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| NCT ID | NCT05502237 |
| Title | Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer (STAR-121) |
| Acronym | STAR-121 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Gilead Sciences |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Palo Verde Hematology Oncology Ltd | RECRUITING | Glendale | Arizona | 85304 | United States | Details |
| California Cancer Associates for Research and Excellence | RECRUITING | San Marcos | California | 92069 | United States | Details |
| Texas Oncology | RECRUITING | Santa Barbara | California | 93105 | United States | Details |
| Innovative Clinical Research Institute | RECRUITING | Whittier | California | 90606 | United States | Details |
| Eastern CT Hematology and Oncology Associates | RECRUITING | Norwich | Connecticut | 06360 | United States | Details |
| Lake City Cancer Care | RECRUITING | Lake City | Florida | 32024 | United States | Details |
| Florida Cancer Specialists | RECRUITING | Sarasota | Florida | 34232 | United States | Details |
| Moffitt Cancer Center | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| Peachtree Hematology Oncology Consultants | RECRUITING | Atlanta | Georgia | 30318 | United States | Details |
| Illinois Cancer Care | RECRUITING | Peoria | Illinois | 61615 | United States | Details |
| Messino Cancer Centers | RECRUITING | Asheville | North Carolina | 28806 | United States | Details |
| Oncology Hematology Care, Inc. | RECRUITING | Cincinnati | Ohio | 45242 | United States | Details |
| Hematology & Oncology Associates | RECRUITING | Eugene | Oregon | 97401 | United States | Details |
| AHN Allegheny General Hospital | RECRUITING | Pittsburgh | Pennsylvania | 15212 | United States | Details |
| Arlington Cancer Center | RECRUITING | Arlington | Texas | 76012 | United States | Details |
| Texas Oncology - Austin | RECRUITING | Austin | Texas | 78745 | United States | Details |
| Texas Oncology | RECRUITING | Dallas | Texas | 75246 | United States | Details |
| Texas Oncology- Denison | RECRUITING | Sherman | Texas | 75090 | United States | Details |
| US Oncology Investigational Products Center (IPC) | RECRUITING | Arlington | Virginia | 22205 | United States | Details |
| Oncology and Hematology Associates of Southwest Virginia, Inc | RECRUITING | Blacksburg | Virginia | 24060 | United States | Details |
| Northwest Cancer Specialists, PC | RECRUITING | Vancouver | Washington | 98684 | United States | Details |
| Investigaciones CORI S.R.L. | RECRUITING | Capital | F5300COE | Argentina | Details | |
| Centro Médico Privado Centro de Especialidades Médicas Ambulatorias e Investigación Clínica | RECRUITING | Cardoba | X5008HHW | Argentina | Details | |
| Centro Medico Barrio Parque | RECRUITING | Ciudad Autanoma Buenos Aires | 1426 | Argentina | Details | |
| Sanatorio Allende | RECRUITING | Cordoba | 5000 | Argentina | Details | |
| Sanatorio Britanico de Rosario | RECRUITING | Rosario | 2000 | Argentina | Details | |
| Sanatorio Parque de Rosario | RECRUITING | Rosario | S2000DSV | Argentina | Details | |
| Hospital Provincial del Centenario | RECRUITING | Rosario | S2002KDS | Argentina | Details | |
| Instituto Medico de la Fundacion Estudios Clinicos | RECRUITING | Rosario | S2013DTC | Argentina | Details | |
