Clinical Trial Detail


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NCT ID NCT04778397
Title Study to Evaluate the Safety and Efficacy of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Previously Untreated Adults With TP53 Mutant Acute Myeloid Leukemia (ENHANCE-2)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Gilead Sciences

acute myeloid leukemia


Cytarabine + Idarubicin

Azacitidine + Venetoclax

Azacitidine + Hu5F9-G4

Cytarabine + Daunorubicin

Age Groups: adult | senior
Covered Countries USA | FRA

Facility Status City State Zip Country Details
City of Hope (City of Hope National Medical Center, City of Hope Medical Center) Recruiting Duarte California 91010 United States Details
USC/ Norris Comprehensive Cancer Center Recruiting Los Angeles California 90033 United States Details
UC Irvine Health Recruiting Orange California 92868 United States Details
Colorado Blood Cancer Institute Recruiting Denver Colorado 80218 United States Details
The University of Chicago Medical Centre Recruiting Chicago Illinois 60637 United States Details
Tulane Medical center Recruiting New Orleans Louisiana 70112 United States Details
MidAmerica Division, Inc., c/o Research Medical Center Recruiting Kansas City Missouri 64132 United States Details
Washington University School of Medicine - Siteman Cancer Center Withdrawn Saint Louis Missouri 63110 United States Details
UNC Hospitals, The University of North Carolina at Chapel Hill Recruiting Chapel Hill North Carolina 27599 United States Details
The Ohio State University Wexner Medical Center/ James Cancer Hospital Recruiting Columbus Ohio 43210 United States Details
University of Oklahoma Health Sciences Center - OU Health Stephenson Cancer Center Recruiting Oklahoma City Oklahoma 73104 United States Details
Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization Recruiting Philadelphia Pennsylvania 19107 United States Details
St. Francis Cancer Center Recruiting Greenville South Carolina 29607 United States Details
Prisma Health Cancer Institute Recruiting Greenville South Carolina 29615 United States Details
The University of Texas MD Anderson Cancer Center Recruiting Houston Texas 77030 United States Details
Princess Alexandra Hospital Recruiting Woolloongabba Queensland 4102 Australia Details
Royal Adelaide Hospital Recruiting Adelaide South Australia 5000 Australia Details
The Alfred Recruiting Melbourne Victoria 3004 Australia Details
Fiona Stanley Hospital Recruiting Murdoch Western Australia 6150 Australia Details
Royal Perth Hospital Recruiting Perth Western Australia 6000 Australia Details
CHU d'Angers Recruiting Angers cedex 49933 France Details
CHU de Caen Recruiting Caen cedex 14033 France Details
CHU de Nantes, Hotel Dieu Recruiting Nantes 44093 France Details
IUCT Oncopole Recruiting Toulouse 31059 France Details
Prince of Wales Hospital, The Chinese University of Hong Kong Recruiting Hong Kong Hong Kong Details
Queen Mary Hospital Recruiting Hong Kong Hong Kong Details
Oxford University Hospital NHS Foundation Trust Recruiting Oxford OX3 7LE United Kingdom Details
*Shaded cells indicate that there was no data available from for the field