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Drug Name NC318
Trade Name
Synonyms NC-318|NC 318|Anti-S15 mAb NC318
Drug Descriptions

NC318 is a monoclonal antibody that binds to sialic acid binding Ig-like lectin 15 (Siglec-15) expressed on tumor-associated macrophages, which potentially disrupts T-cell response inhibition, and may interfere with angiogenesis and tumor cell metastasis (PMID: 31806628).

DrugClasses
CAS Registry Number NA
NCIT ID C157061

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Therapy Name Drugs Efficacy Evidence Clinical Trials
NC318 NC318 0 2
NC318 + Pembrolizumab NC318 Pembrolizumab 0 1


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