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ID DOID:3905
Name lung carcinoma
Definition A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer respiratory system cancer lung cancer lung carcinoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
BRAF V600E Dasatinib lung carcinoma resistant detail...
RB1 wild-type TP53 wild-type R547 lung carcinoma sensitive detail...
TP53 wild-type Ceralasertib + Radiotherapy lung carcinoma sensitive detail...
FGFR1 amp Lucitanib lung carcinoma sensitive detail...
NRAS Q61K LY3214996 lung carcinoma sensitive detail...
NRAS Q61K Abemaciclib + LY3214996 lung carcinoma sensitive detail...
PIK3CA K111R PIK3CA H1047R STX-478 lung carcinoma sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02834013 Phase 0 Ipilimumab + Nivolumab Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Active, not recruiting USA 1
NCT02960594 Phase I INO-1400 + INO-9012 INO-1400 hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse Completed USA 0
NCT05143970 Phase I IPH5301 IPH5301 + Paclitaxel + Trastuzumab A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors (CHANCES) Recruiting FRA 0