| CAIPO - Centro para la Atención Integral del Paciente Oncológico | RECRUITING | San Miguel de Tucumán | 4000 | Argentina | Details | |
| Clínica Viedma | RECRUITING | Viedma | 8500 | Argentina | Details | |
| Klinikum Klagenfurt am Woerthersee | RECRUITING | Klagenfurt Am Woerthersee | Austria | Details | ||
| Ordensklinikum Linz GmbH, Elisabethinen | RECRUITING | Linz | 4020 | Austria | Details | |
| Klinikum Wels-Grieskirchen | RECRUITING | Wels | 4600 | Austria | Details | |
| Krankenhaus Nord - Klinik Floridsdorf | RECRUITING | Wien | A-1140 | Austria | Details | |
| Algemeen Ziekenhuis Sint-Lucas | RECRUITING | Aalst | 9300 | Belgium | Details | |
| Grand Hopital de Charleroi asbl (GHdC) | RECRUITING | Charleroi | 6000 | Belgium | Details | |
| AZ Sint-Maarten | RECRUITING | Mechelen | 2800 | Belgium | Details | |
| CHU UCL Namur / Site Sainte Elisabeth | RECRUITING | Namur | 5000 | Belgium | Details | |
| Cenantron Centro Avançado de Tratamento Oncologico Ltda | RECRUITING | Belo Horizonte | 30130-090 | Brazil | Details | |
| Hospital Evangelico de Cachoeiro de Itapemirim | RECRUITING | Cachoeiro De Itapemirim | 29308-014 | Brazil | Details | |
| Fundacao Universidade De Caxias Do Sul - FUCS/RS | RECRUITING | Caxias Do Sul | 95070-560 | Brazil | Details | |
| Instituto do Câncer do Ceará - ICC | RECRUITING | Fortaleza | 60430-230 | Brazil | Details | |
| Oncosite - Centro de Pesquisa Clinica em Oncologia LTDA | RECRUITING | Ijui | 98700-000 | Brazil | Details | |
| Centro Des Pesquisas Clinicas da Fundacao Doutor Amaral Carvalho | RECRUITING | Jau | 17210080 | Brazil | Details | |
| Irmandade da Santa Casa de Misericordia de Porto Alegre | RECRUITING | Porto Alegre | 90020-090 | Brazil | Details | |
| Hospital de Clínicas de Porto Alegre | RECRUITING | Porto Alegre | 90035-903 | Brazil | Details | |
| Hospital São Lucas da PUCRS | RECRUITING | Porto Alegre | 90610-000 | Brazil | Details | |
| Hospital Ana Nery Santa Cruz do Sul | RECRUITING | Santa Cruz Do Sul | 96810-110 | Brazil | Details | |
| Instituto Brasiliero de Controle do Cancer IBCC | RECRUITING | Sao Paulo | 03102002 | Brazil | Details | |
| Centre Integre de sante et de services sociaux de la Monteregie Centre | RECRUITING | Greenfield Park | J4V 2H1 | Canada | Details | |
| Moncton Hospital | RECRUITING | Moncton | E1C 6Z8 | Canada | Details | |
| CISSS des Laurentides | RECRUITING | Quebec | J7Z 2V4 | Canada | Details | |
| Centre de santé et services sociaux de Rimouski-Neigette | RECRUITING | Rimouski | G5L5T1 | Canada | Details | |
| BC Cancer - Victoria | WITHDRAWN | Victoria | V8R 6V5 | Canada | Details | |
| Clinica Alemana de Santiago | RECRUITING | Las Condes | 7550000 | Chile | Details | |
| Orlandioncologia | RECRUITING | Providencia | 7500006 | Chile | Details | |
| Oncovida- Santiago | RECRUITING | Providencia | 7510035 | Chile | Details | |
| Clinica Puerto Montt | RECRUITING | Puerto Montt | 5500243 | Chile | Details | |
| Biocinetic | RECRUITING | Santiago | 8331143 | Chile | Details | |
| James Lind Centro de Investigacion del Cancer | RECRUITING | Temuco | 4800827 | Chile | Details | |
| Oncocentro APYS | RECRUITING | Vina del Mar | 2520612 | Chile | Details | |
| Shanghai Pulmonary Hospital | RECRUITING | Shanghai | 200433 | China | Details | |
| The First Affiliated Hospital of Xinxiang Medical College | RECRUITING | Xinxiang | 453100 | China | Details | |
