Drug Detail


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Drug Name JDQ443
Trade Name
Synonyms JDQ 443|JDQ-443
Drug Descriptions

JDQ443 inhibits KRAS G12C, which may lead to inhibition of downstream signaling and tumor progression (PMID: 35404998).

DrugClasses KRAS G12C inhibitor 33
CAS Registry Number NA
NCIT ID C177916


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cetuximab + JDQ443 Cetuximab JDQ443 0 1
IAG933 + JDQ443 IAG933 JDQ443 0 0
JDQ443 JDQ443 2 4
JDQ443 + Ribociclib JDQ443 Ribociclib 0 1
JDQ443 + Spartalizumab JDQ443 Spartalizumab 0 0
JDQ443 + Spartalizumab + TNO155 JDQ443 Spartalizumab TNO155 0 0
JDQ443 + Tislelizumab JDQ443 Tislelizumab 0 1
JDQ443 + Tislelizumab + TNO155 JDQ443 TNO155 Tislelizumab 0 1
JDQ443 + TNO155 JDQ443 TNO155 0 1
JDQ443 + Trametinib JDQ443 Trametinib 0 1

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