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BLU-945 is a wild-type-sparing 4th generation EGFR inhibitor with activity against EGFR T790M and EGFR C797S, which may block EGFR signaling and lead to tumor growth inhibition (PMID: 35838760).
|DrugClasses||EGFR Inhibitor 4th gen 12|
|CAS Registry Number||2660250-10-0|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|BLU-945 + Osimertinib||BLU-945 Osimertinib||0||1|