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Drug Name GLYCAR T cells
Trade Name
Synonyms GPC3 CAR T cells|CAR-GPC3 T Cells|Glypican-3 CAR T Cells
Drug Descriptions

GLYCAR T cells consist of a preparation of autologous peripheral blood mononuclear cells engineered to express a chimeric antigen receptor (CAR) targeting GPC3 linked to CD8 alpha hinge domain, CD28 transmembrane domain, and CD3zeta signaling domain, which may lead to antitumor activity, including reduced tumor growth in GPC3-positive tumor cells (PMID: 32371538).

DrugClasses
CAS Registry Number NA
NCIT ID C121638

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Therapy Name Drugs Efficacy Evidence Clinical Trials
GLYCAR T cells GLYCAR T cells 0 1
GLYCAR T cells + Sorafenib GLYCAR T cells Sorafenib 0 0


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