Drug Detail


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Drug Name BNT111
Trade Name
Synonyms BNT-111|BNT 111
Drug Descriptions

BNT111 is a liposomal RNA vaccine comprising mRNA transcripts that encode wild-type NY-ESO1, MAGE-A3, TYR (aa 1-477), and TPTE tumor specific antigens (TSAs), which is targeted to and expressed in dendritic cells, potentially inducing cytotoxic T-cell response against NY-ESO1, MAGE-A3, TYR, and TPTE expressing tumor cells (PMID: 32728218).

CAS Registry Number NA
NCIT ID C122396


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Therapy Name Drugs Efficacy Evidence Clinical Trials
BNT111 BNT111 0 1
BNT111 + Cemiplimab BNT111 Cemiplimab 0 1
BNT111 + Nivolumab BNT111 Nivolumab 0 0
BNT111 + Pembrolizumab BNT111 Pembrolizumab 0 0
BNT111 + unspecified PD-1 antibody BNT111 unspecified PD-1 antibody 0 0

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