Clinical Trial Detail


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NCT ID NCT04778397
Title Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated (ENHANCE-2)
Acronym ENHANCE-2
Recruitment Terminated
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Gilead Sciences
Age Groups: adult | senior
Covered Countries USA | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT | AUS

Facility Status City State Zip Country Details
University of Alabama at Birmingham Birmingham Alabama 35294 United States Details
City of Hope (City of Hope National Medical Center, City of Hope Medical Center) Duarte California 91010 United States Details
USC/ Norris Comprehensive Cancer Center Los Angeles California 90033 United States Details
Ronald Reagan UCLA Medical Center Los Angeles California 90095 United States Details
UC Irvine Health Orange California 92868 United States Details
Colorado Blood Cancer Institute Denver Colorado 80218 United States Details
Mayo Clinic Florida Jacksonville Florida 32224 United States Details
Miami Cancer Institute Miami Florida 33176 United States Details
AdventHealth Orlando Orlando Florida 32804 United States Details
Memorial Cancer Institute Pembroke Pines Florida 33028 United States Details
Moffitt Cancer Center Tampa Florida 33612 United States Details
Winship Cancer Institute Atlanta Georgia 30322 United States Details
Northwestern Memorial Hospital/Main Lab Chicago Illinois 60611 United States Details
The University of Chicago Medical Centre Chicago Illinois 60637 United States Details
University of Kansas Hospital Fairway Kansas 66205 United States Details
University of Kentucky Medical Center Lexington Kentucky 40536 United States Details
Tulane Medical center New Orleans Louisiana 70112 United States Details
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland 21231 United States Details
Massachusetts General Hospital Boston Massachusetts 02114 United States Details
Dana-Farber Cancer Institute Boston Massachusetts 02215 United States Details
Mayo Clinic Cancer Center Outpatient Pharmacy Rochester Minnesota 55905 United States Details
MidAmerica Division, Inc., c/o Research Medical Center Kansas City Missouri 64132 United States Details
SSM Health Saint Louis University Hospital Saint Louis Missouri 63110 United States Details
Roswell Park Cancer Institute Buffalo New York 14263 United States Details
Columbia University Medical Center - Herbert Irving Pavilion New York New York 10032 United States Details
UNC Hospitals, The University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 United States Details
Duke Blood Cancer Center Durham North Carolina 27705 United States Details
The Ohio State University Wexner Medical Center/ James Cancer Hospital Columbus Ohio 43210 United States Details
University of Oklahoma Health Sciences Center - OU Health Stephenson Cancer Center Oklahoma City Oklahoma 73104 United States Details
Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization Philadelphia Pennsylvania 19107 United States Details
St. Francis Cancer Center Greenville South Carolina 29607 United States Details
Prisma Health Cancer Institute Greenville South Carolina 29615 United States Details
Baylor College of Medicine Medical Center Houston Texas 77030 United States Details
The University of Texas MD Anderson Cancer Center Houston Texas 77030 United States Details
Huntsman Cancer Institute ,The University of Utah Salt Lake City Utah 84112 United States Details
Froedtert Hospital / Medical College of Wisconsin Milwaukee Wisconsin 53226 United States Details
Canberra Hospital Garran Australian Capital Territory 2605 Australia Details
Calvary Master Newcastle Waratah New South Wales 2298 Australia Details
Westmead Hospital / Department of Haematology and Bone Marrow Transplantation Westmead New South Wales 2145 Australia Details
Princess Alexandra Hospital Woolloongabba Queensland 4102 Australia Details
Royal Adelaide Hospital Adelaide South Australia 5000 Australia Details
Andrew Love Cancer Centre, University Hospital Geelong Geelong Victoria 3220 Australia Details
The Alfred Melbourne Victoria 3004 Australia Details
St Vincents Hospital Melbourne Melbourne Victoria 3122 Australia Details
Fiona Stanley Hospital Murdoch Western Australia 6150 Australia Details
Royal Perth Hospital Perth Western Australia 6000 Australia Details
