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Drug Name GEN1046
Trade Name
Synonyms GEN-1046|GEN 1046|DuoBody-PD-L1x4-1BB|BNT 311
Drug Descriptions

GEN1046 is a bispecific antibody that binds to and simultaneously targets PD-L1 and TNFRSF9 (4-1BB), potentially resulting in the activation of T-lymphocytes, leading to increased anti-tumor immune response and decreased tumor growth (J. Immunotherapy Cancer, 6, 115 (2018), Abs nr: P647).

DrugClasses PD-L1/PD-1 antibody 69
CAS Registry Number NA
NCIT ID C172194


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Therapy Name Drugs Efficacy Evidence Clinical Trials
GEN1046 GEN1046 0 1

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