Drug Detail


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Drug Name HX008
Trade Name
Synonyms HX-008|HX 008|Pucotenlimab
Drug Descriptions

HX008 is a monoclonal antibody that binds to PD-1 (PDCD1) andblocks its interaction with PD-L1 (CD274) and PD-L2 (PDCD1LG2), blocking downstream signaling and potentially leading to activation of T-cell-mediated immune response against tumor cells and inhibition of tumor growth (PMID: 32106752).

DrugClasses Immune Checkpoint Inhibitor 151 PD-L1/PD-1 antibody 98
CAS Registry Number NA
NCIT ID C160717


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capecitabine + HX008 + Oxaliplatin Capecitabine HX008 Oxaliplatin 2 0
Cisplatin + Gemcitabine + HX008 Cisplatin Gemcitabine HX008 0 0
HX008 HX008 0 0
HX008 + Irinotecan HX008 Irinotecan 2 0
HX008 + OH2 HX008 OH2 0 0

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