Disease Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

ID DOID:3371
Name chondrosarcoma
Definition A bone sarcoma that has_material_basis_in cells derived from transformed cells that produce cartilage.
Source DiseaseOntology.org
Alt Ids DOID:3370
Path disease disease of cellular proliferation cancer organ system cancer musculoskeletal system cancer connective tissue cancer bone cancer bone sarcoma chondrosarcoma


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
IDH1 mutant Dasatinib chondrosarcoma resistant detail...
Unknown unknown Alisertib chondrosarcoma not applicable detail...
Unknown unknown Dasatinib chondrosarcoma not applicable detail...
Unknown unknown Pembrolizumab chondrosarcoma not applicable detail...
Unknown unknown Doxorubicin + Nilotinib chondrosarcoma not applicable detail...
IDH1 R132C Ivosidenib chondrosarcoma predicted - sensitive detail...
IDH1 R132G Ivosidenib chondrosarcoma predicted - sensitive detail...
IDH1 R132L Ivosidenib chondrosarcoma predicted - sensitive detail...
IDH1 R132S Ivosidenib chondrosarcoma predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT01446809 Phase I Doxorubicin + Ifosfamide Doxorubicin + Ifosfamide + Pazopanib Pazopanib Hydrochloride Followed By Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma Completed
NCT03190174 Phase Ib/II Nab-Rapamycin + Nivolumab Nivolumab (Opdivo) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma Recruiting
NCT03282344 Phase II Nivolumab + NKTR-214 A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma Active, not recruiting
NCT03684811 Phase Ib/II Cisplatin + Gemcitabine + Olutasidenib Azacitidine + Olutasidenib Olutasidenib Nivolumab + Olutasidenib A Study of FT 2102 in Participants With Advanced Solid Tumors and Gliomas With an IDH1 Mutation Active, not recruiting
NCT04040205 Phase II Abemaciclib Abemaciclib for Treatment of Advanced Bone and Soft Tissue Sarcoma Identified as Having CDK Pathway Alteration Recruiting
NCT04278781 Phase II Ivosidenib AG-120 in People With IDH1 Mutant Chondrosarcoma Recruiting