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Drug Name ENB003
Trade Name
Synonyms ENB-003|ENB 003|Vodudeutentan Sodium
Drug Descriptions

ENB003 is an an antagonist that selectively binds to endothelin B receptor (ETBR) and inhibits downstream signaling, which potentially relieves tumor immunosuppression and inhibits proliferation of tumor cells expressing ETBR (Clin Cancer Res 2009;15(14):4521-4528; NCI Drug Dictionary).

DrugClasses
CAS Registry Number 2364572-10-9
NCIT ID C175447

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ENB003 ENB003 0 0
ENB003 + Pembrolizumab ENB003 Pembrolizumab 0 1


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