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| NCT ID | NCT04740918 |
| Title | A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC) (KATE3) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Emad Ibrahim, Md, Inc | Redlands | California | 92373 | United States | Details | |
| Lake Macquarie Private Hospital | Gateshead | New South Wales | 2290 | Australia | Details | |
| Royal North Shore Hospital; Oncology | St. Leonards | New South Wales | 2065 | Australia | Details | |
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Peter MacCallum Cancer Center | North Melbourne | Victoria | 3051 | Australia | Details | |
| Sunshine Hospital | St Albans | Victoria | 3021 | Australia | Details | |
| Hospital Sao Rafael - HSR | Salvador | BA | 41253-190 | Brazil | Details | |
| Hospital Araujo Jorge; Departamento de Ginecologia E Mama | Goiania | GO | 74605-070 | Brazil | Details | |
| Hospital do Cancer de Pernambuco - HCP | Recife | PE | 50040-000 | Brazil | Details | |
| Hospital de Caridade de Ijui; Oncologia | Ijui | RS | 98700-000 | Brazil | Details | |
| Hospital Nossa Senhora da Conceicao | Porto Alegre | RS | 91350-200 | Brazil | Details | |
| Hospital de Base de Sao Jose do Rio Preto | Sao Jose do Rio Preto | SP | 15090-000 | Brazil | Details | |
| Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda | Sao Paulo | SP | 01317-001 | Brazil | Details | |
| Núcleo de Pesquisa São Camilo; ONCOLOGIA CLINICA / QUIMIOTERAPIA | Sao Paulo | SP | 04014-002 | Brazil | Details | |
| Royal Victoria Hospital | Barrie | Ontario | L4M 6M2 | Canada | Details | |
| Lakeridge Health Oshawa; Oncology | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| The Ottawa Hospital Cancer Centre; Oncology | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Research Institute | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Centre Hospitalier de l?Université de Montréal (CHUM) | Montreal | Quebec | H2X 0C2 | Canada | Details | |
| McGill University Health Center | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Jewish General Hospital; Research Unit | Montréal | Quebec | H3T 1E2 | Canada | Details | |
| CHUS (Centre Hospitalier Universitaire de Sherbrooke) | Sherbrooke | Quebec | J1H 5N4 | Canada | Details | |
| Peking University People's Hospital | Beijing | 100044 | China | Details | ||
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| The First Hospital of Jilin University | Changchun City | 130021 | China | Details | ||
| Hunan Cancer Hospital | Changsha CITY | 410013 | China | Details | ||
| Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Breast Tumor Center | Guangzhou City | 510120 | China | Details | ||
| The Second Affiliated Hospital, Zhejiang University | Hangzhou | 310009 | China | Details | ||
| Zhejiang Provincial People's Hospital; Oncology& Breast | Hangzhou | 310014 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Yunnan Cancer Hospital; Breast Surgery | Kunming City | 650100 | China | Details | ||
| Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University) | Nanjing City | 210029 | China | Details | ||
| Peking University Shenzhen Hospital | Shenzhen | 518036 | China | Details | ||
| Tianjin Medical University Cancer Institute & Hospital | Tianjing | 300060 | China | Details | ||
| Union Hospital Tongji Medical College Huazhong University of Science and Technology | Wuhan City | 430023 | China | Details | ||
| Shanxi Provincial People's Hospital | Xian | 710068 | China | Details | ||
| Zhejiang Cancer Hospital | Zhejiang | 310022 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| Clinica Vida | Medellin | Colombia | Details | |||
| Oncomedica S.A. | Monteria | 230002 | Colombia | Details | ||
| Oncólogos de Occidente | Pereira | 600004 | Colombia | Details | ||
| Clinical Hospital Centre Split | Split | 21000 | Croatia | Details | ||
| Clinical Hospital Center Sestre Milosrdnice; Clinic for tumors | Zagreb | 10000 | Croatia | Details | ||
| Clinical Hospital Centre Zagreb | Zagreb | 10000 | Croatia | Details | ||
| Helsinki University Central Hospital; Dept of Oncology | Helsinki | 00250 | Finland | Details | ||