| Ambroise-Pare Hospital, Assistance Publique - Hopitaux de Paris | RECRUITING | Boulogne-Billancourt | 92100 | France | Details | |
| CHU de Caen | RECRUITING | Caen | 14000 | France | Details | |
| Clinique Victor Hugo, Centre de Cancerologie de la Sarthe | RECRUITING | Le Mans | 72000 | France | Details | |
| Hopital Nord | RECRUITING | Marseille | 13005 | France | Details | |
| Institut de Cancer de Montpellier (ICM) - Val d'Aurelle | RECRUITING | Montpellier | 34928 | France | Details | |
| Centre Antoine Lacassagne | RECRUITING | Nice | 6189 | France | Details | |
| Institut de cancerologie de l'ouest (ICO) | RECRUITING | Saint-Herblain | 44805 | France | Details | |
| Hopital d'Instruction des Armees (HIA) Begin | RECRUITING | Saint-Mandé | 94160 | France | Details | |
| Centre Hospitalier de Saint-Quentin | RECRUITING | Saint-Quentin | 2100 | France | Details | |
| Institut de Cancerologie Strasbourg Europe (ICANS) | RECRUITING | Strasbourg | 67033 | France | Details | |
| Hôpital Foch | RECRUITING | Suresnes | 92150 | France | Details | |
| CHI de Toulon la Seyne-sur-Mer Hopital Sainte Musse | RECRUITING | Toulon cedex | 83056 | France | Details | |
| Augusta-Kranken-Anstalt gGmbh Klinik für Hämatologie Onkologie und Palliativmedizin | RECRUITING | Bochum | 44791 | Germany | Details | |
| Klinikum Chemnitz gGmbH | RECRUITING | Chemnitz | 9116 | Germany | Details | |
| Universitatsklinikum Essen / Westdeutsches Tumorzentrum, Innere Klinik (Tumorforschung) | RECRUITING | Essen | 45122 | Germany | Details | |
| Universitätsklinikum Freiburg, Klinik für Innere Medizin I Hämatologie, Onkologie und Stammzelltransplantation | RECRUITING | Freiburg | 79106 | Germany | Details | |
| LungenClinic Grosshansdorf | RECRUITING | Grosshansdorf | 22927 | Germany | Details | |
| Krankenhaus Martha-Maria Halle Dölau | RECRUITING | Halle | 06120 | Germany | Details | |
| Asklepios Kliniken Hamburg | RECRUITING | Hamburg | 21075 | Germany | Details | |
| Katholisches Marienkrankenhaus gGmbH | RECRUITING | Hamburg | 22087 | Germany | Details | |
| Lungenklinik Hemer, Zentrum fur Pneumologie and Thoraxchirurgie | RECRUITING | Hemer | 58675 | Germany | Details | |
| Vincentius-Diakonissen-Kliniken gAG, St. Vincentius-Kliniken, Medizinische Klinik 2 | RECRUITING | Karlsruhe | 76137 | Germany | Details | |
| Klinikum Kassel | RECRUITING | Kassel | 34125 | Germany | Details | |
| Kliniken der Stadt Köln ggmbh, Krankenhaus Koln-Merheim/Lungenklinik | RECRUITING | Köln | 51109 | Germany | Details | |
| Universitatsklinikum Schleswig-Holstein | RECRUITING | Lubeck | 23538 | Germany | Details | |
| Johannes Wesling Klinikum Minden | RECRUITING | Minden | 32429 | Germany | Details | |
| Munchen Klinik Bogenhausen, Klinik fur Pneumologie und Pneumologische Onkologie | RECRUITING | Munchen | 81925 | Germany | Details | |
| Queen Elizabeth Hospital | RECRUITING | Hong Kong | 999077 | Hong Kong | Details | |
| Queen Mary Hospital | RECRUITING | Hong Kong | Hong Kong | Details | ||
| Prince of Wales Hospital | RECRUITING | New Territories | Hong Kong | Details | ||
| Soroka University Medical Center, Itzchak Rager Blvd. | RECRUITING | Beer Seva | 84101 | Israel | Details | |
| Shaare Zedek Medical Center | RECRUITING | Jerusalem | 9103102 | Israel | Details | |
| Oncology Institute, Galilee Medical Center, Route 89 Nahariya-Cabri | RECRUITING | Nahariya | Israel | Details | ||
