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NCT ID NCT05023980
Title A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) (BRUIN CLL-313)
Acronym BRUIN CLL-313
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Loxo Oncology, Inc.
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | NZL | ITA | GBR | FRA | ESP | AUT | AUS

Facility Status City State Zip Country Details
California Research Institute Los Angeles California 90027 United States Details
Innovative Clinical Research Institute Whittier California 90603 United States Details
Oncology-Hematology Associates of West Broward Coral Springs Florida 33065 United States Details
New Jersey Center for Cancer Research Brick New Jersey 08724 United States Details
Clinical Research Alliance, Inc. Westbury New York 11590 United States Details
Liverpool Hospital Liverpool New South Wales 2170 Australia Details
Westmead Hospital Wentworthville New South Wales 2145 Australia Details
Peninsula Private Hospital Frankston Victoria 3199 Australia Details
Uniklinikum Salzburg Salzburg 5020 Austria Details
Klinik Ottakring Vienna 1160 Austria Details
Hospital de Clinicas de Porto Alegre Porto Alegre Rio Grande Do Sul 90035-903 Brazil Details
Irmandade da Santa Casa de Misericórdia de Porto Alegre Porto Alegre Rio Grande Do Sul 90050-170 Brazil Details
Centro Gaucho Integrado - Mae de Deus Center Porto Alegre Rio Grande Do Sul 90110270 Brazil Details
Hemocentro Unicamp Campinas São Paulo 13083-878 Brazil Details
Fundação Doutor Amaral Carvalho Jaú São Paulo 17210120 Brazil Details
UMHAT "Sveti Georgi" EAD Plovdiv 4000 Bulgaria Details
UMHAT 'Sv. Ivan Rilski', EAD Sofia 1431 Bulgaria Details
"SHATHD" EAD, Sofia Sofia 1797 Bulgaria Details
UMHAT - Prof. Dr. Stoyan Kirkovich" AD Stara Zagora 6003 Bulgaria Details
Anhui Provincial Cancer Hospital Hefei Anhui 233004 China Details
Peking University First Hospital Beijing Beijing 100034 China Details
Peking University Third Hospital Beijing Beijing 100191 China Details
The First Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong 510120 China Details
Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430022 China Details
Xiangya Hospital Central South University Changsha Hunan 410008 China Details
Hunan Cancer Hospital Changsha Hunan 410013 China Details
The Affiliated Hospital of Inner Mongolia Medical University Hohhot Inner Mongolia 010050 China Details
The First Affiliated Hospital of Nanchang University Nanchang Jiangxi 330006 China Details
Shengjing Hospital of China Medical University Shenyany Liaoning 110022 China Details
Jiangsu Province Hospital Nanjing Nanjing 210029 China Details
Shanghai Tongren Hospital Changning District Shanghai 200050 China Details
West China Hospital of Sichuan University Chengdu Sichuan 610041 China Details
Institute of hematology&blood disease hospital Tianjin Tianjin 300020 China Details
Tianjin Medical University Cancer Institute and Hospital Tianjin Tianjin 300060 China Details
The First People's Hospital of Hangzhou Linping District Hangzhou Zhejiang 311100 China Details
Beijing Hospital Beijing 100730 China Details
Chongqing Cancer Hospital Chongqing 400030 China Details
Henan Cancer Hospital Zhengzhou 450008 China Details
Fakultni nemocnice Brno Brno 62500 Czechia Details
Fakultni nemocnice Hradec Kralove Hradec Kralove 500 05 Czechia Details
Hospitalier Le Mans Le Mans 72000 France Details
Debreceni Egyetem Orvos-es Egészsegtudomanyi Centrum Debrecen 4032 Hungary Details
SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz Nyíregyháza 4400 Hungary Details
Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz Székesfehérvár 8000 Hungary Details
Irccs Crob Rionero In Vulture Potenza 85028 Italy Details
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII Bergamo 24127 Italy Details
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Brescia 25123 Italy Details
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Meldola 47014 Italy Details
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano 20122 Italy Details
ASST Grande Ospedale Metropolitano Niguarda Comitato Etico Milano Area C Milano 20162 Italy Details
Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo) Monza 20900 Italy Details
Azienda Ospedale Maggiore Della Carita Novara 28100 Italy Details
Istituto di Ematologia-C.R.E.O. (Centro di Ricerche Emato-Oncologich) Perugia 06132 Italy Details
