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| Drug Name | TSA/TAA-specific TCR engineered T cells |
| Trade Name | |
| Synonyms | TCR-transduced T cells|TSA-reactive TCR-engineered T cells |
| Drug Descriptions |
TSA/TAA-specific TCR engineered T cells consist of T-lymphocytes engineered to express a T-cell receptor (TCR) that targets tumor-specific antigens (TSA) or tumor-associated antigens (TAA), which potentially induces cytotoxic response against TSA or TAA-expressing tumor cells (PMID: 20454585). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CDX-1140 + Pembrolizumab + TSA/TAA-specific TCR engineered T cells | CDX-1140 Pembrolizumab TSA/TAA-specific TCR engineered T cells | 0 | 2 |
| TSA/TAA-specific TCR engineered T cells | TSA/TAA-specific TCR engineered T cells | 0 | 0 |
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