Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name TAS1440
Trade Name
Synonyms TAS 1440|TAS-1440
Drug Descriptions

TAS1440 binds to and inhibits the lysine-specific demethylase LSD1, which may lead to inhibition of cell growth in tumor cells with LSD1 overexpression (NCI Thesaurus).

DrugClasses KDM1A Inhibitor 15
CAS Registry Number NA
NCIT ID C175973

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
TAS1440 TAS1440 0 1
TAS1440 + Tretinoin TAS1440 Tretinoin 0 1


Additional content available in CKB BOOST