Drug Detail


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Drug Name PY314
Trade Name
Synonyms PY-314|PY 314
Drug Descriptions

PY314 is a monoclonal antibody that targets TREM2 expressed on tumor-associated macrophages (TAMs), potentially resulting in depletion of M2-like TAMs, activation of the immune response, and anti-tumor activity (Mol Cancer Ther 2019;18(12 Suppl):Abstract nr C104).

CAS Registry Number NA
NCIT ID C179597


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + PY314 PY314 Pembrolizumab 0 1
PY314 PY314 0 1

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