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| NCT ID | NCT04923893 |
| Title | A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5) |
| Acronym | CARTITUDE-5 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Janssen Research & Development, LLC |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NLD | GBR | FRA | ESP | DEU | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCSF | RECRUITING | San Francisco | California | 94143 | United States | Details |
| Yale Cancer Center | RECRUITING | New Haven | Connecticut | 06510 | United States | Details |
| University of Miami Health System | RECRUITING | Miami | Florida | 33136 | United States | Details |
| AdventHealth Cancer Institute | RECRUITING | Orlando | Florida | 32832 | United States | Details |
| University of Iowa Hospitals & Clinics | RECRUITING | Iowa City | Iowa | 52242 | United States | Details |
| University of Kentucky | COMPLETED | Lexington | Kentucky | 40536-0293 | United States | Details |
| Norton Cancer Institute | RECRUITING | Louisville | Kentucky | 40207 | United States | Details |
| University Of Maryland Medical Center | RECRUITING | Baltimore | Maryland | 21201-1595 | United States | Details |
| Beth Israel Deaconess Medical Center | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Barbara Ann Karmanos Cancer Institute | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Henry Ford Cancer Institute | RECRUITING | Detroit | Michigan | 48202-2608 | United States | Details |
| Columbia University Medical Center | RECRUITING | New York | New York | 10032 | United States | Details |
| Memorial Sloan-Kettering Cancer Center | RECRUITING | New York | New York | 10065 | United States | Details |
| New York Presbyterian-Weill Cornell Medical College | RECRUITING | New York | New York | 10065 | United States | Details |
| Levine Cancer Institute | RECRUITING | Charlotte | North Carolina | 28204 | United States | Details |
| Thomas Jefferson University | RECRUITING | Philadelphia | Pennsylvania | 19107 | United States | Details |
| University of Pittsburgh Medical Center | RECRUITING | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| University of Virginia | RECRUITING | Charlottesville | Virginia | 22903 | United States | Details |
| Medical College Of Wisconsin | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Hospital Aleman | RECRUITING | Buenos Aires | C1118AAT | Argentina | Details | |
| Hospital Italiano de Buenos Aires | RECRUITING | Buenos Aires | C1199ABD | Argentina | Details | |
| Hospital Privado Centro Medico de Cordoba | RECRUITING | Cordoba | X5016KEH | Argentina | Details | |
| Royal Prince Alfred Hospital | ACTIVE_NOT_RECRUITING | Camperdown | 2050 | Australia | Details | |
| St. Vincent's Hospital Melbourne | ACTIVE_NOT_RECRUITING | Fitzroy | 3065 | Australia | Details | |
| Austin Health | ACTIVE_NOT_RECRUITING | Heidelberg | 3084 | Australia | Details | |
| Royal Brisbane and Womens Hospital | ACTIVE_NOT_RECRUITING | Herston | 4029 | Australia | Details | |
| Alfred Health | ACTIVE_NOT_RECRUITING | Melbourne | 3004 | Australia | Details | |
| Peter MacCallum Cancer Centre | ACTIVE_NOT_RECRUITING | Melbourne | 8006 | Australia | Details | |
| Fiona Stanley Hospital | ACTIVE_NOT_RECRUITING | Murdoch | 6150 | Australia | Details | |
| Calvary Mater Newcastle Hospital | ACTIVE_NOT_RECRUITING | Waratah | 2298 | Australia | Details | |
| Western Sydney Local Health District | ACTIVE_NOT_RECRUITING | Westmead | 2145 | Australia | Details | |
| Medizinische Universität Graz, LKH-Univ.Klinikum Graz, Klinische Abteilung für Hämatologie | COMPLETED | Graz | 8036 | Austria | Details | |
