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Drug Name ADC ST8176AA1
Trade Name
Synonyms Trastuzumab-HDACi ST8176AA1|ST8176AA1 ADC|ST8176AA1-ADC
Drug Descriptions

ADC ST8176AA1 is an antibody-drug conjugate (ADC) comprising Herceptin (trastuzumab), an ERBB2 (HER2) antibody, linked to ST7464AA1, which delivers the HDAC inhibitor to tumor cells expressing ERBB2 (HER2), potentially inhibiting Erbb2 signaling, and resulting in increased DNA damage and apoptosis, and reduced cell proliferation and tumor growth (PMID: 32039017).

DrugClasses HER2 (ERBB2) Antibody 72 HER2 (ERBB2) Antibody-Drug Conjugate 27
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ADC ST8176AA1 ADC ST8176AA1 0 0


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