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Drug Name CD19-CAR(Mem) T-cells
Trade Name
Synonyms CD19-CAR.CD45RA-negative T-cells
Drug Descriptions

CD19-CAR(Mem) T-cells are a preparation of CD45RA-negative T cells engineered to express a chimeric antigen receptor (CAR) targeting CD19, containing 4-1BB and CD3-zeta signaling domains and a variable fragment of a CD19 antibody, which may potentially lead to tumor cell lysis (PMID: 24888271).

DrugClasses
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CD19-CAR(Mem) T-cells CD19-CAR(Mem) T-cells 0 0
CD19-CAR(Mem) T-cells + Cyclophosphamide + Fludarabine + Mesna CD19-CAR(Mem) T-cells Cyclophosphamide Fludarabine Mesna 0 1


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