| Oulu University Hospital; Oncology | Oulu | 90029 | Finland | Details | ||
| Tampere University Hospital; Dept of Oncology | Tampere | 33520 | Finland | Details | ||
| CHU Amiens - Hopital Sud | Amiens | 80054 | France | Details | ||
| Polyclinique Bordeaux Nord Aquitaine | Bordeaux | 33300 | France | Details | ||
| Chu Grenoble - Hopital Albert Michallon; Departement de Cancero-Hematologie | Grenoble | 38043 | France | Details | ||
| Centre Oscar Lambret; Senologie | Lille | 59020 | France | Details | ||
| Centre Antoine Lacassagne, Centre de Lutte Contre le Cancer (CLCC) de Nice | Nice | 06189 | France | Details | ||
| Groupe Hospitalier Diaconesses Croix Saint-Simon - Site Reuilly) | Paris | 75020 | France | Details | ||
| Chu La Miletrie; Oncologie Medicale | Poitiers | 86021 | France | Details | ||
| Institut Curie - Hopital Rene Huguenin | Saint-Cloud | 92211 | France | Details | ||
| Institut Universitaire du Cancer de Toulouse-Oncopole | Toulouse | 31059 | France | Details | ||
| Anticancer Hospital Ag Savas; 1St Dept of Internal Medicine | Athens | 115 22 | Greece | Details | ||
| Alexandras General Hospital of Athens; Oncology Department | Athens | 115 28 | Greece | Details | ||
| University General Hospital of Heraklion;Internal Medicine-Oncology Clinic | Heraklion, Crete | 711 10 | Greece | Details | ||
| Euromedical General Clinic of Thessaloniki; Oncology Department | Thessaloniki | 546 45 | Greece | Details | ||
| Szent Margit Hospital | Budapest | 1032 | Hungary | Details | ||
| Orszagos Onkologiai Intezet; B Belgyogyaszati Osztaly | Budapest | 1122 | Hungary | Details | ||
| Debreceni Egyetem Klinikai Kozpont ; Department of Oncology | Debrecen | 4032 | Hungary | Details | ||
| Borsod-Abauj-Zemplen Megyei Korhaz Es Egyetemi Oktato Korhaz; Onkologiai Osztaly | Miskolc | 3501 | Hungary | Details | ||
| Azienda Ospedaliera di Rilievo Nazionale e di Alta Specialita San Giuseppe Moscati | Avellino | Campania | 83100 | Italy | Details | |
| Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica | Napoli | Campania | 80131 | Italy | Details | |
| Università degli Studi Federico II; Clinica di Oncologia Medica | Napoli | Campania | 80131 | Italy | Details | |
| Azienda Ospedaliera S. Orsola-Malpighi | Bologna | Emilia-Romagna | 40138 | Italy | Details | |
| Azienda Unità Sanitaria Locale di Reggio Emilia/IRCCS | Reggio Emilia | Emilia-Romagna | 42123 | Italy | Details | |
| Ospedale Policlinico San Martino; Ist. di Ricovero e Cura a Carattere Scientifico per l'Oncologia | Genova | Liguria | 16132 | Italy | Details | |
| Asst Papa Giovanni XXIII | Bergamo | Lombardia | 24100 | Italy | Details | |
| Ospedale San Raffaele; Medical Oncology | Milano | Lombardia | 20132 | Italy | Details | |
| Istituto Europeo Di Oncologia | Milano | Lombardia | 20141 | Italy | Details | |
| Istituto Clinico Humanitas;U.O. Oncologia Medica Ed Ematologia | Rozzano | Lombardia | 20089 | Italy | Details | |
| Azienda Ospedaliero Universitaria Pisana | Pisa | Toscana | 56126 | Italy | Details | |
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Korea University Guro Hospital | Seoul | 08308 | Korea, Republic of | Details | ||
| Haukeland universitetssjukehus, Avd. for kreftbehandling og medisinsk fysikk | Bergen | 5021 | Norway | Details | ||
| Sykehuset Østfold Kalnes; Onkologisk seksjon | Grålum | 1714 | Norway | Details | ||
| Oslo Universitetssykehus HF; Ullevål sykehus | Oslo | 0450 | Norway | Details | ||
| Stavanger Universitetssykehus, Helse Stavanger HF | Stavanger | 4011 | Norway | Details | ||
| Cebu Doctors' University Hospital; Research Office | Cebu City | 6000 | Philippines | Details | ||
| St. Luke's Medical Center; Human Cancer Biobank Research Center | Quezon City | 1102 | Philippines | Details | ||
| Cardinal Santos Medical Center; Lower Ground Floor Research Room, Cancer Center | San Juan | 1502 | Philippines | Details | ||
| Copernicus Podmiot Medyczny Sp. z o.o. Wojewodzkie Centrum Onkologii | Gdansk | 80-219 | Poland | Details | ||
| Przychodnia Lekarska KOMED, Roman Karaszewski | Konin | 62-500 | Poland | Details | ||
| Szpital Wojewódzki im. Miko?aja Kopernika; Oddzia? Dzienny Chemioterapii | Koszalin | 75-581 | Poland | Details | ||
| Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii | Kraków | 30-688 | Poland | Details | ||
| Centrum Terapii Wspolczesnej J.M.Jasnorzewska Spolka Komandytowo-Akcyjna | Lodz | 90-242 | Poland | Details | ||
| Opolskie Centrum Onkologii;Oddzial Onkologii Klinicznej | Opole | 45-060 | Poland | Details | ||
| Szpital Kliniczny; Przemienienia Panskiego;Uniwersytetu Medyczny im.; Karola Marcinkowskiego w Pozna | Poznan | 60-569 | Poland | Details | ||
| Centrum Onkologii ? Instytut im. Marii Sk?odowskiej-Curie Klinika Nowotworów Piersi i Chirurgii | Warszawa | 02-781 | Poland | Details | ||
| Mazowiecki Szpital Onkologiczny | Wieliszew | 05-135 | Poland | Details | ||
| IPO de Lisboa; Servico de Oncologia Medica | Lisboa | 1099-023 | Portugal | Details | ||
| Hospital de Santa Maria; Servico de Oncologia Medica | Lisboa | 1649-035 | Portugal | Details | ||
| Centro Hospitalar do Porto ? Hospital de Santo António; Oncologia | Porto | 4099-001 | Portugal | Details | ||
| IPO do Porto; Servico de Oncologia Medica | Porto | 4200-072 | Portugal | Details | ||
| FSBSI ?N. N. Blokhin Russian Cancer Research Center? | Moscow | 115478 | Russian Federation | Details | ||
| City Clinical Oncology Dispensary, SPb SBIH CCOD | Saint-Petersburg | 198255 | Russian Federation | Details | ||
| Samara Regional Oncology Dispensary | Samara | 443031 | Russian Federation | Details | ||
| State Healthcare Institution ?Regional Clinical Oncology Dispensary? | Saratov | 410053 | Russian Federation | Details | ||
| St. Petersburg Clinical Scientific Center of special services medical assis (oncology) | ST Petersburg | 197758 | Russian Federation | Details | ||
| SBIH Republican Clinical Oncological Dispensary of the MoH of Republic Bashkortostan | Ufa | 450054 | Russian Federation | Details | ||
| Institute of Oncology Ljubljana | Ljubljana | 1000 | Slovenia | Details | ||
| Hospital Provincial de Castellon; Servicio de Oncologia | Castellon de La Plana | Castellon | 12002 | Spain | Details | |
| Hospital Universitario Quiron Madrid; Servicio de Oncologia | Pozuelo de Alarcón | Madrid | 28223 | Spain | Details | |
| Complexo Hospitalario de Vigo. Hospital Álvaro Cunqueiro; Servicio de Oncología | Vigo | Pontevedra | 36312 | Spain | Details | |
| Hospital Universitari Vall d'Hebron; Oncology | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario La Paz; Servicio de Oncologia | Madrid | 28046 | Spain | Details | ||
| Hospital Regional Universitario Carlos Haya; Servicio de Oncologia | Malaga | 29011 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Adana Baskent University Medical Faculty; Oncology | Adana | 01220 | Turkey | Details | ||
| Sakarya Universitesi Egitim ve Arastirma Hastanesi | Adapazari/Sakarya | 54100 | Turkey | Details | ||
| Memorial Ankara Hastanesi | Ankara | 06520 | Turkey | Details | ||
| Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji | Bakirkoy / Istanbul | 34147 | Turkey | Details | ||
| Acibadem University School of Medicine Altunizade Hospital Oncology Service | Istanbul | 34742 | Turkey | Details | ||
| Katip Celebi University Ataturk Training and Research Hospital; Oncology | Izmir | 35360 | Turkey | Details | ||
| Kayseri Acibadem Hospital | Kayseri | 38000 | Turkey | Details | ||
| Inonu University Faculty of Medicine Turgut Ozal Medical Center; Onkoloji, Elazig Yolu, | Malatya | 44280 | Turkey | Details | ||
| Hacettepe Uni Medical Faculty Hospital; Oncology Dept | Sihhiye/Ankara | 06230 | Turkey | Details | ||
| Leicester Royal Infirmary NHS Trust | Leicester | LE1 5WW | United Kingdom | Details | ||
| UCL Hospital NHS Trust | London | NW1 2PG | United Kingdom | Details | ||
| Guys and St Thomas NHS Foundation Trust, Guys Hospital | London | SE1 9RT | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| Milton Keynes University Hospital | Milton Keynes | MK6 5LD | United Kingdom | Details | ||
| Nottingham University Hospitals City Campus; Nottingham Cancer Clinical Trials Team | Nottingham | NG5 1PB | United Kingdom | Details | ||
| Peterborough City Hospital | Peterborough | PE3 9GZ | United Kingdom | Details |