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Drug Name HMPL-306
Trade Name
Synonyms HMPL 306|HMPL306
Drug Descriptions

HMPL-306 specifically inhibits mutant IDH1/2, resulting in decreased conversion of alpha-ketoglutarate into 2-hydroxyglutarate, and potentially leading to inhibition of of IDH1/2 mutant tumor cell proliferation (NCI Drug Dictionary).

DrugClasses IDH Inhibitor (Pan) 3
CAS Registry Number NA
NCIT ID C175602

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Therapy Name Drugs Efficacy Evidence Clinical Trials
HMPL-306 HMPL-306 3 2


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