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| NCT ID | NCT04778397 |
| Title | Study to Evaluate the Safety and Efficacy of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Previously Untreated Adults With TP53 Mutant Acute Myeloid Leukemia (ENHANCE-2) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Gilead Sciences |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | FRA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Recruiting | Duarte | California | 91010 | United States | Details |
| USC/ Norris Comprehensive Cancer Center | Recruiting | Los Angeles | California | 90033 | United States | Details |
| UC Irvine Health | Recruiting | Orange | California | 92868 | United States | Details |
| Colorado Blood Cancer Institute | Recruiting | Denver | Colorado | 80218 | United States | Details |
| The University of Chicago Medical Centre | Recruiting | Chicago | Illinois | 60637 | United States | Details |
| Tulane Medical center | Recruiting | New Orleans | Louisiana | 70112 | United States | Details |
| MidAmerica Division, Inc., c/o Research Medical Center | Recruiting | Kansas City | Missouri | 64132 | United States | Details |
| Washington University School of Medicine - Siteman Cancer Center | Withdrawn | Saint Louis | Missouri | 63110 | United States | Details |
| UNC Hospitals, The University of North Carolina at Chapel Hill | Recruiting | Chapel Hill | North Carolina | 27599 | United States | Details |
| The Ohio State University Wexner Medical Center/ James Cancer Hospital | Recruiting | Columbus | Ohio | 43210 | United States | Details |
| University of Oklahoma Health Sciences Center - OU Health Stephenson Cancer Center | Recruiting | Oklahoma City | Oklahoma | 73104 | United States | Details |
| Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization | Recruiting | Philadelphia | Pennsylvania | 19107 | United States | Details |
| St. Francis Cancer Center | Recruiting | Greenville | South Carolina | 29607 | United States | Details |
| Prisma Health Cancer Institute | Recruiting | Greenville | South Carolina | 29615 | United States | Details |
| The University of Texas MD Anderson Cancer Center | Recruiting | Houston | Texas | 77030 | United States | Details |
| Princess Alexandra Hospital | Recruiting | Woolloongabba | Queensland | 4102 | Australia | Details |
| Royal Adelaide Hospital | Recruiting | Adelaide | South Australia | 5000 | Australia | Details |
| The Alfred | Recruiting | Melbourne | Victoria | 3004 | Australia | Details |
| Fiona Stanley Hospital | Recruiting | Murdoch | Western Australia | 6150 | Australia | Details |
| Royal Perth Hospital | Recruiting | Perth | Western Australia | 6000 | Australia | Details |
| CHU d'Angers | Recruiting | Angers cedex | 49933 | France | Details | |
| CHU de Caen | Recruiting | Caen cedex | 14033 | France | Details | |
| CHU de Nantes, Hotel Dieu | Recruiting | Nantes | 44093 | France | Details | |
| IUCT Oncopole | Recruiting | Toulouse | 31059 | France | Details | |
| Prince of Wales Hospital, The Chinese University of Hong Kong | Recruiting | Hong Kong | Hong Kong | Details | ||
| Queen Mary Hospital | Recruiting | Hong Kong | Hong Kong | Details | ||
| Oxford University Hospital NHS Foundation Trust | Recruiting | Oxford | OX3 7LE | United Kingdom | Details |