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Drug Name DPV-001
Trade Name
Synonyms DPV 001|DPV001
Drug Descriptions

DPV-001 is a cancer vaccine consisting of dendritic cell targeting microvesicles (DRibbles), which are autophagosomes derived from two non-small cell lung carcinoma cell lines (UbiLT3 and UbiLT6) that contain numerous tumor-associated antigens, including DAMPs, and delivers stable short-lived proteins (SLiPs) and defective ribosomal products (DRiPs), potential resulting in the induction of antitumor immune response (JITC 2015; 3(Suppl 2): P435; JITC 2013; 1(Suppl 1): P260).

DrugClasses
CAS Registry Number NA
NCIT ID C107681

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Therapy Name Drugs Efficacy Evidence Clinical Trials
DPV-001 DPV-001 0 0
DPV-001 + INCAGN01876 + Retifanlimab DPV-001 INCAGN01876 Retifanlimab 0 1
DPV-001 + Retifanlimab DPV-001 Retifanlimab 0 1


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