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|Drug Name||CD19-CAR(Mem) T-cells|
CD19-CAR(Mem) T-cells are a preparation of CD45RA-negative T cells engineered to express a chimeric antigen receptor (CAR) targeting CD19, containing 4-1BB and CD3-zeta signaling domains and a variable fragment of a CD19 antibody, which may potentially lead to tumor cell lysis (PMID: 24888271).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|CD19-CAR(Mem) T-cells||CD19-CAR(Mem) T-cells||0||0|
|CD19-CAR(Mem) T-cells + Cyclophosphamide + Fludarabine + Mesna||CD19-CAR(Mem) T-cells Cyclophosphamide Fludarabine Mesna||0||1|