| Krankenhaus der Elisabethinen Linz | ACTIVE_NOT_RECRUITING | Linz | 4020 | Austria | Details | |
| LKH - Universitätsklinikum der PMU Salzburg | ACTIVE_NOT_RECRUITING | Salzburg | 5020 | Austria | Details | |
| Medical University of Vienna,Universitätsklinik für Innere Medizin I | ACTIVE_NOT_RECRUITING | Vienna | 1090 | Austria | Details | |
| Universitair Ziekenhuis - Antwerpen | ACTIVE_NOT_RECRUITING | Antwerp | 2650 | Belgium | Details | |
| AZ St.-Jan Brugge-Oostende AV | ACTIVE_NOT_RECRUITING | Brugge | 8000 | Belgium | Details | |
| UZ Gent | COMPLETED | Gent | 9000 | Belgium | Details | |
| UZ Leuven | COMPLETED | Leuven | 3000 | Belgium | Details | |
| Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman | COMPLETED | Liege | B-4000 | Belgium | Details | |
| Hospital Sao Rafael | ACTIVE_NOT_RECRUITING | Salvador | 41253-190 | Brazil | Details | |
| Fundacao Antonio Prudente A C Camargo Cancer Center | ACTIVE_NOT_RECRUITING | Sao Paulo | 01509 900 | Brazil | Details | |
| Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein | ACTIVE_NOT_RECRUITING | São Paulo | 05652-900 | Brazil | Details | |
| Tom Baker Cancer Centre | ACTIVE_NOT_RECRUITING | Calgary | Alberta | T2N 4N2 | Canada | Details |
| Vancouver General Hospital | ACTIVE_NOT_RECRUITING | Vancouver | British Columbia | V5Z 1M9 | Canada | Details |
| Juravinski Cancer Centre | ACTIVE_NOT_RECRUITING | Hamilton | Ontario | L8V5C2 | Canada | Details |
| Princess Margaret Cancer Centre University Health Network | ACTIVE_NOT_RECRUITING | Toronto | Ontario | M5G2M9 | Canada | Details |
| Hopital Maisonneuve-Rosemont | ACTIVE_NOT_RECRUITING | Montréal | Quebec | H1T 2M4 | Canada | Details |
| Fakultni nemocnice Brno | RECRUITING | Brno | 625 00 | Czechia | Details | |
| Fakultni nemocnice Hradec Kralove | RECRUITING | Hradec Kralove | 500 05 | Czechia | Details | |
| Fakultni nemocnice Ostrava | RECRUITING | Ostrava - Poruba | 708 52 | Czechia | Details | |
| Vseobecna fakultni nemocnice v Praze | RECRUITING | Praha 2 | 128 08 | Czechia | Details | |
| Aarhus University Hospital | RECRUITING | Aarhus C | 8000 | Denmark | Details | |
| Rigshospitalet | RECRUITING | Copenhagen | 2100 | Denmark | Details | |
| Odense Universitetshospital | RECRUITING | Odense C | 5000 | Denmark | Details | |
| Helsinki University Hospital | ACTIVE_NOT_RECRUITING | Helsinki | 00029 HUS | Finland | Details | |
| Oulu University Hospital | ACTIVE_NOT_RECRUITING | Oulu | 90220 | Finland | Details | |
| Turku University Hospital | ACTIVE_NOT_RECRUITING | Turku | 20520 | Finland | Details | |
| Centre Hospitalier Régional Universitaire de Lille, Hôpital Claude Huriez | ACTIVE_NOT_RECRUITING | Lille Cedex | 59000 | France | Details | |
| C.H.U. Hotel Dieu - France | COMPLETED | Nantes | 44093 | France | Details | |
| Hopital Saint Louis | ACTIVE_NOT_RECRUITING | Paris cedex 10 | 75475 | France | Details | |
| CHU Poitiers - Hôpital la Milétrie | ACTIVE_NOT_RECRUITING | Poitiers | 86021 | France | Details | |
| Institut Universitaire du cancer de Toulouse-Oncopole | ACTIVE_NOT_RECRUITING | Toulouse cedex 9 | 31059 | France | Details | |
| Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin | ACTIVE_NOT_RECRUITING | Berlin | 12203 | Germany | Details | |
| Universitaetsklinikum Carl Gustav Carus TU Dresden | ACTIVE_NOT_RECRUITING | Dresden | 01307 | Germany | Details | |
| Universitatsklinikum Freiburg | ACTIVE_NOT_RECRUITING | Freiburg | 79106 | Germany | Details | |
| Universitaetsklinikum Hamburg Eppendorf | ACTIVE_NOT_RECRUITING | Hamburg | 20246 | Germany | Details | |
