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| NCT ID | NCT05104866 |
| Title | A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | Duarte | California | 91010 | United States | Details | |
| Research Site | Los Angeles | California | 90095 | United States | Details | |
| Research Site | Palo Alto | California | 94305-5826 | United States | Details | |
| Research Site | San Francisco | California | 94143 | United States | Details | |
| Research Site | Jacksonville | Florida | 32207 | United States | Details | |
| Research Site | Atlanta | Georgia | 30322 | United States | Details | |
| Research Site | Boston | Massachusetts | 02114 | United States | Details | |
| Research Site | Boston | Massachusetts | 02215 | United States | Details | |
| Research Site | Grand Rapids | Michigan | 49503 | United States | Details | |
| Research Site | New York | New York | 10065 | United States | Details | |
| Research Site | Cleveland | Ohio | 44119 | United States | Details | |
| Research Site | Portland | Oregon | 97239 | United States | Details | |
| Research Site | Nashville | Tennessee | 37203 | United States | Details | |
| Research Site | Richmond | Virginia | 23219 | United States | Details | |
| Research Site | Caba | 1414 | Argentina | Details | ||
| Research Site | Caba | C1280AEB | Argentina | Details | ||
| Research Site | La Plata | 1900 | Argentina | Details | ||
| Research Site | Mar del Plata | 7600 | Argentina | Details | ||
| Research Site | Rosario | 2000 | Argentina | Details | ||
| Research Site | Rosario | 2123 | Argentina | Details | ||
| Research Site | Anderlecht | 1070 | Belgium | Details | ||
| Research Site | Leuven | 3000 | Belgium | Details | ||
| Research Site | Liège | 4000 | Belgium | Details | ||
| Research Site | Itajai | 88310-110 | Brazil | Details | ||
| Research Site | Jau | 17210-070 | Brazil | Details | ||
| Research Site | Porto Alegre | 90035903 | Brazil | Details | ||
| Research Site | Ribeirão Preto | 14051-140 | Brazil | Details | ||
| Research Site | Rio de Janeiro | 20560-120 | Brazil | Details | ||
| Research Site | Sao Paulo | 01236-030 | Brazil | Details | ||
| Research Site | Sao Paulo | 01246-000 | Brazil | Details | ||
| Research Site | Sao Paulo | 01509-900 | Brazil | Details | ||
| Research Site | Sao Paulo | 1323001 | Brazil | Details | ||
| Research Site | North York | Ontario | M2K 1E1 | Canada | Details | |
| Research Site | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Research Site | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Research Site | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Research Site | Quebec | G1S 4L8 | Canada | Details | ||
| Research Site | Baoding | 071000 | China | Details | ||
| Research Site | Beijing | 100044 | China | Details | ||
| Research Site | Beijing | 100071 | China | Details | ||
| Research Site | Beijing | 100210 | China | Details | ||
| Research Site | Bengbu | 233060 | China | Details | ||
| Research Site | Changchun | 130021 | China | Details | ||
| Research Site | Changsha | 410013 | China | Details | ||
| Research Site | Chengdu | 610000 | China | Details | ||
| Research Site | Guangzhou | 510060 | China | Details | ||
| Research Site | Hangzhou | 310003 | China | Details | ||
| Research Site | Hangzhou | 310020 | China | Details | ||
| Research Site | Hangzhou | 310022 | China | Details | ||
| Research Site | Harbin | 150049 | China | Details | ||
| Research Site | Jinan | 250001 | China | Details | ||
| Research Site | Jinan | 250117 | China | Details | ||
