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|Synonyms||NC-318|NC 318|Anti-S15 mAb NC318|
NC318 is a monoclonal antibody that binds to sialic acid binding Ig-like lectin 15 (Siglec-15) expressed on tumor-associated macrophages, which potentially disrupts T-cell response inhibition, and may interfere with angiogenesis and tumor cell metastasis (PMID: 31806628).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|NC318 + Pembrolizumab||NC318 Pembrolizumab||0||1|