| Universitaetsklinikum Heidelberg | ACTIVE_NOT_RECRUITING | Heidelberg | 69120 | Germany | Details | |
| Universitaetsklinikum Leipzig | ACTIVE_NOT_RECRUITING | Leipzig | 04103 | Germany | Details | |
| Universitätsmedizin der Johannes Gutenberg-Universität Mainz | ACTIVE_NOT_RECRUITING | Mainz | 55131 | Germany | Details | |
| Klinikum Großhadern der Ludwig-Maximilians-Universität | ACTIVE_NOT_RECRUITING | München | 81377 | Germany | Details | |
| Universitaetsklinikum Regensburg | ACTIVE_NOT_RECRUITING | Regensburg | 93053 | Germany | Details | |
| Klinikum der Eberhard Karls Universitaet Abt fur innere Med II Haematologie Onkologie Germany | ACTIVE_NOT_RECRUITING | Tubingen | 72076 | Germany | Details | |
| Universitatsklinikum Wurzburg | ACTIVE_NOT_RECRUITING | Wuerzburg | 97080 | Germany | Details | |
| Alexandra General Hospital of Athens | ACTIVE_NOT_RECRUITING | Athens | 11528 | Greece | Details | |
| Attikon University General Hospital of Attica | ACTIVE_NOT_RECRUITING | Athens | 12462 | Greece | Details | |
| G.Papanikolaou | ACTIVE_NOT_RECRUITING | Thessaloniki | 57010 | Greece | Details | |
| Dél-pesti Centrumkórház - Országos Hematológiai és Infektológiai Intézet, Szent László Telephely | RECRUITING | Budapest | 1097 | Hungary | Details | |
| Debreceni Egyetem Klinikai Kozpont | RECRUITING | Debrecen | 4032 | Hungary | Details | |
| St James Hospital | RECRUITING | Dublin | D08 NHY1 | Ireland | Details | |
| Hadassah University Hospita - Ein Kerem | RECRUITING | Jerusalem | P.O.B. 12000 | Israel | Details | |
| Sheba Medical Center Tel Hashomer | RECRUITING | Ramat Gan | 52621 | Israel | Details | |
| Tel Aviv Sourasky Medical Center | RECRUITING | Tel Aviv | 64239 | Israel | Details | |
| Juntendo University Hospital | ACTIVE_NOT_RECRUITING | Bunkyo-Ku | 113-8431 | Japan | Details | |
| Kyushu University Hospital | ACTIVE_NOT_RECRUITING | Fukuoka | 812-8582 | Japan | Details | |
| Hyogo Medical University Hospital | ACTIVE_NOT_RECRUITING | Hyôgo | 663-8501 | Japan | Details | |
| Kanazawa University Hospital | ACTIVE_NOT_RECRUITING | Kanazawa | 920-8641 | Japan | Details | |
| University Hospital Kyoto Perfectural University of Medicine | ACTIVE_NOT_RECRUITING | Kyoto | 602-8566 | Japan | Details | |
| Nagoya City University Hospital | COMPLETED | Nagoya | 467 8602 | Japan | Details | |
| Okayama University Hospital | ACTIVE_NOT_RECRUITING | Okayama | 700-8558 | Japan | Details | |
| Hokkaido University Hospital | ACTIVE_NOT_RECRUITING | Sapporo | 060-8648 | Japan | Details | |
| Tohoku University Hospital | ACTIVE_NOT_RECRUITING | Sendai | 980-8574 | Japan | Details | |
| Japanese Red Cross Medical Center | ACTIVE_NOT_RECRUITING | Shibuya | 150-8935 | Japan | Details | |
| Chonnam National University Hwasun Hospital | ACTIVE_NOT_RECRUITING | Jeollanam-do | 58128 | Korea, Republic of | Details | |
| Seoul National University Hospital | ACTIVE_NOT_RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | ACTIVE_NOT_RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Asan Medical Center | ACTIVE_NOT_RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| Samsung Medical Center | ACTIVE_NOT_RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| The Catholic University of Korea Seoul St. Mary's Hospital | ACTIVE_NOT_RECRUITING | Seoul | 06591 | Korea, Republic of | Details | |
| VU Medisch Centrum | COMPLETED | Amsterdam | 1081 HV | Netherlands | Details | |
| University Medical Center Groningen | ACTIVE_NOT_RECRUITING | Groningen | 9713 GZ | Netherlands | Details | |
