Drug Detail


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Drug Name D-1553
Trade Name
Synonyms D1553|D 1553|garsorasib
Drug Descriptions

D-1553 (garsorasib) inhibits KRAS G12C, which potentially results in decreased tumor growth (Cancer Res 2021;81(13_Suppl):Abstract nr 932, PMID: 36948246).

DrugClasses KRAS G12C inhibitor 32
CAS Registry Number 2559761-14-5
NCIT ID C178562


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + D-1553 Carboplatin D-1553 0 0
Cetuximab + D-1553 Cetuximab D-1553 0 0
Cisplatin + D-1553 Cisplatin D-1553 0 0
D-1553 D-1553 0 1
D-1553 + Oxaliplatin D-1553 Oxaliplatin 0 0
D-1553 + RMC-4550 D-1553 RMC-4550 0 0
D-1553 + Trametinib D-1553 Trametinib 0 0

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