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| NCT ID | NCT05340621 |
| Title | NAUTILUS: OKI-179 Plus Binimetinib in Patients With Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | OnKure, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| CTCA Phoenix, part of City of Hope | Phoenix | Arizona | 85027 | United States | Details | |
| University of California, San Francisco | San Francisco | California | 94143 | United States | Details | |
| University of Florida Health Cancer Center | Gainesville | Florida | 32610 | United States | Details | |
| Emory University Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| CTCA Atlanta, part of City of Hope | Newnan | Georgia | 30265 | United States | Details | |
| CTCA Chicago, part of City of Hope | Zion | Illinois | 60099 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Virginia Health System | Charlottesville | Virginia | 22908 | United States | Details |