duke University Medical Center ( Site 0017) | Recruiting | Durham | North Carolina | 27710 | United States | Details |
| Wake Forest Baptist Health ( Site 0014) | Recruiting | Winston-Salem | North Carolina | 27157 | United States | Details |
| Oregon Health and Science University ( Site 0028) | Recruiting | Portland | Oregon | 97239 | United States | Details |
| MidLantic Urology ( Site 0002) | Recruiting | Bala-Cynwyd | Pennsylvania | 19004 | United States | Details |
| Saint Francis Cancer Center ( Site 0008) | Recruiting | Greenville | South Carolina | 29607 | United States | Details |
| The University of Tennessee Medical Center ( Site 0034) | Completed | Knoxville | Tennessee | 37920 | United States | Details |
| UT Southwestern Medical Center ( Site 0003) | Recruiting | Dallas | Texas | 75390 | United States | Details |
| Houston Methodist Urology Associates ( Site 0033) | Recruiting | Houston | Texas | 77030 | United States | Details |
| Urology of San Antonio ( Site 0020) | Recruiting | San Antonio | Texas | 78229 | United States | Details |
| University of Wisconsin Hospital and Clinics ( Site 0037) | Recruiting | Madison | Wisconsin | 53792 | United States | Details |
| Mater Hospital Brisbane ( Site 1257) | Active, not recruiting | South Brisbane | Queensland | 4101 | Australia | Details |
| Lyell McEwin Hospital ( Site 1252) | Recruiting | Elizabeth Vale | South Australia | 5112 | Australia | Details |
| Frankston Hospital-Oncology and Haematology ( Site 1258) | Recruiting | Frankston | Victoria | 3199 | Australia | Details |
| MHAT "Uni Hospital" OOD ( Site 1154) | Recruiting | Panagyurishte | Pazardzhik | 4500 | Bulgaria | Details |
| Complex Oncology Center Plovdiv ( Site 1151) | Recruiting | Plovdiv | 4000 | Bulgaria | Details | |
| MHAT Central Onco Hospital OOD ( Site 1158) | Recruiting | Plovdiv | 4000 | Bulgaria | Details | |
| MHAT Serdika ( Site 1152) | Recruiting | Sofia | 1632 | Bulgaria | Details | |
| BC Cancer - Vancouver Center ( Site 0110) | Recruiting | Vancouver | British Columbia | V5Z 4E6 | Canada | Details |
| Moncton Hospital ( Site 0107) | Recruiting | Moncton | New Brunswick | E1C 6Z8 | Canada | Details |
| Ottawa Hospital Research Institute ( Site 0109) | Recruiting | Ottawa | Ontario | K1H 8L6 | Canada | Details |
| Jewish General Hospital ( Site 0106) | Recruiting | Montreal | Quebec | H3T 1E2 | Canada | Details |
| SUN YAT-SEN UNIVERSITY CANCER CENTRE ( Site 1406) | Recruiting | Guangzhou | Guangdong | 510060 | China | Details |
| Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1413) | Recruiting | Guangzhou | Guangdong | 510120 | China | Details |
| Hunan Cancer Hospital ( Site 1403) | Recruiting | Changsha | Hunan | 410013 | China | Details |
| Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S | Recruiting | Nanjing | Jiangsu | 210000 | China | Details |
| Nantong Tumor Hospital-Urology ( Site 1405) | Recruiting | Nantong | Jiangsu | 226361 | China | Details |
| Fudan University Shanghai Cancer Center-Urology department ( Site 1401) | Recruiting | Shanghai | Shanghai | 200032 | China | Details |
| Renji Hospital Shanghai Jiao Tong University School of Medicine ( Site 1402) | Recruiting | Shanghai | Shanghai | 200127 | China | Details |
| Fakultni nemocnice u sv. Anny v Brne ( Site 0253) | Recruiting | Brno | Jihomoravsky Kraj | 656 91 | Czechia | Details |
| Fakultni nemocnice Hradec Kralove-Klinika onkologie a radioterapie ( Site 0254) | Recruiting | Hradec Kralove | 500 05 | Czechia | Details | |
