Drug Detail


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Drug Name GDC-6036
Trade Name
Synonyms GDC6036|GDC 6036
Drug Descriptions

GDC-6036 is a selective inhibitor of KRAS G12C that blocks downstream signaling, and may lead to anti-tumor activity (Annals of Oncology (2022) 33 (suppl_7): S197-S224).

DrugClasses KRAS G12C inhibitor 28
CAS Registry Number NA
NCIT ID C173995


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + GDC-6036 Atezolizumab GDC-6036 0 1
Bevacizumab + GDC-6036 Bevacizumab GDC-6036 0 1
Cetuximab + GDC-6036 Cetuximab GDC-6036 0 1
Erlotinib + GDC-6036 Erlotinib GDC-6036 0 1
GDC-6036 GDC-6036 0 1
GDC-6036 + RLY-1971 GDC-6036 RLY-1971 0 0

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