Univ. -Klinik für Hämatologie und Internistische Onkologie, Kepler Universitätskilkun GmbHMed Linz 4021 Austria Details
Uniklinikum Salzburg, Universitatsklinik f. Innere Medizin III der PMU Salzburg 5020 Austria Details
Algemeen Ziekenhuis Sint-Jan Brugge-Oostende AV Brugge 8000 Belgium Details
Universitair Ziekenhuis Brussel Brussels Belgium Details
Grand Hôpital De Charleroi - Notre Dame Charleroi 6000 Belgium Details
Universitaire Ziekenhuis Antwerpen Edegem Belgium Details
Universitair Ziekenhuis Gent Gent 9000 Belgium Details
AZ Delta vzw Roeselare 8800 Belgium Details
Tom Baker Cancer Center Calgary T2N 4N2 Canada Details
Queen Elizabeth II Health Sciences Centre Halifax B3H 1V7 Canada Details
CIUSSS de L'Est-de-L'Ile-de- Montreal - Hopital Maisonneuve-Rosemont Montreal H1T 2M4 Canada Details
McGill University Health Centre Montreal H4A 3J1 Canada Details
Sunnybrook Research Institute Toronto M4N 3M5 Canada Details
Princess Margaret Cancer Centre Toronto M5G 2M9 Canada Details
Aalborg University Hospital Aalborg 9000 Denmark Details
Odense University Hospital Odense C 5000 Denmark Details
CHU d'Angers Angers cedex 49933 France Details
CHU de Caen Caen cedex 14033 France Details
CHRU Lille - Hospital Claude Huriez Lille 59037 France Details
CHU Limoges Limoges 87042 France Details
Central Hospital Lyon Sud Lyon 69495 France Details
Institut Paoli Calmettes Marseille 13009 France Details
CHU de Nantes, Hotel Dieu Nantes 44093 France Details
CHU Nice - Hopital Archet 1 Nice 6200 France Details
Gustave Roussy Paris 94805 France Details
Hopital Haut-Leveque Pessac 33604 France Details
IUCT Oncopole Toulouse 31059 France Details
Hopitaux de Brabois Vandoeuvre-lès-Nancy France Details
Uniklinik RWTH Aachen, Medizinische Klunuk IV - Klinik fur Hamatologie, Onkologie, Hamastaseologie und Srammzelltransplantation Aachen 52074 Germany Details
Dept. of Hematology, Oncology and Tumor Immunology, Charite- University Medicine Berlin, Campus Virchow Klinikum Berlin 13353 Germany Details
Department of Hematology and Oncology, Braunschweig Community Hospital Braunschweig 38114 Germany Details
Universitatsklinikum Carl Gustav Carus Dresden an der Technische Universitat Dresden, Medizinische Klinik und Poliklinik 1, Bereich Hamatologie Dresden 01307 Germany Details
Universitätsklinikum Düsseldorf -Klinik für Hämatologie, Onkologie und Klinische Immunologie Dusseldorf 40225 Germany Details
Dept. of Medicine II, University Hospital Hamburg-Eppendorf Hamburg 20246 Germany Details
Universitatsklinikum Heidelberg, Innere Medizin V, Hamatologie, Onkologie und Rheumatologie Heidelberg 69120 Germany Details
Universitatsklinikum Schleswig-Holstein Kiel 24105 Germany Details
Universitatsklinikum Koln Köln 50937 Germany Details
Klinikum Ludwigshafen Medizinische Klinik A Ludwigshafen 67063 Germany Details
Klinikum rechts der Isar der Technischen Universitat Munchen, Klinik und Poliklinik fur Innere Medizin III Muenchen 81675 Germany Details
LMU - Klinikum der Universitat Munchen, Medizinische Klinik und Poliklinik III, Campus Grosshadern München 81377 Germany Details
Universitatsklinikum Ulm, Zentrum fur Innere Medizin, Innere Medizin III Ulm 89081 Germany Details
Prince of Wales Hospital, The Chinese University of Hong Kong Hong Kong Hong Kong Details
Queen Mary Hospital Hong Kong Hong Kong Details
Azienda Ospedaliero Universitaria delle Marche Ancona I-60126 Italy Details
AOU Consorziale Policlinico Bari Bari 70124 Italy Details
Azienda Ospedaliero-Universitaria di Bologna Policlinico Sant'Orsola-Malphigi U.O Ematologia Bologna 40138 Italy Details
Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRS - Oncologia Medica Meldola 40174 Italy Details
Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli U.O.S.C. di Ematologia con Trapianto di Midollo Osseo Napoli 80131 Italy Details
SC Ematologia, Azienda Ospedaliera di Perugia - Santa Maria della Misericordia Perugia 06129 Italy Details
AORM - AO Riuniti Marche Norde - Pesaro Presidio "San Salvatore" - Muraglia Pesaro 61122 Italy Details
Fondazione PTV Policinico Tor Vergata Roma 00133 Italy Details
SCDU Ematologia e Terrapie cellulari AO O Ordine Mauriziano Torino Torino 10122 Italy Details
ASST Sette Laghi - Ospedale di Circolo e Fondazione Macchi Varese 21100 Italy Details
