Disease Detail


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ID DOID:50619
Name paranasal sinus cancer
Definition A respiratory system cancer that is located_in the paranasal sinuses.
Source DiseaseOntology.org
Alt Ids DOID:2442 DOID:2767 DOID:4689 DOID:1354 DOID:2765
Path disease disease of cellular proliferation cancer organ system cancer respiratory system cancer paranasal sinus cancer


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01540682 Phase I Alisertib + Cetuximab MLN8237 in Head and Neck Cancer Completed USA 0
NCT02196168 Phase II Adavosertib Cisplatin Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Terminated CAN 0
NCT02538510 Phase Ib/II Pembrolizumab + Vorinostat Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer and Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery Active, not recruiting USA 0
NCT02567422 Phase I Berzosertib + Cisplatin VX-970, Cisplatin, and Radiation Therapy in Treating Patients With Locally Advanced HPV-Negative Head and Neck Squamous Cell Carcinoma Active, not recruiting USA 0
NCT02795156 Phase II Cabozantinib Afatinib Regorafenib Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations Completed USA 0
NCT02834013 Phase 0 Ipilimumab + Nivolumab Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Active, not recruiting USA 1
NCT02994069 Phase II Cisplatin Cisplatin + Radiation in SCCHN and Correlation With Oxidative Stress Markers Recruiting USA 0
NCT03238365 Phase I Nivolumab + Tadalafil Nivolumab Nivolumab With or Without Tadalafil in Treating Patients With Recurrent Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery Completed USA 0
NCT03370276 Phase Ib/II Cetuximab + Nivolumab Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma Active, not recruiting USA 0
NCT03381183 Phase Ib/II Cyclophosphamide + Durvalumab + Tremelimumab IRX-2 Regimen, Durvalumab, Tremelimumab for Incurable Head and Neck Squamous Cell Carcinoma Active, not recruiting USA 0
NCT03422536 Phase II Ficlatuzumab Cetuximab + Ficlatuzumab Ficlatuzumab With or Without Cetuximab in Treating Patients With Cetuximab-Resistant, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Completed USA 0
NCT03539198 Phase 0 Nivolumab Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer Terminated USA 0
NCT03719690 Phase II Tipifarnib Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy (AIM-HN/SEQ-HN) Active, not recruiting USA | ITA | ESP | DEU | BEL | AUT 10
NCT04290546 Phase I ALT-803 + CIML-NK cells + Ipilimumab ALT-803 + CIML-NK cells CIML NK Cell in Head & Neck Cancer Recruiting USA 0
NCT04722523 Phase I Cemiplimab + Cetuximab + Cisplatin + Docetaxel Carboplatin + Cemiplimab + Cetuximab + Docetaxel A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer Recruiting USA 0
NCT05027633 Phase II Cisplatin + Docetaxel + Pembrolizumab Carboplatin + Docetaxel + Pembrolizumab Immunotherapy With Chemotherapy and Chemoradiation for Advanced Squamous Cancer of Nasal Cavity / Paranasal Sinuses (I-NAPA) Recruiting USA 0
NCT05057247 Phase II Docetaxel + Duvelisib Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC Recruiting USA 0
NCT05172245 Phase I Cisplatin + Ipatasertib Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Stage III-IVB Head and Neck Cancer Recruiting USA | CAN 0