Drug Detail


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Drug Name Brequinar
Trade Name
Synonyms DUP 785|DUP785|DUP-785|NSC368390|NSC-368390|NSC 368390|Bipenquinate
Drug Descriptions

Brequinar (DUP 785) is a small molecule that selectively inhibits the activity of Dihydroorotate dehydrogenase (DHODH), potentially resulting in increased myeloid differentiation and decreased tumor burden (PMID: 27641501, PMID: 32525770).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
Brequinar Brequinar 1 1

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