| Rabin Medical Center | RECRUITING | Petah Tiqva | 49100 | Israel | Details | |
| Kaplan Medical Center | RECRUITING | Rehovot | 76100 | Israel | Details | |
| Tel-Aviv Sourasky Medical Center | RECRUITING | Tel Aviv | 64239 | Israel | Details | |
| Azienda Ospedaliera San Giuseppe Moscati | RECRUITING | Avellino | Italy | Details | ||
| IRCCS Fondazoine del Piemonte per l'Oncologia | RECRUITING | Candiolo | 10060 | Italy | Details | |
| Azienda Socio Sanitaria Territoriale di Cremona | RECRUITING | Cremona | 26100 | Italy | Details | |
| Ospedale Policlinico San Martino | RECRUITING | Genova | 16132 | Italy | Details | |
| Ospedale San Raffaele | RECRUITING | Milano | 20132 | Italy | Details | |
| Azienda Ospedaliero Universitaria di Modena | RECRUITING | Modena | 41124 | Italy | Details | |
| AORN Cardarelli | RECRUITING | Naples | 80131 | Italy | Details | |
| Azienda Ospedaliera dei Colli | RECRUITING | Napoli | 80131 | Italy | Details | |
| IRCCS Policlinico S. Matteo, Dipartimento Oncologia Ematologia-Oncologia Medica | RECRUITING | Pavia | 27100 | Italy | Details | |
| Azienda Sanitaria Territoriale Pesaro e Urbino (AST) | RECRUITING | Pesaro | 61122 | Italy | Details | |
| Ospedale Guglielmo da Saliceto AUSL di Piacenza | RECRUITING | Piacenza | 29100 | Italy | Details | |
| Centro di Riferimento Oncologico | RECRUITING | Pordenone | 33081 | Italy | Details | |
| Regina Elena Institute for Cancer Research | RECRUITING | Rome | 00144 | Italy | Details | |
| ASST Bergamo Ovest- ospedale di Treviglio | RECRUITING | Treviglio | 24047 | Italy | Details | |
| National Cancer Center Hospital East | RECRUITING | Chiba | 277-0882 | Japan | Details | |
| National Hospital Organization Shikoku Cancer Center | RECRUITING | Ehime | 791-0280 | Japan | Details | |
| Kyushu University Hospital | RECRUITING | Fukuoka | 812-8582 | Japan | Details | |
| Kurume University Hospital | RECRUITING | Fukuoka | 830-0011 | Japan | Details | |
| National Hospital Organization Himeji Medical Center | RECRUITING | Hyogo | 670-8520 | Japan | Details | |
| Hyogo Cancer Center | RECRUITING | Hyogo | 673-8558 | Japan | Details | |
| Kanazawa University Hospital | RECRUITING | Ishikawa | 920-8641 | Japan | Details | |
| Kanagawa Cancer Center | RECRUITING | Kanagawa | 241-0815 | Japan | Details | |
| Sendai Kousei Hospital | RECRUITING | Miyagi | 980-0873 | Japan | Details | |
| Niigata Cancer Center Hospital | RECRUITING | Niigata | 951-8566 | Japan | Details | |
| Osaka Metropolitan University Hospital | RECRUITING | Osaka | 545-8586 | Japan | Details | |
| Osaka Medical and Pharmaceutical University Hospital | RECRUITING | Osaka | 569-8686 | Japan | Details | |
| Kindai University Hospital | RECRUITING | Osaka | 589-8511 | Japan | Details | |
| National Hospital Organization Kinki Chuo Chest Medical Center | RECRUITING | Osaka | 591-8555 | Japan | Details | |
| Saitama Medical University | RECRUITING | Saitama | 350-1298 | Japan | Details | |
| SMG - SNU Boramae Medical Center | RECRUITING | Dongjak-Gu | 07061 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Gangnam-Gu | 6351 | Korea, Republic of | Details | |
| National Cancer Center | RECRUITING | Goyang | 410769 | Korea, Republic of | Details | |
| Chungbuk National University Hospital | RECRUITING | Heungdeok-Gu | 361-711 | Korea, Republic of | Details | |
