Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||TriTAC HPN328|HPN-328|DLL3/CD3e TriTAC HPN328|Anti-DLL3 T-cell Engager HPN328|
HPN328 is a tri-specific molecule that simultaneously binds to DLL3 on tumor cells and CD3 on T cells, potentially resulting in an upregulation and activation of T cells and subsequent increased death of DLL3-expressing tumor cells (Mol Cancer Ther 2019;18(12 Suppl):Abstract nr C033).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|