Drug Detail


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Drug Name Nidanilimab
Trade Name
Synonyms CAN04|CAN 04|CAN-04
Drug Descriptions

Nidanilimab is a humanized monoclonal antibody that targets l1rap, which inhibits downstream signaling and blocks activation of NFkappa-B, thereby potentially inducing antibody-dependent cellular cytotoxicity, leading to decreased proliferation and increased death of tumor cells expressing IL1RAP (NCI Drug Dictionary).

CAS Registry Number 2171061-85-9
NCIT ID C153375


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Gemcitabine + Nidanilimab Carboplatin Gemcitabine Nidanilimab 0 1
Cisplatin + Gemcitabine + Nidanilimab Cisplatin Gemcitabine Nidanilimab 0 2
Docetaxel + Nidanilimab Docetaxel Nidanilimab 0 1
Fluorouracil + Irinotecan + Leucovorin + Nidanilimab + Oxaliplatin Fluorouracil Irinotecan Leucovorin Nidanilimab Oxaliplatin 0 1
Fluorouracil + Leucovorin + Nidanilimab + Oxaliplatin Fluorouracil Leucovorin Nidanilimab Oxaliplatin 0 1
Gemcitabine + Nab-paclitaxel + Nidanilimab Gemcitabine Nab-paclitaxel Nidanilimab 0 1
Nidanilimab Nidanilimab 0 1
Nidanilimab + Pembrolizumab Nidanilimab Pembrolizumab 0 1

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