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EMB-02 is a bispecific antibody that targets both PD-1 (CD279) and lymphocyte activation gene 3 protein (LAG-3), and prevents the PD-1- and LAG-3-dependent decrease in T-cell activation and proliferation, which may potentially lead to a cytotoxic T lymphocyte response against tumor cells (NCI Drug Dictionary).
|DrugClasses||Immune Checkpoint Inhibitor 135 LAG3 Antibody 15 PD-L1/PD-1 antibody 80|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|