Hyogo Prefectural Amagasaki General Medical Center Amagasaki 660-8550 Japan Details
Chiba Aoba Municipal Hospital Chiba 260-0852 Japan Details
University of Yamanashi Hospital Chuo-City 409-3898 Japan Details
Kyushu University Hospital Fukuoka 812-8582 Japan Details
Fukushima Medical University Hospital Fukushima-Shi 960-1295 Japan Details
Aiiku Hospital Hokkaido 064-0804 Japan Details
Tokai University School of Medicine Isehara 259-1193 Japan Details
Kanazawa University Hospital Kanazawa 920-8641 Japan Details
National Cancer Center Hospital East Kashiwa 277-8577 Japan Details
Hospital of the University of Occupational and Environmental Health, Japan Kitakyushu-shi 807-8555 Japan Details
Kobe City Medical Center General Hospital Kobe-city 650-0047 Japan Details
Gunmaken Saiseikai Maebashi Hospital Maebashi 371-0821 Japan Details
Ehime Prefectural Center Hospital Matsuyama 790-0024 Japan Details
Nagasaki University Hospital Nagasaki 852-8501 Japan Details
Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital Nagoya-Shi 466-8650 Japan Details
Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital Nagoya 453-8511 Japan Details
Okayama University Hospital Okayama-Shi 700-8558 Japan Details
Osaka Metropolitan University Hospital Osaka-Shi 545-8586 Japan Details
Kindai University Hospital Osakasayama 589-8511 Japan Details
National University Corporation Tohoku University Tohoku University Hospital Sendai 980-8574 Japan Details
NTT Medical Center Tokyo Shinagawa-Ku 141-8625 Japan Details
Yamagata University Hospital Yamagata 990-9585 Japan Details
University of Fukui Hospital Yoshida-gun 910-1193 Japan Details
Hospital General Universitario de Alicante Alicante 3010 Spain Details
Hospital del la Santa Creu i Sant Pau Barcelona 08025 Spain Details
Hospital Universitari Vall d'Hebron Barcelona 08035 Spain Details
Hospital Clinic de Barcelona Barcelona 08036 Spain Details
Institut Catala d'Oncologia Barcelona 08907 Spain Details
Complejo Asistencial Universitario de Burgos/H.U. de Burgos Burgos 09006 Spain Details
Hospital Universitario Reina Sofia Cordoba 14004 Spain Details
Complejo Hospitalario San Pedro de Alcantara Cáceres 10001 Spain Details
Hospital Universitario de Gran Canaria Doctor Negrin Las Palmas de Gran Canaria 35010 Spain Details
Hospital Universitario de La Princesa Madrid 28006 Spain Details
Hospital General Universitario Gregorio Maranon Madrid 28007 Spain Details
MD Anderson Cancer Center Madrid Madrid 28033 Spain Details
Hospital Regional Universitario de Malaga Malaga 29010 Spain Details
Hospital Universitario Central de Asturias Oviedo 33011 Spain Details
Clinica Universidad de Navarra - Pamplona (Main Site) Pamplona 31008 Spain Details
Complejo Asistencial Universitario de Salamanca - Hsopital Clinico Salamanca 37007 Spain Details
Hospital U. Marques de Valdecilla Santander 39008 Spain Details
Hospital Clinico Universitario de Valencia Valencia 46010 Spain Details
Hospital Universitari I Politècnic La Fe Valencia 46026 Spain Details
Universitetssjukhus, Hematologimottagnungen Lund 221 85 Sweden Details
Universitatsspital Basel - Klinik fur Hamatrologie, Bereich Innere Medizin Basel 4031 Switzerland Details
Inselspital, Universitatsspital Bern - Universitatsklinik fur Medizinisch Onkologie Berne CH 3010 Switzerland Details
University Hospitals Birmingham NHS Foundation Trust Birmingham B15 2GW United Kingdom Details
United Lincolnshire Hospitals NHS Trust, Pilgrim Hospital, Sibsey Road Boston PE21 9QS United Kingdom Details
Cambridge University Hospital NHS Foundation Trust Cambridge CB2 0QQ United Kingdom Details
Cardiff and Vale University Health Board Cardiff Wales CF14 4XW United Kingdom Details
Barts Health NHS Trust City of London EC1A 7BE United Kingdom Details
NHS Tayside Dundee DD1 9SY United Kingdom Details
Beatson West of Scotland Cancer Centre Glasgow G12 0YN United Kingdom Details
University College London Hospitals NHS Foundation Trust London NW1 2PG United Kingdom Details
King's College NHS Foundation Trust London SE5 9RS United Kingdom Details
Oxford University Hospital NHS Foundation Trust Oxford OX3 7LE United Kingdom Details
The Royal Marsden NHS Foundation Trust Sutton SM2 5PT United Kingdom Details
The Christie NHS Foundation Trust Withington M20 4BX United Kingdom Details
*Shaded cells indicate that there was no data available from for the field