Drug Detail


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Drug Name BLU-945
Trade Name
Synonyms BLU 945|BLU945
Drug Descriptions

BLU-945 is a wild-type-sparing 4th generation EGFR inhibitor with activity against EGFR T790M and EGFR C797S, which may block EGFR signaling and lead to tumor growth inhibition (PMID: 35838760).

DrugClasses EGFR Inhibitor 4th gen 14
CAS Registry Number 2660250-10-0
NCIT ID C180668


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Therapy Name Drugs Efficacy Evidence Clinical Trials
BLU-945 BLU-945 0 1
BLU-945 + Osimertinib BLU-945 Osimertinib 0 1
BLU-945 + Panitumumab BLU-945 Panitumumab 0 0

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