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|Synonyms||GEN-1046|GEN 1046|DuoBody-PD-L1x4-1BB|BNT 311|
GEN1046 is a bispecific antibody that binds to and simultaneously targets PD-L1 and TNFRSF9 (4-1BB), potentially resulting in the activation of T-lymphocytes, leading to increased anti-tumor immune response and decreased tumor growth (J. Immunotherapy Cancer, 6, 115 (2018), Abs nr: P647).
|DrugClasses||PD-L1/PD-1 antibody 69|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|