| Inha University Hospital | RECRUITING | Incheon | 22332 | Korea, Republic of | Details | |
| Gachon University Gil Medical Center | RECRUITING | Inchon | 21565 | Korea, Republic of | Details | |
| Kosin University Gospel Hospital | RECRUITING | Seo-gu | 49267 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Asan Medical Center | RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| The Catholic University of Korea, Seoul St. Mary's Hospital | RECRUITING | Seoul | 06591 | Korea, Republic of | Details | |
| Ajou University Hospital | RECRUITING | Suwon-si | 16499 | Korea, Republic of | Details | |
| The Catholic University of Korea, Saint Vincent's Hospital | RECRUITING | Suwon | 16247 | Korea, Republic of | Details | |
| Health Pharma Professional Research S.A. de C.V. | RECRUITING | Mexico | 3100 | Mexico | Details | |
| Hospital Universitario Dr. Jose Eleuterio Gonzalez | RECRUITING | Mitras Centro | 64460 | Mexico | Details | |
| Oaxaca Site Management Organization | RECRUITING | Oaxaca | 68000 | Mexico | Details | |
| Centro de Investigacion Clinica de Oaxaca | RECRUITING | Oaxaca | 68020 | Mexico | Details | |
| Clinical Medical Research SC. | RECRUITING | Orizaba Centro | 94300 | Mexico | Details | |
| Clinica Integral Internacional de Oncologia S de RL de CV | RECRUITING | Puebla | 72530 | Mexico | Details | |
| FAICIC Clínical Research | RECRUITING | Veracruz | 91900 | Mexico | Details | |
| Amphia Ziekenhuis | RECRUITING | Breda | 4818 CK | Netherlands | Details | |
| Ziekenhuis Gelderse Vallei | RECRUITING | Ede | 6716 RP | Netherlands | Details | |
| Universitair Medisch Centrum Groningen | RECRUITING | Groningen | 9713 GZ | Netherlands | Details | |
| Ziekenhuis St Jansdal | RECRUITING | Harderwijk | 3844 DG | Netherlands | Details | |
| TweeSteden Ziekenhuis | RECRUITING | Tilburg | Netherlands | Details | ||
| Hospital Prof. Doutor Fernando Fonseca | RECRUITING | Amadora | 2720276 | Portugal | Details | |
| Instituto Português de Oncologia de Lisboa Francisco Gentil | RECRUITING | Lisboa | 1089 | Portugal | Details | |
| Fundacao Champalimaud | RECRUITING | Lisboa | 1400-038 | Portugal | Details | |
| Centro Hospitalar Universitário Lisboa Norte - Hospital Pulido Valente | RECRUITING | Lisboa | Portugal | Details | ||
| Hospital Beatriz Angelo. Hospital de Loures. | RECRUITING | Lisbon | 2674-514 | Portugal | Details | |
| Centro Hospitalar Universitario Sao Joao, EPE | RECRUITING | Porto | 4202-451 | Portugal | Details | |
| Unidade Local de Saude de Matosinhos EPE - Hospital Pedro Hispano SA | RECRUITING | Senhora da Hora | 4464-513 | Portugal | Details | |
| Raffles Hospital | RECRUITING | Singapore | 188770 | Singapore | Details | |
| Tang Tock Seng Hospital | RECRUITING | Singapore | 308433 | Singapore | Details | |
| Hospital Clinic de Barcelona | RECRUITING | Barcelona | 08036 | Spain | Details | |
| Hospital de la Santa Creu i de Sant Pau | RECRUITING | Barcelona | 08041 | Spain | Details | |
| Hospital Universitari Dexeus (USP Institut Universitari Dexeus/Hospital Universitari Quiron Dexeus) | RECRUITING | Barcelona | 8028 | Spain | Details | |
| Hospital Universitari Vall D'Hebron | RECRUITING | Barcelona | 8035 | Spain | Details | |
| Hospital Parc Tauli | RECRUITING | Barcelona | 8208 | Spain | Details | |