| Research Site | Linyi | 276000 | China | Details | ||
| Research Site | Nanchang | 330006 | China | Details | ||
| Research Site | Nanchang | 330009 | China | Details | ||
| Research Site | Shanghai | 200000 | China | Details | ||
| Research Site | Tianjin | 300060 | China | Details | ||
| Research Site | Xiamen | 361003 | China | Details | ||
| Research Site | Bezannes | 51430 | France | Details | ||
| Research Site | Bordeaux | 33030 | France | Details | ||
| Research Site | Lille | 59000 | France | Details | ||
| Research Site | Lyon | 69008 | France | Details | ||
| Research Site | Montpellier | 34070 | France | Details | ||
| Research Site | Plerin | 22190 | France | Details | ||
| Research Site | Toulouse Cedex 09 | 31059 | France | Details | ||
| Research Site | Villejuif | 94800 | France | Details | ||
| Research Site | Heidelberg | 69120 | Germany | Details | ||
| Research Site | Homburg | 66421 | Germany | Details | ||
| Research Site | Leipzig | 4103 | Germany | Details | ||
| Research Site | München | 80637 | Germany | Details | ||
| Research Site | Ravensburg | 88212 | Germany | Details | ||
| Research Site | Budapest | 1062 | Hungary | Details | ||
| Research Site | Budapest | 1122 | Hungary | Details | ||
| Research Site | Szekszárd | 7100 | Hungary | Details | ||
| Research Site | Szolnok | 5000 | Hungary | Details | ||
| Research Site | Gurgaon | 122001 | India | Details | ||
| Research Site | Howrah | 711103 | India | Details | ||
| Research Site | Hyderabad | 500084 | India | Details | ||
| Research Site | JAipur | 302022 | India | Details | ||
| Research Site | Kolkata | 700160 | India | Details | ||
| Research Site | Nashik | 422009 | India | Details | ||
| Research Site | Surat | 395002 | India | Details | ||
| Research Site | Vishakhapatnam | 530017 | India | Details | ||
| Research Site | Bologna | 40138 | Italy | Details | ||
| Research Site | Candiolo | 10060 | Italy | Details | ||
| Research Site | Firenze | 50139 | Italy | Details | ||
| Research Site | Meldola | 47014 | Italy | Details | ||
| Research Site | Milano | 20132 | Italy | Details | ||
| Research Site | Milan | 20141 | Italy | Details | ||
| Research Site | Napoli | 80131 | Italy | Details | ||
| Research Site | Padova | 35128 | Italy | Details | ||
| Research Site | Prato | 59100 | Italy | Details | ||
| Research Site | Roma | 00168 | Italy | Details | ||
| Research Site | Chuo-ku | 104-0045 | Japan | Details | ||
| Research Site | Fukuoka | 811-1395 | Japan | Details | ||
| Research Site | Fukushima-shi | 960-1295 | Japan | Details | ||
| Research Site | Hiroshima-shi | 730-8518 | Japan | Details | ||
| Research Site | Isehara-shi | 259-1193 | Japan | Details | ||
| Research Site | Kagoshima-shi | 892-0833 | Japan | Details | ||
| Research Site | Kashiwa | 227-8577 | Japan | Details | ||
| Research Site | Kitaadachi-gun | 362-0806 | Japan | Details | ||
| Research Site | Koto-ku | 135-8550 | Japan | Details | ||
| Research Site | Kyoto-shi | 606-8507 | Japan | Details | ||
| Research Site | Matsuyama-shi | 791-0280 | Japan | Details | ||
| Research Site | Nagoya-shi | 464-8681 | Japan | Details | ||
| Research Site | Nishinomiya-shi | 663-8501 | Japan | Details | ||
| Research Site | Osaka-shi | 541-8567 | Japan | Details | ||
| Research Site | Osakasayama-shi | 589-8511 | Japan | Details | ||
| Research Site | Sapporo-shi | 003-0804 | Japan | Details | ||
| Research Site | Shinagawa-ku | 142-8666 | Japan | Details | ||
| Research Site | Shinjuku-ku | 162-8655 | Japan | Details | ||
