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Drug Name | PC14586 |
Trade Name | |
Synonyms | PC 14586|PC-14586 |
Drug Descriptions |
PC14586 is a small molecule that stabilizes TP53 Y220C and reactivates TP53 function, which may lead to cell cycle arrest and growth inhibition (AACR Annual Meeting Apr 2021, Session MS.LBA01, Abstract # LB006). |
DrugClasses | p53 Activator 11 |
CAS Registry Number | NA |
NCIT ID | C175961 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
PC14586 | PC14586 | 7 | 1 |
PC14586 + Pembrolizumab | PC14586 Pembrolizumab | 0 | 1 |