| Hospital Universitario Reina Sofia | RECRUITING | Cordoba | 14004 | Spain | Details | |
| Hospital Doctor Josep Trueta | RECRUITING | Girona | 17007 | Spain | Details | |
| Hospital Universitario de Jaen | RECRUITING | Jaen | 23007 | Spain | Details | |
| Hospital Universitario de Canarias | RECRUITING | Las Palmas de G.C. | 35016 | Spain | Details | |
| Hospital Universitario Fundacion Jimenez Diaz | RECRUITING | Madrid | 28020 | Spain | Details | |
| Clinica Universidad de Navarra | RECRUITING | Madrid | 28027 | Spain | Details | |
| Hospital Universitario La Paz | RECRUITING | Madrid | 28046 | Spain | Details | |
| Hospital Universitario Puerta de Hierro de Majadahonda | RECRUITING | Majadahonda | 28222 | Spain | Details | |
| Hospital Sant Joan de Reus | RECRUITING | Reus | 43204 | Spain | Details | |
| Hospital Regional Universitario de Malaga | RECRUITING | Rincon de la Victoria | 29011 | Spain | Details | |
| Hospital Universitario Virgen Macarena | RECRUITING | Sevilla | 41009 | Spain | Details | |
| Hospital Universitario Virgen del Rocio | RECRUITING | Seville | 41014 | Spain | Details | |
| Instituto Valenciano De Oncologia (IVO) | RECRUITING | Valencia | 46009 | Spain | Details | |
| Hospital Universitari i Politecnic La Fe | RECRUITING | Valencia | 46015 | Spain | Details | |
| Hospital Vithas Valencia 9 de Octubre | RECRUITING | Valencia | 46015 | Spain | Details | |
| Changhua Christian Hospital | RECRUITING | Changhua City | 500-06 | Taiwan | Details | |
| E-DA Hospital | RECRUITING | Kaohsiung City | 824 | Taiwan | Details | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital | RECRUITING | Kaohsiung | 807 | Taiwan | Details | |
| Chang Gung Memorial Hospital Kaohsiung | RECRUITING | Kaohsiung | 83301 | Taiwan | Details | |
| National Cheng Kung University Hospital | RECRUITING | Tainan | 70403 | Taiwan | Details | |
| Chi Mei Hospital, Liouying | RECRUITING | Tainan | Taiwan | Details | ||
| National Taiwan University Hospital | RECRUITING | Taipei City | 100 | Taiwan | Details | |
| Taipei Veterans General Hospital | RECRUITING | Taipei | 10002 | Taiwan | Details | |
| Chang Gung Memorial Hospital Linkou Branch of the Chang Gung Medical Foundation | RECRUITING | Taoyuan City | 33305 | Taiwan | Details | |
| Ankara Bilkent Sehir Hastanesi | RECRUITING | Ankara | 06550 | Turkey | Details | |
| Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi | RECRUITING | Ankara | 6200 | Turkey | Details | |
| Trakya University Faculty of Medicine | RECRUITING | Edirne | 22030 | Turkey | Details | |
| Istanbul University Cerrahpasa Medical Faculty Hospital | RECRUITING | Fatih | 34098 | Turkey | Details | |
| Goztepe Prof. Dr. Suleyman Yalcın Sehir Hastanesi | RECRUITING | Istanbul | 34093 | Turkey | Details | |
| Medipol Mega University Hospital | RECRUITING | Istanbul | Turkey | Details | ||
| Acibadem Mehmet Ali Aydinlar Universitesi Atakent Hastanesi | RECRUITING | Kaakaekmece | 34303 | Turkey | Details | |
| Turgut Ozal Medical Faculty | RECRUITING | Malatya | 44300 | Turkey | Details | |
| Colchester General Hospital | RECRUITING | Colchester | CO4 5JL | United Kingdom | Details | |
| St Bartholomew's Hospital, Barts Health NHS Trust | RECRUITING | London | EC1A 7BE | United Kingdom | Details | |
| University Hospital Southampton Nhs Foundation Trust | RECRUITING | Southampton | SO16 6YD | United Kingdom | Details |