Disease Detail

ID DOID:3905
Name lung carcinoma
Definition A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer respiratory system cancer lung cancer lung carcinoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Unknown unknown Buparlisib + Everolimus lung carcinoma not applicable detail...
BRAF V600E Dasatinib lung carcinoma resistant detail...
MET T1010I Crizotinib lung carcinoma sensitive detail...
TP53 wild-type RB1 wild-type R547 lung carcinoma sensitive detail...
Unknown unknown YW3-56 lung carcinoma not applicable detail...
Unknown unknown NGR-TNF lung carcinoma not applicable detail...
Unknown unknown INCB001158 lung carcinoma predicted - sensitive detail...
Unknown unknown MGCD516 lung carcinoma not applicable detail...
TP53 wild-type AZD6738 + Radiotherapy lung carcinoma sensitive detail...
KRAS G12S AZD4785 lung carcinoma sensitive detail...
KRAS mutant AZD4785 lung carcinoma sensitive detail...
KRAS wild-type AZD4785 lung carcinoma decreased response detail...
FGFR1 amp Lucitanib lung carcinoma sensitive detail...
Unknown unknown MRx0518 lung carcinoma not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT02834013 Phase 0 Ipilimumab + Nivolumab Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting
NCT02960594 Phase I INO-1400 + INO-9012 INO-1400 hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse Completed