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Drug Name | BAY-293 |
Trade Name | |
Synonyms | BAY293|BAY 293 |
Drug Descriptions |
BAY-293 inhibits the interaction between Sos1 and Kras, leading to reduced Ras activation and downstream Erk phosphorylation, and potentially leading to decreased tumor cell proliferation (PMID: 30683722). |
DrugClasses | SOS1 Inhibitor 6 |
CAS Registry Number | 2244904-70-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ARS-853 + BAY-293 | ARS-853 BAY-293 | 0 | 0 |
BAY-293 | BAY-293 | 0 | 0 |
BAY-293 + Gefitinib | BAY-293 Gefitinib | 0 | 0 |
BAY-293 + Osimertinib | BAY-293 Osimertinib | 0 | 0 |
BAY-293 + Osimertinib + RMC-4550 | BAY-293 Osimertinib RMC-4550 | 0 | 0 |
BAY-293 + RMC-4550 | BAY-293 RMC-4550 | 0 | 0 |