Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name RPTR-147
Trade Name
Synonyms RPTR147|RPTR 147|PRIME IL-15
Drug Descriptions

RPTR-147 is a cell therapy that consists of autologous T-lymphocytes primed with PRAME, NYESO-1, SSX2, Survivin, and WT1 tumor associated antigens (TAAs), followed by IL15-Fc nanogel loading, which potentially induces immune response against tumor cells expressing TAAs (Journal for ImmunoTherapy of Cancer 2020;8; Abs nr: 801).

DrugClasses
CAS Registry Number NA
NCIT ID NA

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + RPTR-147 Pembrolizumab RPTR-147 0 1
RPTR-147 RPTR-147 0 1


Additional content available in CKB BOOST