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| NCT ID | NCT05309668 |
| Title | Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged >/=1 to <7 Years With NF1-related Symptomatic, Inoperable PN (SPRINKLE) |
| Acronym | SPRINKLE |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | child |
| Covered Countries | USA | NLD | ITA | ESP | DEU |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Phoenix Children's Hospital | RECRUITING | Phoenix | Arizona | 85060 | United States | Details |
| University of Indiana (IU) Health - Riley Hospital for Children | RECRUITING | Indianapolis | Indiana | 46202 | United States | Details |
| Childrens Hospital Medical Center - Akron | RECRUITING | Akron | Ohio | 44308 | United States | Details |
| Children's Hospital of Philadelphia | RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Texas Children's Hospital | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Children's Hospital of Richmond at VCU | RECRUITING | Richmond | Virginia | 23219 | United States | Details |
| Research Site | RECRUITING | Berlin | 13353 | Germany | Details | |
| Research Site | RECRUITING | Hamburg | 20246 | Germany | Details | |
| Research Site | RECRUITING | Munchen | 80337 | Germany | Details | |
| Research Site | RECRUITING | Tubingen | 72076 | Germany | Details | |
| Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | RECRUITING | Milano | 20133 | Italy | Details | |
| Ospedale Pediatrico Bambino Gesu' di Roma | RECRUITING | Roma | 00165 | Italy | Details | |
| Ospedale Infantile Regina Margherita | RECRUITING | Torino | 10126 | Italy | Details | |
| Nagoya University Hospital | RECRUITING | Nagoya-shi | 466-8560 | Japan | Details | |
| National Center for Child Health and Development | RECRUITING | Setagaya-ku | 157-8535 | Japan | Details | |
| Oita University Hospital | RECRUITING | Yufu-shi | 879-5593 | Japan | Details | |
| Erasmus University Medical Center Rotterdam | WITHDRAWN | Rotterdam | 3015 GD | Netherlands | Details | |
| Research Site | SUSPENDED | Moscow | 119620 | Russian Federation | Details | |
| Research Site | SUSPENDED | Moscow | 125412 | Russian Federation | Details | |
| Hospital Sant Joan de Deu | RECRUITING | Barcelona | 08950 | Spain | Details | |
| Hospital General Universitario Gregorio Marañón | RECRUITING | Madrid | 28007 | Spain | Details |