| Fakultni Nemocnice Olomouc ( Site 0251) | Recruiting | Olomouc | 779 00 | Czechia | Details | |
| Fakultni Thomayerova nemocnice ( Site 0252) | Recruiting | Praha 4 | 140 59 | Czechia | Details | |
| CHU La Timone ( Site 0456) | Recruiting | Marseille | Bouches-du-Rhone | 13005 | France | Details |
| CHU Jean Minjoz ( Site 0453) | Recruiting | Besancon | Doubs | 25000 | France | Details |
| CHU de Brest -Site Hopital Morvan ( Site 0461) | Recruiting | Brest | Finistere | 29200 | France | Details |
| Institut Universitaire du Cancer Toulouse - Oncopole ( Site 0455) | Recruiting | Toulouse | Haute-Garonne | 31059 | France | Details |
| CHU Limoges Hopital Dupuytren ( Site 0459) | Recruiting | Limoges | Haute-Vienne | 87042 | France | Details |
| Gustave Roussy ( Site 0467) | Recruiting | Villejuif | Ile-de-France | 94800 | France | Details |
| Centre Hospitalier Regional du Orleans ( Site 0463) | Recruiting | Orleans | Loiret | 45067 | France | Details |
| Polyclinique du Bois ( Site 0458) | Recruiting | Lille | Nord | 59000 | France | Details |
| Hopital Diaconesses Croix Saint Simon ( Site 0465) | Recruiting | Paris | 75020 | France | Details | |
| Universitaetsklinikum Freiburg ( Site 0512) | Recruiting | Freiburg | Baden-Wurttemberg | 79106 | Germany | Details |
| Universitaetsklinik fuer Urologie ( Site 0501) | Recruiting | Tuebingen | Baden-Wurttemberg | 72076 | Germany | Details |
| Caritas Krankenhaus St. Josef ( Site 0502) | Recruiting | Regensburg | Bayern | 93053 | Germany | Details |
| Kath. Krankenhaus Marienhospital. Universitaetsklinik ( Site 0511) | Recruiting | Herne | Nordrhein-Westfalen | 44625 | Germany | Details |
| Universitaetsklinikum Muenster ( Site 0516) | Recruiting | Muenster | Nordrhein-Westfalen | 48149 | Germany | Details |
| Krankenhaus Martha Maria Halle-Doelau ( Site 0507) | Recruiting | Halle | Sachsen-Anhalt | 06120 | Germany | Details |
| Universitaetsklinikum Carl Gustav Carus ( Site 0509) | Recruiting | Dresden | Sachsen | 01307 | Germany | Details |
| Vivantes Klinikum Am Urban ( Site 0519) | Recruiting | Berlin | 10967 | Germany | Details | |
| UNIVERSITY HOSPITAL OF PATRAS-DIVISION OF ONCOLOGY ( Site 0305) | Recruiting | Patras | Achaia | 26504 | Greece | Details |
| General Hospital of Athens "Alexandra" ( Site 0303) | Recruiting | Athens | Attiki | 115 28 | Greece | Details |
| Athens Medical Center ( Site 0304) | Recruiting | Athens | Attiki | 151 25 | Greece | Details |
| ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 0301) | Recruiting | Chaidari | Attiki | 124 62 | Greece | Details |
| University General Hospital of Larissa ( Site 0302) | Recruiting | Larissa | Thessalia | 411 10 | Greece | Details |
| Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ ( Site 1010) | Recruiting | Szeged | Csongrad | 6720 | Hungary | Details |
| Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház ( Site 1002) | Recruiting | Szolnok | Jasz-Nagykun-Szolnok | 5004 | Hungary | Details |
| Debreceni Egyetem Klinikai Kozpont ( Site 1006) | Recruiting | Debrecen | 4032 | Hungary | Details | |
| Rambam Health Care Campus-Oncology ( Site 0751) | Recruiting | Haifa | 3109601 | Israel | Details | |
| Hadassah Medical Center-Oncology ( Site 0757) | Recruiting | Jerusalem | 9112001 | Israel | Details | |
| Meir Medical Center-oncology ( Site 0754) | Recruiting | Kfar Saba | 4428164 | Israel | Details | |
| Rabin Medical Center-Oncology ( Site 0752) | Recruiting | Petah-Tikva | 4941492 | Israel | Details | |
| Sheba Medical Center-ONCOLOGY ( Site 0753) | Recruiting | Ramat Gan | 5262100 | Israel | Details | |
