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Drug Name MK-4280A
Trade Name
Synonyms MK4280A|MK 4280A
Drug Descriptions

MK-4280A is a coformulation of MK-4280 and Pembrolizumab, which potentially induces antitumor activity (J Clin Oncol 39, no. 15_suppl (May 20, 2021) 3584).

DrugClasses Immune Checkpoint Inhibitor 148 LAG3 Antibody 18 PD-L1/PD-1 antibody 117
CAS Registry Number NA
NCIT ID C190780

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Enfortumab vedotin-ejfv + MK-4280A Enfortumab vedotin-ejfv MK-4280A 0 1
Irinotecan + MK-4280A Irinotecan MK-4280A 0 1
Lenvatinib + MK-4280A Lenvatinib MK-4280A 0 2
MK-4280A MK-4280A 0 6
MK-4280A + Paclitaxel MK-4280A Paclitaxel 0 1


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