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Drug Name Epcoritamab
Trade Name
Synonyms DuoBody-CD3xCD20|GEN 3013|GEN-3013|GEN3013
Drug Descriptions

Epcoritamab (GEN3013) is a bispecific antibody that targets CD3 and CD20, resulting in T-cell activation and redirection of T-cells to CD20-expressing tumor cells, which may lead to tumor cell cytotoxicity and inhibition of tumor growth (PMID: 31981978, PMID: 33602901).

DrugClasses CD20 Antibody 12 CD3 Antibody 33
CAS Registry Number NA
NCIT ID C163022

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bendamustine + Epcoritamab + Rituximab Bendamustine Epcoritamab Rituximab 0 1
Cisplatin + Cytarabine + Dexamethasone + Epcoritamab + Rituximab Cisplatin Cytarabine Dexamethasone Epcoritamab Rituximab 0 1
Cyclophosphamide + Doxorubicin + Epcoritamab + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Epcoritamab Prednisone Rituximab Vincristine Sulfate 0 1
Epcoritamab Epcoritamab 0 3
Epcoritamab + Gemcitabine + Oxaliplatin Epcoritamab Gemcitabine Oxaliplatin 0 1
Epcoritamab + Lenalidomide + Rituximab Epcoritamab Lenalidomide Rituximab 0 1


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