Ospedale Santa Maria delle Croci Ravenna 48020 Italy Details
Azienda Ospedaliera Santa Maria Terni Terni 05100 Italy Details
Azienda sanitaria integrata università di Trieste Trieste 34125 Italy Details
Nagoya City University Hospital Nagoya Aichi 467-8602 Japan Details
Chiba Cancer Center Chiba-Shi Chiba 260-8717 Japan Details
Fukui Medical University Hospital Yoshida-Gun Fukui 910-1193 Japan Details
Hokuyukai Sapporo Hokuyu Hospital Sapporo-shi Hokkaido 0030006 Japan Details
Kochi Medical School Hospital Nankoku Kochi 783-8505 Japan Details
NHO Sendai Medical Center Sendai-shi Miyagi-Ken 9838520 Japan Details
Tohoku University Hospital Sendai-shi Miyagi 980-8574 Japan Details
Dokkyo Medical University - Koshigaya Hospital Koshigaya Saitama 343 8555 Japan Details
University of Yamanashi Hospital Chuo Yamanshi 409-3821 Japan Details
Aomori Prefectural Centeral Hospital Aomori 030-8553 Japan Details
JCHO Kyushu Hospital Fukoka-ken 806 8501 Japan Details
Gachon University Gil Medical Center Namdong-gu Incheon-gwangyeoksi [Incheon] 21565 Korea, Republic of Details
Seoul National University Hospital Seoul Seoul, Korea 03080 Korea, Republic of Details
Severance Hospital, Yonsei University Health System Seoul Seoul-teukbyeolsi [Seoul] 03722 Korea, Republic of Details
Samsung Medical Center Seoul Seoul-teukbyeolsi [Seoul] 06351 Korea, Republic of Details
The Catholic University of Korea-Seoul St. Mary's Hospital Seocho-Gu Seoul 06591 Korea, Republic of Details
Inje Univ Busan Paik Hospital Busan 47392 Korea, Republic of Details
North Shore Hospital, Haematology Research Takapuna Auckland 0622 New Zealand Details
Tauranga Hospital Tauranga Bay Of Plenty 3112 New Zealand Details
Christchurch Hospital Christchurch 8011 New Zealand Details
Middlemore Clinical Trials Papatoetoe 2025 New Zealand Details
Wojewodzki Szpital Specjalistyczny Iwaszkiewicza 5 Legnica 59-220 Poland Details
Klinika Hematoonkologii i Transplantacji Szpiku SPSK1 Lublin Lublin Lubelskie V 20081 Poland Details
Uniwersyteckie Centrum Kliniczne Gdańsk Pomorskie 80214 Poland Details
Centrum Medyczne Pratia Poznan Skorzewo Poznan 60 185 Poland Details
KO-MED Centra Kliniczne Biała Podlaska 21500 Poland Details
Szpital Uniwersytecki nr 1 im. Antoniego Jurasza Bydgoszcz 85-168 Poland Details
Pratia Onkologia Katowice Katowice 40519 Poland Details
Pratia MCM Krakow Kraków 30727 Poland Details
Centrum Onkologii Ziemi Lubelskiej Lublin 20-090 Poland Details
Nasz Lekarz Osrodek Badan Klinicznych Toruń 87-100 Poland Details
Narodowy Instytut Onkologii im. Marii Skłodowskiej-Cuire - Państwowy Instytut Badawczy Warsaw 02781 Poland Details
Uniwersytecki Szpital Kliniczny Klinika Wrocław 50-367 Poland Details
Centro Clínico Académico - Braga (2CA-Braga) (Hospital de Braga) Braga 4710-243 Portugal Details
Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital de Santa Maria Lisboa 1649035 Portugal Details
Instituto Português de Oncologia do Porto Francisco Gentil, EPE Porto 4200-072 Portugal Details
Spitalul Clinic Municipal Filantropia Craiova Craiova Dolj 200143 Romania Details
Institutul Clinic Fundeni - Centrul de Hematologie si Transplant Medular Bucuresti 022328 Romania Details
Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj-Napoca Cluj-Napoca 400015 Romania Details
Institutului Regional de Oncologie IASI Iasi 700483 Romania Details
Academician I.P. Pavlov First St-Petersburg State Medical University St-Petersburg 197022 Russian Federation Details
Hospital Universitario Central de Asturias Oviedo Asturias 33011 Spain Details
Hospital Universitario HM Sanchinarro Madrid Madrid, Comunidad De 28050 Spain Details
Hospital de la Santa Creu i Sant Pau Barcelona 08041 Spain Details
Hospital Universitario Fundación Jiménez Díaz Madrid 28040 Spain Details
Hospital Universitario Virgen del Rocío Sevilla 41013 Spain Details
Hospital Universitario Virgen de Valme Sevilla 41014 Spain Details
Chang Bing Show Chwan Memorial Hospital Changhua 50544 Taiwan Details
China Medical University Hospital Taichung 40447 Taiwan Details
National Taiwan University Hospital Taipei 10002 Taiwan Details
Chang Gung Memorial Hospital - Linkou Taoyuan City 333 Taiwan Details
Birmingham Heartlands Hospital Birmingham England B9 5SS United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field