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Drug Name | CD5 CAR T cells |
Trade Name | |
Synonyms | autologous CD5.CAR/28zeta CAR T cells|Anti-CD5 CAR T cells |
Drug Descriptions |
CD5 CAR T cells consist of autologous T-cells engineered to express a chimeric antigen receptor (CAR) targeting CD5 fused to the intracellular signaling domain of CD28 and the T-cell receptor (TCR) zeta chain, which potentially induces cytotoxicity against tumor cells expressing CD5, and reduces tumor progression (PMID: 26056165). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C148490 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CD5 CAR T cells | CD5 CAR T cells | 0 | 1 |