Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Icatolimab
Trade Name
Synonyms JS004|JS-004|JS 004|TAB004|TAB-004|TAB 004|Tifcemalimab
Drug Descriptions

Icatolimab (JS004) is a humanized monoclonal antibody that binds to B- and T-lymphocyte attenuator (BTLA) and activates T-cells, thereby potentially resulting in the activation of antitumor immune response (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2643).

CAS Registry Number NA
NCIT ID C168617


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Icatolimab Icatolimab 0 1
Icatolimab + Toripalimab-tpzi Icatolimab Toripalimab-tpzi 0 1

Additional content available in CKB BOOST