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NCT ID NCT04924101
Title Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99)
Recruitment Recruiting
Gender both
Phase Phase II
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications

lung small cell carcinoma

Therapies

Cisplatin + Etoposide + Lenvatinib + Pembrolizumab

Carboplatin + Etoposide + MK-5890 + Pembrolizumab

Carboplatin + Etoposide + Lenvatinib + Pembrolizumab

Carboplatin + Etoposide + MK-4830 + Pembrolizumab

Cisplatin + Etoposide + MK-5890 + Pembrolizumab

Cisplatin + Etoposide + MK-4830 + Pembrolizumab

Age Groups: adult | senior
Covered Countries USA | ITA | ESP | CAN | AUT

Facility Status City State Zip Country Details
Banner MD Anderson Cancer Center ( Site 0102) Recruiting Gilbert Arizona 85234 United States Details
University of Colorado Anschutz Medical Campus ( Site 0104) Recruiting Aurora Colorado 80045 United States Details
Georgia Cancer Specialists ( Site 0106) Recruiting Atlanta Georgia 30341 United States Details
Parkview Research Center at Parkview Regional Medical Center ( Site 0130) Recruiting Fort Wayne Indiana 46845 United States Details
Baptist Health Lexington-Research ( Site 0108) Recruiting Lexington Kentucky 40503 United States Details
MFSMC-HJWCI-Oncology Research ( Site 0128) Recruiting Baltimore Maryland 21237 United States Details
Oncology Hematology West, PC dba Nebraska Cancer Specialists ( Site 0122) Recruiting Omaha Nebraska 68130 United States Details
Oncology Hematology West, PC dba Nebraska Cancer Specialists ( Site 0129) Recruiting Omaha Nebraska 68130 United States Details
Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 0114) Recruiting Mineola New York 11501 United States Details
Memorial Sloan Kettering Cancer Center ( Site 0115) Recruiting New York New York 10065 United States Details
Cleveland Clinic-Taussig Cancer Center ( Site 0116) Recruiting Cleveland Ohio 44195 United States Details
UPMC Hillman Cancer Center ( Site 0127) Recruiting Pittsburgh Pennsylvania 15232 United States Details
St Francis Cancer Center-Research Office ( Site 0117) Recruiting Greenville South Carolina 29607 United States Details
Virginia Cancer Institute ( Site 0119) Recruiting Richmond Virginia 23229 United States Details
Klinik Penzing-2. Lungenabteilung ( Site 2101) Recruiting Vienna Wien 1140 Austria Details
Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 2100) Recruiting Wien 1210 Austria Details
Hamilton Health Sciences-Juravinski Cancer Centre ( Site 2003) Recruiting Hamilton Ontario L8V 5C2 Canada Details
Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 2005) Recruiting Kingston Ontario K7L 2V7 Canada Details
St. Marys Hospital Center ( Site 2000) Recruiting Montreal Quebec H3T 1M5 Canada Details
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Onkologiai Kozpont ( Site 2800) Recruiting Szolnok Jasz-Nagykun-Szolnok 5004 Hungary Details
Országos Korányi Pulmonológiai Intézet-XIV. Tüdöbelgyógyászat ( Site 2806) Recruiting Budapest Pest 1121 Hungary Details
Torokbalint Tudogyogyintezet-Onkopulmonologiai Jarobeteg Centrum ( Site 2801) Recruiting Törökbálint Pest 2045 Hungary Details
Zala Megyei Szent Rafael Kórház-Pulmonológia ( Site 2805) Recruiting Zalaegerszeg Zala 8900 Hungary Details
Semmelweis University-Pulmonológiai Klinika ( Site 2802) Recruiting Budapest 1083 Hungary Details
Rambam Health Care Campus-Oncology ( Site 2600) Recruiting Haifa 3109601 Israel Details
Shaare Zedek Medical Center ( Site 2602) Recruiting Jerusalem 9103102 Israel Details
Meir Medical Center ( Site 2601) Recruiting Kfar Saba 4428164 Israel Details
Rabin Medical Center-Oncology ( Site 2604) Recruiting Petah Tikva 4941492 Israel Details
Sheba Medical Center-ONCOLOGY ( Site 2603) Recruiting Ramat Gan 5262100 Israel Details
Ospedale San Raffaele-Oncologia Medica ( Site 2303) Recruiting Milano Lombardia 20132 Italy Details
ospedale le scotte-U.O.C. Immunoterapia Oncologica ( Site 2300) Recruiting Siena Toscana 53100 Italy Details
Istituto Europeo di Oncologia IRCCS-Divisione di Oncologia Toracica ( Site 2304) Recruiting Milano 20141 Italy Details
Chungbuk National University Hospital ( Site 1107) Recruiting Cheongju-si Chungbuk 28644 Korea, Republic of Details
Seoul National University Bundang Hospital ( Site 1104) Recruiting Seongnam Kyonggi-do 13620 Korea, Republic of Details
The Catholic University Of Korea St. Vincent's Hospital ( Site 1106) Recruiting Suwon-si Kyonggi-do 16247 Korea, Republic of Details
Seoul National University Hospital ( Site 1101) Recruiting Seoul 03080 Korea, Republic of Details
Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1105) Recruiting Seoul 03722 Korea, Republic of Details
Asan Medical Center-Department of Oncology ( Site 1103) Recruiting Seoul 05505 Korea, Republic of Details
Samsung Medical Center ( Site 1100) Recruiting Seoul 06351 Korea, Republic of Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier Recruiting Warszawa Mazowieckie 02-781 Poland Details
Samodzielny Publiczny Zespó Grulicy i Chorób Puc w Olsztynie-Oddzial Onkologii z Pododdzialem Chemi Recruiting Olsztyn Warminsko-mazurskie 10-357 Poland Details
Krasnoyarsk Regional Oncology Dispensary, Named after Krizhanovsky ( Site 2708) Suspended Krasnoyarsk Krasnoyarskiy Kray 660133 Russian Federation Details
N.N.Petrov Research Institute of Oncology-Department of Chemotherapy and Innovative Technologies ( S Completed Saint Petersburg Sankt-Peterburg 197758 Russian Federation Details
GBUZ "SPb CRPCstmc(o)" ( Site 2705) Suspended Saint-Petersburg Sankt-Peterburg 197758 Russian Federation Details
Scientific research institution of oncology named after N.N. Petrov-Thoracic oncology ( Site 2704) Suspended Sankt-Peterburg 197758 Russian Federation Details
Instituto Catalan de Oncologia - Hospital Duran i Reynals ( Site 2403) Recruiting L'Hospitalet de Llobregat Cataluna 08908 Spain Details
Hospital Insular de Gran Canaria ( Site 2402) Recruiting Las Palmas de Gran Canaria Las Palmas 35001 Spain Details
Hospital Universitari Vall d'Hebron-Oncology ( Site 2401) Recruiting Barcelona 08035 Spain Details
Cantonal Hospital St.Gallen-Oncology & Hematology ( Site 2502) Recruiting st.Gallen Sankt Gallen 9007 Switzerland Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field