| Sourasky Medical Center-Oncology ( Site 0755) | Recruiting | Tel Aviv | 64239 | Israel | Details | |
| Yitzhak Shamir Medical Center-Oncology ( Site 0756) | Recruiting | Zerifin | 70300 | Israel | Details | |
| Presidio Ospedaliero Santa Maria delle Grazie ( Site 0599) | Recruiting | Pozzuoli | Napoli | 80078 | Italy | Details |
| AOU San Luigi Gonzaga di Orbassano ( Site 0595) | Recruiting | Orbassano | Torino | 10043 | Italy | Details |
| Istituto Oncologico Veneto IRCCS-Oncologia Medica 1 ( Site 0600) | Recruiting | Padova | Veneto | 35128 | Italy | Details |
| Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento ( Site 0598) | Recruiting | Verona | Veneto | 37126 | Italy | Details |
| Ospedali Riuniti Umberto I GM Lancis G Salesi ( Site 0593) | Recruiting | Ancona | 60126 | Italy | Details | |
| Ospedale Cannizzaro ( Site 0590) | Recruiting | Catania | 95126 | Italy | Details | |
| IRCCS Ospedale San Raffaele ( Site 0596) | Recruiting | Milano | 20132 | Italy | Details | |
| Nagoya University Hospital ( Site 1512) | Recruiting | Nagoya | Aichi | 466-8560 | Japan | Details |
| Hirosaki University Hospital ( Site 1501) | Recruiting | Hirosaki | Aomori | 036-8563 | Japan | Details |
| University of Tsukuba Hospital ( Site 1502) | Recruiting | Tsukuba | Ibaraki | 305-8576 | Japan | Details |
| Kanazawa University Hospital ( Site 1509) | Recruiting | Kanazawa | Ishikawa | 920-8641 | Japan | Details |
| Yokohama City University Medical Center ( Site 1508) | Completed | Yokohama | Kanagawa | 232-0024 | Japan | Details |
| Kanagawa Cancer Center ( Site 1507) | Recruiting | Yokohama | Kanagawa | 241-8515 | Japan | Details |
| Tohoku University Hospital ( Site 1503) | Recruiting | Sendai | Miyagi | 980-8574 | Japan | Details |
| Hamamatsu University Hospital ( Site 1511) | Recruiting | Hamamatsu | Shizuoka | 431-3192 | Japan | Details |
| Gifu University Hospital ( Site 1513) | Recruiting | Gifu | 501-1194 | Japan | Details | |
| Nagasaki University Hospital ( Site 1517) | Recruiting | Nagasaki | 852-8510 | Japan | Details | |
| Okayama University Hospital ( Site 1516) | Recruiting | Okayama | 7008558 | Japan | Details | |
| Osaka International Cancer Institute ( Site 1514) | Recruiting | Osaka | 5418567 | Japan | Details | |
| Osaka Metropolitan University Hospital ( Site 1515) | Recruiting | Osaka | 545-8586 | Japan | Details | |
| Tokyo Medical and Dental University Hospital ( Site 1505) | Recruiting | Tokyo | 113-8519 | Japan | Details | |
| Keio University Hospital ( Site 1504) | Recruiting | Tokyo | 160-8582 | Japan | Details | |
| Toyama University Hospital ( Site 1510) | Recruiting | Toyama | 930-0194 | Japan | Details | |
| Chonnam National University Hwasun Hospital ( Site 1353) | Recruiting | Jeollanam-do | Jeonranamdo | 58128 | Korea, Republic of | Details |
| Seoul National University Bundang Hospital ( Site 1355) | Recruiting | Gyeonggi-do | Kyonggi-do | 13620 | Korea, Republic of | Details |
| Asan Medical Center ( Site 1352) | Recruiting | Songpagu | Seoul | 05505 | Korea, Republic of | Details |
| Kyungpook National University Chilgok Hospital ( Site 1354) | Recruiting | Daegu | Taegu-Kwangyokshi | 41404 | Korea, Republic of | Details |
| Gachon University Gil Medical Center ( Site 1356) | Recruiting | Incheon | 21565 | Korea, Republic of | Details | |
| Korea University Anam Hospital ( Site 1357) | Recruiting | Seoul | 02841 | Korea, Republic of | Details | |
| Seoul National University Hospital ( Site 1351) | Recruiting | Seoul | 03080 | Korea, Republic of | Details | |