| Research Site | Yokohama-shi | 241-8515 | Japan | Details | ||
| Research Site | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Research Site | Seoul | 02841 | Korea, Republic of | Details | ||
| Research Site | Seoul | 03080 | Korea, Republic of | Details | ||
| Research Site | Seoul | 03722 | Korea, Republic of | Details | ||
| Research Site | Seoul | 05505 | Korea, Republic of | Details | ||
| Research Site | Seoul | 06351 | Korea, Republic of | Details | ||
| Research Site | Seoul | 6273 | Korea, Republic of | Details | ||
| Research Site | Amsterdam | 1081 HV | Netherlands | Details | ||
| Research Site | Rotterdam | 3083 AN | Netherlands | Details | ||
| Research Site | Venlo | 5912 BL | Netherlands | Details | ||
| Research Site | Białystok | 15-027 | Poland | Details | ||
| Research Site | Gdansk | 80-952 | Poland | Details | ||
| Research Site | Gdynia | 81-519 | Poland | Details | ||
| Research Site | Konin | 62-500 | Poland | Details | ||
| Research Site | Koszalin | 75-581 | Poland | Details | ||
| Research Site | Tomaszów Mazowiecki | 97-200 | Poland | Details | ||
| Research Site | Warszawa | 02-781 | Poland | Details | ||
| Research Site | Łódź | 90-302 | Poland | Details | ||
| Research Site | Moscow | 115478 | Russian Federation | Details | ||
| Research Site | Moscow | 143423 | Russian Federation | Details | ||
| Research Site | George | 6529 | South Africa | Details | ||
| Research Site | Johannesburg | 2013 | South Africa | Details | ||
| Research Site | Johannesburg | 2196 | South Africa | Details | ||
| Research Site | Port Elizabeth | 6045 | South Africa | Details | ||
| Research Site | Pretoria | 0081 | South Africa | Details | ||
| Research Site | A Coruña | 15006 | Spain | Details | ||
| Research Site | Barcelona | 08028 | Spain | Details | ||
| Research Site | Barcelona | 8036 | Spain | Details | ||
| Research Site | Bilbao (Vizcaya) | 48013 | Spain | Details | ||
| Research Site | Huelva | 21005 | Spain | Details | ||
| Research Site | L'Hospitalet de Llobregat | 08908 | Spain | Details | ||
| Research Site | Madrid | 28034 | Spain | Details | ||
| Research Site | Madrid | 28040 | Spain | Details | ||
| Research Site | Malaga | 29010 | Spain | Details | ||
| Research Site | Sevilla | 41013 | Spain | Details | ||
| Research Site | Valencia | 46010 | Spain | Details | ||
| Research Site | Kaohsiung | 82445 | Taiwan | Details | ||
| Research Site | Kaohsiung | 833 | Taiwan | Details | ||
| Research Site | Taichung | 40447 | Taiwan | Details | ||
| Research Site | Tainan | 70403 | Taiwan | Details | ||
| Research Site | Taipei City | 10050 | Taiwan | Details | ||
| Research Site | Taipei | 10449 | Taiwan | Details | ||
| Research Site | Taipei | 11217 | Taiwan | Details | ||
| Research Site | Taoyuan | 333 | Taiwan | Details | ||
| Research Site | Blackpool | FY3 8NR | United Kingdom | Details | ||
| Research Site | Bristol | BS2 8ED | United Kingdom | Details | ||
| Research Site | Cardiff | CF14 2TL | United Kingdom | Details | ||
| Research Site | Colchester | CO4 5JL | United Kingdom | Details | ||
| Research Site | Edinburgh | EH4 2XU | United Kingdom | Details | ||
| Research Site | London | EC1A 7BE | United Kingdom | Details | ||
| Research Site | London | SW3 6JJ | United Kingdom | Details | ||
| Research Site | Manchester | M20 4BX | United Kingdom | Details | ||
| Research Site | Nottingham | NG5 1PB | United Kingdom | Details | ||
| Research Site | Sutton | SM2 5PT | United Kingdom | Details | ||
| Research Site | Truro | TR1 3LJ | United Kingdom | Details |