Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name ART0380
Trade Name
Synonyms ART-0380|ART 0380
Drug Descriptions

ART0380 inhibits ATR activity leading to decreased phopshorylation of Chk1, which may result in impaired DNA damage repair and induction of apoptosis in tumor cells (NCI Drug Dictionary).

DrugClasses ATR Inhibitor 13
CAS Registry Number NA
NCIT ID C179292

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ART0380 ART0380 0 1
ART0380 + Gemcitabine ART0380 Gemcitabine 0 1


Additional content available in CKB BOOST