| UMC Radboud | ACTIVE_NOT_RECRUITING | Nijmegen | 6500 HB | Netherlands | Details | |
| Erasmus MC | ACTIVE_NOT_RECRUITING | Rotterdam | 3075 EA | Netherlands | Details | |
| Oslo universitetssykehus HF, Rikshospitalet | ACTIVE_NOT_RECRUITING | Oslo | 0372 | Norway | Details | |
| Uniwersyteckie Centrum Kliniczne | ACTIVE_NOT_RECRUITING | Gdansk | 80-214 | Poland | Details | |
| Narodowy Instytut Onkologii im.Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz. w Gliwicach | ACTIVE_NOT_RECRUITING | Gliwice | 44102 | Poland | Details | |
| Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli | ACTIVE_NOT_RECRUITING | Lublin | 20-090 | Poland | Details | |
| Uniwersytecki Szpital Kliniczny w Poznaniu | ACTIVE_NOT_RECRUITING | Poznan | 60-569 | Poland | Details | |
| Instytut Hematologii i Transfuzjologii | ACTIVE_NOT_RECRUITING | Warszawa | 02-776 | Poland | Details | |
| Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu | ACTIVE_NOT_RECRUITING | Wroclaw | 52-007 | Poland | Details | |
| Instituto Portugues de Oncologia | ACTIVE_NOT_RECRUITING | Lisboa | 1099-023 | Portugal | Details | |
| Instituto Portugues de Oncologia | ACTIVE_NOT_RECRUITING | Porto | 4200072 | Portugal | Details | |
| Hosp. de La Santa Creu I Sant Pau | ACTIVE_NOT_RECRUITING | Barcelona | 08025 | Spain | Details | |
| Hosp. Univ. Vall D Hebron | ACTIVE_NOT_RECRUITING | Barcelona | 8035 | Spain | Details | |
| Instituto Catalan Deoncologia Hospital Duran I Reynals | ACTIVE_NOT_RECRUITING | L'Hospitalet de Llobregat | 08908 | Spain | Details | |
| Hosp. Gral. Univ. Gregorio Maranon | ACTIVE_NOT_RECRUITING | Madrid | 28007 | Spain | Details | |
| Hosp. Univ. 12 de Octubre | ACTIVE_NOT_RECRUITING | Madrid | 28041 | Spain | Details | |
| Hosp. Univ. Virgen de La Arrixaca | ACTIVE_NOT_RECRUITING | Murcia | 30120 | Spain | Details | |
| Clinica Univ. de Navarra | ACTIVE_NOT_RECRUITING | Pamplona | 31008 | Spain | Details | |
| Hosp. Clinico Univ. de Salamanca | ACTIVE_NOT_RECRUITING | Salamanca | 37007 | Spain | Details | |
| Hosp. Univ. Marques de Valdecilla | ACTIVE_NOT_RECRUITING | Santander | 39008 | Spain | Details | |
| Hosp. Virgen Del Rocio | ACTIVE_NOT_RECRUITING | Sevilla | 41013 | Spain | Details | |
| Hosp. Univ. I Politecni La Fe | ACTIVE_NOT_RECRUITING | Valencia | 46026 | Spain | Details | |
| Sahlgrenska University Hospital | COMPLETED | Goteborg | 413 45 | Sweden | Details | |
| Universitetssjukhuset | RECRUITING | Linköping | 58185 | Sweden | Details | |
| Skane University Hospital | RECRUITING | Lund | 221 85 | Sweden | Details | |
| Universitatsspital Basel | RECRUITING | Basel | 4031 | Switzerland | Details | |
| INSELSPITAL, Universitätsspital Bern | RECRUITING | Bern | 3010 | Switzerland | Details | |
| Kantonsspital St.Gallen | RECRUITING | St. Gallen | 9007 | Switzerland | Details | |
| University Hospitals Birmingham NHS Trust, | ACTIVE_NOT_RECRUITING | Birmingham | B15 2TH | United Kingdom | Details | |
| Bristol Royal Infirmary | ACTIVE_NOT_RECRUITING | Bristol | BS2 8BJ | United Kingdom | Details | |
| Leeds Teaching Hospitals NHS Trust | ACTIVE_NOT_RECRUITING | Leeds, | LS9 7TF | United Kingdom | Details | |
| University College Hospital | ACTIVE_NOT_RECRUITING | London | NW1 2BU | United Kingdom | Details | |
| King's College Hospital | ACTIVE_NOT_RECRUITING | London | SE5 9RS | United Kingdom | Details | |
| Manchester Royal Infirmary | ACTIVE_NOT_RECRUITING | Manchester | M13 9WL | United Kingdom | Details | |
| The Royal Marsden NHS Trust Sutton | ACTIVE_NOT_RECRUITING | Surrey | SM2 5PT | United Kingdom | Details |