| University Malaya Medical Centre ( Site 0352) | Recruiting | Lembah Pantai | Kuala Lumpur | 59100 | Malaysia | Details |
| Hospital Pulau Pinang ( Site 0355) | Recruiting | George Town | Pulau Pinang | 10990 | Malaysia | Details |
| Sarawak General Hospital ( Site 0351) | Recruiting | Kuching | Sarawak | 93586 | Malaysia | Details |
| Sunway Medical Centre ( Site 0353) | Recruiting | Petaling Jaya | Selangor | 47500 | Malaysia | Details |
| THE MEDICAL CITY ILOILO-The Medical City Iloilo - Clinical and Translational Research Institute-Ilo | Recruiting | Iloilo City | Iloilo | 5000 | Philippines | Details |
| Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu ( Site 1058) | Recruiting | Wrocław | Dolnoslaskie | 50-556 | Poland | Details |
| Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1057) | Recruiting | Siedlce | Mazowieckie | 08-110 | Poland | Details |
| Narodowy Instytut Onkologii ( Site 1051) | Recruiting | Warszawa | Mazowieckie | 02-781 | Poland | Details |
| Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1053) | Recruiting | Przemysl | Podkarpackie | 37-700 | Poland | Details |
| Clinical Research Center Medic-R ( Site 1061) | Recruiting | Poznan | Wielkopolskie | 61-731 | Poland | Details |
| Szpital Wojewodzki im. Mikolaja Kopernika ( Site 1055) | Recruiting | Koszalin | Zachodniopomorskie | 75-581 | Poland | Details |
| Centro Hospitalar e Universitario de Coimbra ( Site 0406) | Recruiting | Coimbra | 3000-075 | Portugal | Details | |
| Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE ( Site 0409) | Recruiting | Lisboa | 1099-023 | Portugal | Details | |
| CHLO, EPE - Hospital de Sao Francisco Xavier ( Site 0401) | Recruiting | Lisboa | 1449-005 | Portugal | Details | |
| Hospital Geral de Santo Antonio ( Site 0408) | Recruiting | Porto | 4099-001 | Portugal | Details | |
| Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1102) | Recruiting | Cluj Napoca | Cluj | 400015 | Romania | Details |
| Cardiomed SRL Cluj-Napoca ( Site 1101) | Recruiting | Cluj-Napoca | Cluj | 400015 | Romania | Details |
| Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1103) | Recruiting | Cluj-Napoca | Cluj | 400015 | Romania | Details |
| SC Radiotherapy Center Cluj SRL ( Site 1108) | Recruiting | Comuna Floresti | Cluj | 407280 | Romania | Details |
| S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 1107) | Recruiting | Craiova | Dolj | 200542 | Romania | Details |
| Policlinica Oncomed SRL ( Site 1106) | Recruiting | Timisoara | Timis | 300239 | Romania | Details |
| SC Focus Lab Plus SRL ( Site 1104) | Recruiting | Bucuresti | 022548 | Romania | Details | |
| Altay Regional Oncology Dispensary ( Site 0851) | Suspended | Barnaul | Altayskiy Kray | 656045 | Russian Federation | Details |
| National Medical Research Radiology Centre ( Site 0869) | Suspended | Obninsk | Kaluzskaja Oblast | 249036 | Russian Federation | Details |
| National Medical Research Centre of Oncology named after N.N. Blokhin ( Site 0865) | Suspended | Moscow | Moskva | 115230 | Russian Federation | Details |
| First Moscow State Medical University n.a. I.M.Sechenov ( Site 0871) | Suspended | Moscow | Moskva | 119991 | Russian Federation | Details |
| Volga District Medical Center ( Site 0876) | Suspended | Nizhny Novgorod | Nizhegorodskaya Oblast | 603074 | Russian Federation | Details |
| St.Petersburg Clinical Hospital RAS ( Site 0864) | Suspended | Saint Petersburg | Sankt-Peterburg | 194017 | Russian Federation | Details |
| St.Petersburg State Medical Univ. n.a. acad. I.P.Pavlov ( Site 0856) | Suspended | Saint Petersburg | Sankt-Peterburg | 197101 | Russian Federation | Details |
| Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 0852) | Suspended | Saint Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details |
| Sverdlovsk Regional Oncology Hospital ( Site 0867) | Suspended | Ekaterinburg | Sverdlovskaya Oblast | 620036 | Russian Federation | Details |
| Sverdlovsky Regional Clinical hospital #1 ( Site 0868) | Suspended | Ekaterinburg | Sverdlovskaya Oblast | 620102 | Russian Federation | Details |
| Volgograd Regional Uronephrological Center ( Site 0870) | Suspended | Volzhsky | Volgogradskaya Oblast | 404120 | Russian Federation | Details |
| Tan Tock Seng Hospital ( Site 0704) | Recruiting | Singapore | Central Singapore | 398442 | Singapore | Details |
| Wits Clinical Research ( Site 0603) | Recruiting | Johannesburg | Gauteng | 2193 | South Africa | Details |
| Steve Biko Academic Hospital ( Site 0601) | Recruiting | Pretoria | Gauteng | 0002 | South Africa | Details |
| Groote Schuur Hospital ( Site 0602) | Recruiting | Cape Town | Western Cape | 7925 | South Africa | Details |
| Hospital Universitario Central de Asturias ( Site 0654) | Recruiting | Oviedo | Asturias | 33011 | Spain | Details |
| Hospital Germans Trias i Pujol. ICO de Badalona ( Site 0658) | Recruiting | Badalona | Barcelona | 08916 | Spain | Details |
| Xarxa Assistencial Universitaria Manresa ( Site 0655) | Recruiting | Manresa | Barcelona | 08243 | Spain | Details |
| Hospital Universitari de Girona Doctor Josep Trueta ( Site 0653) | Recruiting | Girona | Gerona | 17007 | Spain | Details |
| CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 0660) | Recruiting | Santiago de Compostela | La Coruna | 15706 | Spain | Details |
| Hospital Universitario Insular de Gran Canaria ( Site 0657) | Recruiting | Las Palmas de Gran Canaria | Las Palmas | 35001 | Spain | Details |
| Fundación Instituto Valenciano de Oncología-Oncologico ( Site 0662) | Recruiting | Valencia | Valenciana, Comunitat | 46009 | Spain | Details |
| Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0661) | Recruiting | Barcelona | 08035 | Spain | Details | |
| Hospital Clinico Universitario San Carlos de Madrid ( Site 0651) | Recruiting | Madrid | 28040 | Spain | Details | |
| Hospital Virgen del Rocio ( Site 0659) | Recruiting | Sevilla | 41013 | Spain | Details | |
| China Medical University Hospital ( Site 1202) | Recruiting | Taichung | 404332 | Taiwan | Details | |
| Taipei Veterans General Hospital ( Site 1201) | Recruiting | Taipei | 11217 | Taiwan | Details | |
| I.I. Mechnykov Dnipropetrovsk Regional Clinical Hospital ( Site 0959) | Suspended | Dnipro | Dnipropetrovska Oblast | 49005 | Ukraine | Details |
| MI Clinical oncology dispensary of Dnipropetrovsk regional council ( Site 0954) | Suspended | Dnipro | Dnipropetrovska Oblast | 49055 | Ukraine | Details |
| Regional Clinical Center of Urology and Nephrology n.a. V.I. Shapoval ( Site 0952) | Suspended | Kharkiv | Kharkivska Oblast | 61037 | Ukraine | Details |
| MNPE Regional Center of Oncology ( Site 0955) | Suspended | Kharkiv | Kharkivska Oblast | 61070 | Ukraine | Details |
| Municipal Non-profit Enterprise of Kharkiv Regional Council RCSDRPP ( Site 0965) | Suspended | Kharkiv | Kharkivska Oblast | 61166 | Ukraine | Details |
| Lviv Oncology Regional Treatment and Diagnostic Center ( Site 0960) | Suspended | Lviv | Lvivska Oblast | 79031 | Ukraine | Details |
| Zhytomyr Regional Oncology Center ( Site 0961) | Suspended | Zhytomyr | Zhytomyrska Oblast | 10002 | Ukraine | Details |