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Drug Name BAY-293
Trade Name
Synonyms BAY293|BAY 293
Drug Descriptions

BAY-293 inhibits the interaction between Sos1 and Kras, leading to reduced Ras activation and downstream Erk phosphorylation, and potentially leading to decreased tumor cell proliferation (PMID: 30683722).

DrugClasses SOS1 Inhibitor 13
CAS Registry Number 2244904-70-7


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alvocidib + BAY-293 Alvocidib BAY-293 0 0
ARS-853 + BAY-293 ARS-853 BAY-293 0 0
BAY-293 BAY-293 0 0
BAY-293 + Cisplatin BAY-293 Cisplatin 0 0
BAY-293 + Gefitinib BAY-293 Gefitinib 0 0
BAY-293 + Osimertinib BAY-293 Osimertinib 0 0
BAY-293 + Osimertinib + RMC-4550 BAY-293 Osimertinib RMC-4550 0 0
BAY-293 + Palbociclib BAY-293 Palbociclib 0 0
BAY-293 + PD98059 BAY-293 PD98059 0 0
BAY-293 + Pemetrexed Disodium BAY-293 Pemetrexed Disodium 0 0
BAY-293 + RMC-4550 BAY-293 RMC-4550 0 0
BAY-293 + Sirolimus BAY-293 Sirolimus 0 0
BAY-293 + SN-38 BAY-293 SN-38 0 0
BAY-293 + Trametinib BAY-293 Trametinib 0 0

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