Drug Detail


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Drug Name ALLO-715
Trade Name
Synonyms ALLO715|ALLO 715
Drug Descriptions

ALLO-715 consists of a preparation of allogeneic T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets BCMA, with disruption of TCR alpha and CD52 to potentially reduce risk of GVHD and resistance to CD52 antibody therapy, which may enhance cytotoxicity against tumor cells expressing BCMA (Blood (2018) 132 (Supplement 1): 591).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
ALLO-647 + ALLO-715 ALLO-647 ALLO-715 0 1
ALLO-647 + ALLO-715 + Cyclophosphamide + Fludarabine ALLO-647 ALLO-715 Cyclophosphamide Fludarabine 0 1
ALLO-715 ALLO-715 0 0

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