Drug Detail


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Drug Name TPST-1495
Trade Name
Synonyms TPST1495|TPST 1495
Drug Descriptions

TPST-1495 is a dual antagonist that selectively inhibits EP2 and EP4, and reverses Prostaglandin E2 mediated immune suppression, potentially resulting in enhanced antitumor immune response and tumor growth inhibition (Journal for ImmunoTherapy of Cancer 2019;7:282, Abs nr: P311).

CAS Registry Number NA
NCIT ID C174460


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + TPST-1495 Pembrolizumab TPST-1495 0 1
TPST-1495 TPST-1495 0 1
TPST-1495 + unspecified PD-1 antibody TPST-1495 unspecified PD-1 antibody 0 0

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